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Growth Factor Variation in Two Types of Autologous Platelet Biomaterials: PRP Versus PRF

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Indian Journal of Hematology and Blood Transfusion Aims and scope Submit manuscript

Abstract

Autologous platelet biomaterials represent a key source of cytokines and growth factors extensively used for clinical and surgical applications involving tissue regeneration; wound healing and tissue repair. In this communication we discuss the growth factors released by activated platelet rich plasma (PRP) and platelet rich fibrin (PRF) releasate. Our study highlights that significantly higher growth factors (TGF-ß1) are released by activated PRP as compared to releasate of PRF. The various growth factors released by both platelet products are significantly higher than the baseline concentration in the whole blood and have different bio-mechanism hence should be individualized as per the clinical indication.

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Acknowledgments

The authors were supported by Dr Ram Manohar Lohia Hospital, New Delhi.

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Authors and Affiliations

  1. Department of Transfusion Medicine, Dr Ram Manohar Lohia Hospital, New Delhi, India

    Satyam Arora, Urvershi Kotwal, Mitu Dogra & Veena Doda

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  1. Satyam Arora
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  2. Urvershi Kotwal
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  3. Mitu Dogra
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  4. Veena Doda
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Correspondence to Satyam Arora.

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Arora, S., Kotwal, U., Dogra, M. et al. Growth Factor Variation in Two Types of Autologous Platelet Biomaterials: PRP Versus PRF. Indian J Hematol Blood Transfus 33, 288–292 (2017). https://doi.org/10.1007/s12288-016-0721-8

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  • DOI: https://doi.org/10.1007/s12288-016-0721-8

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