Abstract
In this article, the high potential of biocatalysis as a versatile tool to address industrial challenges is illustrated by three examples from our own research, which was done, in part, jointly with companies from the chemical industry. In these examples, biocatalytic processes were deve -loped for products from different industrial segments. In detail, the pro -ducts being obtained by the presented bioprocesses are from the areas of polymer building blocks, lubricant components and pharmaceuticals.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literatur
Arpe H-J (2010) Industrial Organic Chemistry. Wiley-VCH, Weinheim
European Cluster on Catalysis (2016) Science and Technology Roadmap on Catalysis for Europe - A Path to Create a Sustainable Future, http://lib.sioc.ac.cn/tsg_admin/upload/myupload_4622.pdf
Drauz K, May O, Gröger H (Hrsg) (2012) Enzyme Catalysis in Organic Synthesis. Band 1-3, Wiley-VCH, Weinheim
Betke T, Maier M, Gruber-Wölfler H et al. (2018) Biocatalytic production of adiponitrile and related aliphatic linear α,ω-dinitriles. Nat Commun 9:5112
Betke T, Higuchi J, Rommelmann P et al. (2018) Biocatalytic synthesis of nitriles through dehydration of aldoximes: the substrate scope of aldoxime dehydratases. Chembiochem 19:768–779
Betke T, Rommelmann P, Oike K et al. (2017) Cyanide-free and broadly applicable enantioselective synthetic platform for chiral nitriles through a biocatalytic approach. Angew Chem Int Ed Engl 56:12361–12366
Breitbach ZS, Weatherly CA, Woods RM et al. (2014) Development and evaluation of gas and liquid chromatographic methods for the analysis of fatty amines. J Sep Sci 37:558–565
Hinzmann A, Glinski S, Worm M et al. (2019) Enzymatic synthesis of aliphatic nitriles at a substrate loading of up to 1.4 kg/L: a biocatalytic record achieved with a heme protein. J Org Chem 84:4867–4872
Plass C, Hinzmann A, Terhorst M et al. (2019) Approaching bulk chemical nitriles from alkenes: a hydrogen cyanide-free approach through a combination of hydroformylation and biocatalysis. ACS Catal 9:5198–5203
Uthoff F, Löwe L, Harms C et al. (2019) Chemoenzymatic synthesis of a chiral ozanimod key intermediate starting from naphthalene as cheap petrochemical feedstock. J Org Chem 84:4856–4866
Jarvis L (2015) Celgene buys Receptos to capture potential immunology drug. Chem Eng News 93:9
Breuer M, Ditrich K, Habicher T et al. (2004) Industrial methods for the production of optically active intermediates. Angew Chem Int Ed Engl 43:788–824
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Gröger, H. Lösungsansätze entlang der chemischen Wertschöpfungskette. Biospektrum 25, 786–789 (2019). https://doi.org/10.1007/s12268-019-0093-3
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12268-019-0093-3