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Classics to Contemporary of Saccadic Dysmetria and Oscillations

  • Cerebellar Classic
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A CEREBELLAR CLASSIC to this article was published on 26 July 2022

Abstract

Clear vision requires accurate gaze shift from one object to the other and steadily maintaining it when eyes are at the target. The rapid gaze shifts are assured by the high-frequency burst in the brainstem neuronal firing, the mechanism relying on the tight cerebellar supervision. The cerebellar oversight is equally essential for maintaining gaze on the object of interest. The cerebellar significance on the motor control of gaze and the consequences of cerebellar illness are known for almost three quarters of the century – since David Cogan published the classic paper titled “Ocular Dysmetria, Flutter Like Oscillations of the Eyes, and Opsoclonus.” In this classic series of cases, three disorders of gaze shifting and gaze holding were described in a number of etiologies, ultimately manifesting in a final common pathway involving the cerebellum. Since the 1950s, there had been substantial progress in contemporary neurology, experimental neuroscience literature has expanded, and computational models of ocular motor control have flourished in the field. In this short commentary, I will highlight Cogan’s cerebellar classic in the context of contemporary research on motor control of saccades.

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Authors and Affiliations

  1. Department of Neurology, University Hospitals, 11100 Euclid Avenue, Cleveland, OH, 44110, USA

    Aasef G. Shaikh

  2. Neurology Service and Daroff-Dell’Osso Ocular Motility Laboratory, Louis Stokes Cleveland VA Medical Center, Cleveland, OH, USA

    Aasef G. Shaikh

  3. Departments of Neurology and Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA

    Aasef G. Shaikh

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Correspondence to Aasef G. Shaikh.

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Shaikh, A.G. Classics to Contemporary of Saccadic Dysmetria and Oscillations. Cerebellum 22, 527–530 (2023). https://doi.org/10.1007/s12311-022-01443-y

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  • DOI: https://doi.org/10.1007/s12311-022-01443-y

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