This study was funded by GSK (GSK analysis: 202066) using data from three clinical trials that were also funded by GSK: NCT01316900/DB2113360, NCT01316913/DB2113374, and NCT01777334/ZEP117115. Article processing charges and the open access fee for this article were funded by GSK.
Editorial assistance in the preparation of the manuscript (in the form of writing assistance, assembling tables and figures, collating author comments, grammatical editing, and referencing) was provided by Natasha Thomas and Joanne Ashworth of Fishawack Indicia, Ltd., and was funded by GSK.
I. Naya is the guarantor of the paper, taking responsibility for the integrity of the work as a whole, from inception to published article.
I. Naya and L. Tombs were involved in the conception and design of the study. AA and MRMY were involved in the acquisition of data. All authors contributed to the data analysis and interpretation. All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship for this manuscript, contributed to the writing and reviewing of the manuscript, take responsibility for the integrity of the work as a whole, and have given final approval to the version to be published.
M. R. Maleki-Yazdi has acted as a consultant for Almirall, AstraZeneca, Boehringer Ingelheim, Forest Laboratories, GlaxoSmithKline (GSK), Novartis, Merck, Ono Pharmaceuticals, and Pfizer.
D. Singh has received sponsorship to attend international meetings, honoraria for lecturing or attending advisory boards and research grants from various pharmaceutical companies including Almirall, AstraZeneca, Boehringer Ingelheim, Chiesi, Genentech, GSK, Glenmark, Johnson & Johnson, Merck, NAPP, Novartis, Pfizer, Skyepharma, Takeda, Teva, Theravance, and Verona.
A. Anzueto acted as a consultant for AstraZeneca, Boehringer Ingelheim, Forest Laboratories, GSK, Novartis, and Pfizer.
I. Naya is an employee of GSK and holds stocks/shares in GSK.
W. A. Fahy is an employee of GSK and holds stocks/shares in GSK.
L. Tombs is a Contingent worker at GSK.
Compliance With Ethics Guidelines
All procedures followed in the studies were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1964, as revised in 2013. Informed consent was obtained from all patients for being included in the studies.
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