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High-intensity focused ultrasound—a needleless management for osteoid osteoma: a systematic review

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Abstract

Osteoid osteoma is one of the most frequent benign musculoskeletal neoplasm. Radiofrequency ablation is the method of choice for non-conservative treatment of osteoid osteoma. Recently, high-intensity focused ultrasound (HIFU) has been proposed as a safer option. The objective of this study is to review the efficacy and side effects of HIFU in the management of osteoid osteoma. A comprehensive search was conducted in PubMed, Science Direct, and Clinical Key until June 30, 2022. Demographic data, baseline characteristics, success rates, pre- and post-procedure pain scores, recurrences, and complications were recorded. Eleven studies were included in this systematic review. Pooled analysis that involved 186 subjects resulted in an overall success rate of 91.94%. Recurrence was reported in two studies, in which it occurred in 4/177 (2.26%) subjects. Skin burn was found in 1 (0.54%) patients. No major or other complications were reported. Three studies compared the success rate of HIFU and RFA. Success rate was slightly higher in the RFA group with insignificant difference (p = 0.15). High-intensity focused ultrasound showed promising results. It offers a safer treatment approach for osteoid osteoma, especially in children, and can be considered for recalcitrant cases after RFA. Nonetheless, more studies are expected in the future.

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Authors and Affiliations

  1. Faculty of Medicine, University of North Sumatera, Medan, Indonesia

    K. Ciatawi

  2. Department of Orthopaedic and Traumatology, Faculty of Medicine, Udayana University, Denpasar, Indonesia

    I. W. S. Dusak & I. G. E. Wiratnaya

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Ciatawi, K., Dusak, I.W.S. & Wiratnaya, I.G.E. High-intensity focused ultrasound—a needleless management for osteoid osteoma: a systematic review. Musculoskelet Surg 108, 21–30 (2024). https://doi.org/10.1007/s12306-023-00801-1

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