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Introduction
Dextrocardia with situs inversus is a rare congenital condition with a prevalence of 1:10,000. There are few studies in the literature that have described myocardial perfusion imaging (MPI) in this patient population and the publications are mainly case reports.1
The current case is presented in order to show that cadmium-zinc-telluride (CZT) camera especially dedicated for the heart can be used to perform MPI in patients with dextrocardia.
Case Report
A 77-year old male with known dextrocardia in situs in versus and hypertension was referred to our clinic to investigate whether his experienced symptoms were related to myocardial ischemia (Figure 1). The patient was examined according to a two-day stress-rest protocol with regadenoson in combination with bicycle ergometry. Technetium (99mTc) tetrofosmin 99mTc tetrofosmin (639 MBq) was injected 30 seconds after regadenoson was administrated.2
MPI were first acquired by a single photon emission tomography/ computed tomography (SPECT/CT; Symbia T16, Siemens Healthineeers, Erlangen, Germany) equipped with low energy high resolution collimator and MPI were reconstructed by a specific software for dextrocardia (HERMES Medical Solutions, Stockholm, Sweden) (Figure 2). Another scan was consecutively performed within one hour with a cadmium-zinc-telluride SPECT with cardiac dedicated detector (D-SPECT, Spectrum Dynamics). In the cardiac dedicated camera, the patient was positioned in atypical position to have the heart in focus of the nine detector columns (Figures 3, 4) Rest images were obtained a few days later with the same acquisition protocol. MPI at stress and rest of both cameras presented a high quality of acquisition. Both scanners presented comparable and typical myocardial perfusion pattern without any signs of decreased uptake (Figure 5).
Conclusion
Hereby, we demonstrated that D-SPECT can reliable perform MPI in dextrocardia with situs inversus by a specific positioning of the body in the gantry.
References
Qutbi M. SPECT myocardial perfusion imaging in patients with Dextrocardia. J Nucl Cardiol 2019; 26:1197-04
Hyafil F, Gimelli A, Slart RHJA et al (2019) EANM procedural guidelines for myocardial perfusion scintigraphy using cardiac-centered gamma cameras. Eur J Hybrid Imaging 3:11. https://doi.org/10.1186/s41824-019-0058-2
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Forsberg, L., Soares, M. & Gonon, A. Myocardial perfusion imaging performed by dedicated cardiac cadmium-zinc-telluride camera in dextrocardia with situs inversus: A case report. J. Nucl. Cardiol. 29, 3599–3603 (2022). https://doi.org/10.1007/s12350-021-02696-6
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DOI: https://doi.org/10.1007/s12350-021-02696-6