Funding
Sponsorship for this study, article processing charges, and the open access fee were funded by AbbVie (North Chicago, IL, USA). AbbVie reviewed and approved the manuscript for submission.
Medical Writing and Editorial Assistance
Medical writing support was provided by Maria Hovenden, PhD, at Complete Publication Solutions, LLC (North Wales, PA, USA), a CHC Group company, and was funded by AbbVie.
Authorship
All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship for this manuscript, take responsibility for the integrity of the work as a whole, and have given final approval for the version to be published. All authors had full access to all of the data in this study and take complete responsibility for the integrity of the data and accuracy of the data analysis.
Disclosures
Edouard J. Louis has received fees for educational Grants from MSD, AbbVie, and Takeda; speakers fees from AbbVie, Ferring, MSD, Chiesi, Mitsubishi Pharma, Hospira, Janssen, and Takeda; and advisory board fees from AbbVie, Ferring, MSD, Takeda, Hospira, Mitsubishi Pharma, Celltrion, and Prometheus. Walter Reinisch has served as a speaker for Abbott Laboratories, AbbVie, Aesca, Aptalis, Astellas, Centocor, Celltrion, Danone Austria, Elan, Falk Pharma GmbH, Ferring, Immundiagnostik, Mitsubishi Tanabe Pharma Corporation, MSD, Otsuka, PDL, Pharmacosmos, PLS Education, Schering-Plough, Shire, Takeda, Therakos, Vifor, and Yakult; as a consultant for Abbott Laboratories, AbbVie, Aesca, Amgen, AM Pharma, Astellas, AstraZeneca, Avaxia, Roland Berger GmBH, Bioclinica, Biogen IDEC, Boehringer-Ingelheim, Bristol-Myers Squibb, Cellerix, Chemocentryx, Celgene, Centocor, Celltrion, Covance, Danone Austria, Elan, Ernst & Young, Falk Pharma GmbH, Ferring, Galapagos, Genentech, Gilead, Grünenthal, ICON, Index Pharma, Inova, Janssen, Johnson & Johnson, Kyowa Hakko Kirin Pharma, Lipid Therapeutics, Mallinckrodt, MedImmune, Millenium, Mitsubishi Tanabe Pharma Corporation, MSD, Nestle, Novartis, Ocera, Otsuka, Parexel, PDL, Pharmacosmos, Pfizer, Procter & Gamble, Prometheus, Robarts Clinical Trial, Schering-Plough, Second Genome, Setpointmedical, Sigmoid, Takeda, Therakos, Tigenix, UCB, Vifor, Zealand, Zyngenia, and 4SC; as an advisory board member for Abbott Laboratories, AbbVie, Aesca, Amgen, AM Pharma, Astellas, AstraZeneca, Avaxia, Biogen IDEC, Boehringer-Ingelheim, Bristol-Myers Squibb, Cellerix, Chemocentryx, Celgene, Centocor, Celltrion, Danone Austria, Elan, Ferring, Galapagos, Genentech, Grünenthal, Inova, Janssen, Johnson & Johnson, Kyowa Hakko Kirin Pharma, Lipid Therapeutics, MedImmune, Millenium, Mitsubishi Tanabe Pharma Corporation, MSD, Nestle, Novartis, Ocera, Otsuka, PDL, Pharmacosmos, Pfizer, Procter & Gamble, Prometheus, Schering-Plough, Second Genome, Setpointmedical, Takeda, Therakos, Tigenix, UCB, Zealand, Zyngenia, and 4SC; and has received research funding from Abbott Laboratories, AbbVie, Aesca, Centocor, Falk Pharma GmbH, Immundiagnostik, and MSD. David A. Schwartz has received Grant support from AbbVie and UCB and consultancy fees from AbbVie, UCB, Janssen, Takeda, and Tigenix. Robert Löfberg has received research Grants from Sophiahemmet and the Stichting af Jochnick Foundation; lecture fees from Abbott, Asahi-Kasei, AstraZeneca, Celltech, Centocor, Connexion, Cosmo, Elan, InDex Pharmaceuticals, Meda, Otsuka, Pharmacia-Pfizer, Schering-Plough, Schering AG, Serono, and UCB; and consultancy fees from Abbott, Asahi-Kasei, AstraZeneca, Celltech, Centocor, Connexion, Cosmo, Elan, InDex Pharmaceuticals, Meda, Otsuka, Pharmacia-Pfizer, Schering-Plough, Schering AG, Serono, and UCB. Anne M. Robinson is an AbbVie employee and may own AbbVie stock and/or options. Sofie Berg is an AbbVie employee and may own AbbVie stock and/or options. Anthony W. Wang is an AbbVie employee and may own AbbVie stock and/or options. Jen-fue Maa is an AbbVie employee and may own AbbVie stock and/or options. Bidan Huang is an AbbVie employee and may own AbbVie stock and/or options. Brandee Pappalardo is an AbbVie employee and may own AbbVie stock and/or options.
Compliance with Ethics Guidelines
This article does not contain any new studies with human or animal subjects performed by any of the authors.
Data Availability
The datasets generated during and/or analyzed during the current study are available on request through the “Clinical Trials Data & Information Sharing” portal (https://www.abbvie.com/our-science/clinical-trials/clinical-trials-data-and-information-sharing.html).
Open Access
This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.