Abstract
The need to understand the mechanisms of polarized growth in filamentous fungi is greater now than ever before. Many filamentous fungi are severe plant and human pathogens and new antifungal strategies are badly needed to limit their growth. Other filamentous fungi are versatile cell factories used in biotechnology for the production of proteins and metabolites. As their morphology limits the productivity, new leads for strain optimization approaches are sought.
Similar content being viewed by others
Literatur
Meng S, Torto-Alalibo T, Chibucos MC et al. (2009) Common processes in pathogenesis by fungal and oomycete plant pathogens, described with Gene Ontology terms. BMC Microbiol 9(Suppl 1):S7, doi: 10.1186/1471-2180-9-S1-S7
Meyer V (2008) Genetic engineering of filamentous fungi — progress, obstacles and future trends. Biotechnol Adv 26:177–185
Papagianni M (2004) Fungal morphology and metabolite production in submerged mycelial processes. Biotechnol Adv 22:189–259
Driouch H, Hänsch R, Wucherpfennig T et al. (2012) Improved enzyme production by bio-pellets of Aspergillus niger: targeted morphology engineering using titanate microparticles. Biotechnol Bioeng 109:462–471
Meyer V, Arentshorst M, Flitter SJ et al. (2009) Reconstruction of signaling networks regulating fungal morphogenesis by transcriptomics. Eukaryot Cell 8:1677–1691
Jacinto E, Lorberg A (2008) TOR regulation of AGC kinases in yeast and mammals. Biochem J 410:19–37
Meyer V, Minkwitz S, Schütze T et al. (2010) The Aspergillus niger RmsA protein: a node in a genetic network? Commun Integr Biol 3:195–197
Takahara T, Maeda T (2013) Evolutionarily conserved regulation of TOR signaling. J Biochem 154:1–10
Kwon MJ, Arentshorst M, Roos ED et al. (2011) Functional characterization of Rho GTPases in Aspergillus niger uncovers conserved and diverged roles of Rho proteins within filamentous fungi. Mol Microbiol 79:1151–1167
Harris S (2011) Cdc42/Rho GTPases in fungi: variations on a common theme. Mol Microbiol 79:1123–1127
Author information
Authors and Affiliations
Corresponding author
Additional information
Vera Meyer 1989–1996 Biotechnologiestudium an der Universität Sofia, Bulgarien und der TU Berlin. 2001 Promotion an der TU Berlin. 2003, 2005–2006 Forschungsaufenthalte am Imperial College London, UK, und an der Universität Leiden, Niederlande. 2008 Habilitation an der TU Berlin. 2008–2011 Assistenzprofessorin am Fachgebiet Mole — kulare Mikrobiologie und Biotechnologie der Universität Leiden. Seit 2011 Professorin für Angewandte und Molekulare Mikrobiologie an der TU Berlin.
Rights and permissions
About this article
Cite this article
Meyer, V. Morphologische Formfindung in Hyphenpilzen — gleich oder ungleich?. Biospektrum 19, 489–491 (2013). https://doi.org/10.1007/s12268-013-0342-9
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12268-013-0342-9