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Erkennung, Bindung, Signalgebung: Funktionsmoleküle für Biosensoren

  • Wissenschaft · Special: Molekulare Diagnostik
  • Sensor-Aktor-Moleküle
  • Published:
BIOspektrum Aims and scope

Abstract

Diagnostics are essential for detecting infectious agents and the assessment of a disease. In the joint research project “The Lab in a Hankie — Impulse Centre for Integrated Bioanalysis” the complete integration of all necessary processing steps was intended. Work has been done on a new class of sensor-actor molecules integrating detection and signalling and being applicable to complex matrices. Defining binding parts, assembly on a polymer scaffold, enabling signal generation and amplification were central goals of this project.

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Authors and Affiliations

  1. Institutsteil Bioanalytik und Bioprozesse (IZI-BB), Fraunhofer-Institut für Zelltherapie und Immunologie (IZI), Am Mühlenberg 13, D-14476, Potsdam-Golm, Deutschland

    Sebastian Kersting, Sebastian Hoppe & Frank F. Bier

  2. Institut für Biochemie und Biologie, Universität Potsdam, Potsdam, Deutschland

    Sebastian Kersting & Frank F. Bier

Authors
  1. Sebastian Kersting
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  2. Sebastian Hoppe
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  3. Frank F. Bier
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Corresponding author

Correspondence to Frank F. Bier.

Additional information

Sebastian Kersting 2004–2010 Biologiestudium am Karlsruher Institut für Technologie (KIT), am Deutschen Krebsforschungszentrum (DKFZ) Heidelberg und an der Norwegian University of Science and Technology (NTNU), Trondheim. Seit 2010 wissenschaftlicher Mitarbeiter/Doktorand an der Universität Potsdam und am Fraunhofer-Institut für Zelltherapie und Immunologie, Institutsteil Bioanalytik und Bioprozesse (IZI-BB).

Sebastian Hoppe 2003–2009 Biotechnologiestudium an der TU Berlin. 2009–2013 Doktorand am Fraunhofer-Institut für Biomedizinische Technik (IBMT), Potsdam. 2013 Promotion an der TU Berlin. Seit 2013 wissenschaftlicher Mitarbeiter am Fraunhofer-Institut für Zelltherapie und Immunologie, Institutsteil Bioanalytik und Bioprozesse (IZI-BB), Potsdam.

Frank F. Bier Physik- und Mathematikstudium an den Universitäten Münster und Heidelberg. 1989 Promotion. 1989–1993 Postdoc in der Gesellschaft für Biotechnologische Forschung (GBF heute HZI), Braunschweig. 1994–1998 Arbeitsgruppenleiter am Max-Delbrück-Centrum für Molekulare Medizin in Berlin. Seit 1998 in diversen Positionen bei der Fraunhofer-Gesellschaft. Seit 2003 Professur für „Angewandte Bioelektronik und Biochiptechnologie“ an der Universität Potsdam. Seit 2014 Leiter der Abteilung „Bio-systemintegration und Automatisierung“ des Fraunhofer-Instituts für Zelltherapie und Immunologie, Institutsteil Bioanalytik und Bioprozesse (IZI-BB), Potsdam.

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Kersting, S., Hoppe, S. & Bier, F.F. Erkennung, Bindung, Signalgebung: Funktionsmoleküle für Biosensoren. Biospektrum 20, 754–757 (2014). https://doi.org/10.1007/s12268-014-0515-1

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  • DOI: https://doi.org/10.1007/s12268-014-0515-1

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