Correction to: 3, 3′-Diindolylmethane-encapsulated chitosan nanoparticles accelerate molecular events during chemical carcinogen-induced mammary cancer in Sprague Dawley rats

Correction to: Breast Cancer (2019) 26:499–509 https://doi.org/10.1007/s12282-019-00950-x

In the original publication of the article, the Fig. 3 was published with errors. The correct Fig. 3 is given in this correction.

Fig. 3

Effect of DIM and DIM@CS-NP on the immunohistochemical analysis of Cyclin D1 (a–f) and PCNA (g–l), respectively, in mammary tissue of control and experimental rats. The control (a, g), DIM (e, k), and DIM@CS-NP (f, l) showed normal mammary tissue staining, the DMBA-induced rats (b, h) showed increased expression of Cyclin D1 and PCNA when compared with control rats. However, oral administration of DIM@CS-NP (d, j)-treated rats showed diminished expression levels as compared to DIM (c, i) administration

In addition, the first paragraph under the section heading “Immunohistochemical (IHC) expression of Cyclin D1 and PCNA in mammary tissues of control and experimental rats” should read as below:

The IHC expression of Cyclin D1 (A–F) and PCNA (G–L) in mammary tissues of control and experimental rats are represented in Fig. 3. The expression of Cyclin D1 and PCNA were found to be significantly increased in DMBA-induced tumor-bearing rats (B, H) when compared to control (A) rats. Whereas, the levels of Cyclin D1 and PCNA were found to be decreased during treatment with DIM@CS-NP 0.5 mg/kg b.wt (D and J) compared to DIM 10 mg/kg b.wt (C, I) significantly. However, the administration of DIM (E, K) and DIM@CS-NP (F, L) did not show any significant (p < 0.05) changes in the expression of Cyclin D1 and PCNA.