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Antimikrobielle Peptide – Inspiration aus der Natur
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  • Wissenschaft
  • Open Access
  • Published: 28 March 2022

Antimikrobielle Peptide – Inspiration aus der Natur

  • Alexandro Rodríguez-Rojas1 &
  • Jens Rolff1 

BIOspektrum volume 28, pages 135–137 (2022)Cite this article

  • 162 Accesses

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Abstract

Antimicrobial peptides (AMPs) are ancient immune effectors and are considered as new anti-infective drugs. AMPs differ from conventional antibiotics in their pharmacodynamics, speed of killing and they do not increase mutagenesis. This results in a much lower probability of bacterial resistance evolution against AMPs. AMPs are usually expressed as synergistic cocktails. If AMPs are to be used in the clinic to tackle the antibiotic crisis, understanding their natural biology will be pivotal to prevent resistance.

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Funding

Funding note: Open Access funding enabled and organized by Projekt DEAL.

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Authors and Affiliations

  1. Evolutionsbiologie Institut für Biologie, Freie Universität Berlin, Königin-Luise-Straße 1-3, D-14195, Berlin, Deutschland

    Alexandro Rodríguez-Rojas &  Jens Rolff

Authors
  1. Alexandro Rodríguez-Rojas
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  2. Jens Rolff
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Corresponding author

Correspondence to Jens Rolff.

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Danksagung

Wir danken allen Mitgliedern der AG Evolutionsbiologie und unseren Ko-Autoren und Ko-Autorinnen, die an den vorgestellten Arbeiten beteiligt waren, sowie Klaus Reinhardt für Feedback. Wir danken der DFG für die Förderung (SFB 973, FOR 5026).

Alexandro Rodríguez-Rojas Biologiestudium. 2001–2003 Forscher in F&E am Carlos J. Finnlay Impfstoffinstitut, Havanna, Kuba. 2004–2005 Forschungspraktikum, Hospital Univesitario la Paz, Madrid, Spanien. 2006–2010 Promotion an der Universität Complutense Madrid. 2010–2012 Postdoc am Spanischen Nationalen Zentrum für Biotechnologie, Madrid. 2012–2021 Senior Postdoc an der FU Berlin bei Prof. Dr. J. Rolff. Seit 2022 Forschungsgruppenleiter an der Veterinärmedizinischen Universität Wien.

Jens Rolff Biologiestudium. 1996–1999 Promotion an der TU Braunschweig bei Prof. Dr. G. Rueppell. 1999 Postdoc am Imperial College London, UK, bei Prof. Dr. H. C. J. Godfray. 2000–2003 Postdoc und Marie-Curie Fellow an der University of Sheffield, UK, bei Prof. Dr. M. Siva-Jothy. 2003–2012 NERC Research Fellow, Lecturer und Senior Lecturer, University of Sheffield. Seit 2012 Professor für Evolutionsbiologie an der FU Berlin.

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Rodríguez-Rojas, A., Rolff, J. Antimikrobielle Peptide – Inspiration aus der Natur. Biospektrum 28, 135–137 (2022). https://doi.org/10.1007/s12268-022-1728-3

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  • Published: 28 March 2022

  • Issue Date: March 2022

  • DOI: https://doi.org/10.1007/s12268-022-1728-3

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