Abstract
Many fungal pathogens are dimorphic in nature, existing in “yeast” and “hyphal” “forms”. The “transition” between these “forms” is often stimulated and controlled by environmental factors and significant fungal virulence factors. The literature review shows that fungi’s growth, fungal “morphogenesis”, and invasion of the host by fungi are often associated with fungal virulence. The “morphogenesis” of fungal cells generates various “forms” like “yeast”, “hyphal”, and “pseudohyphal” “forms”. The “yeast” and “hyphal” “forms” of the fungi are having certain advantages in invading host and fungal virulence. The three properties of “morphogenesis” in fungal cells are symmetry breaking, polarity maintenance, and depolarization. The equilibrium involving polarity preservation and depolarization produces variety of cell shapes in fungi. This chapter reviews “morphogenesis” of filamentous fungi, role, and their relevance to entomopathogenicity.
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References
Bastos KP, Bailão AM, Borges CL, Faria FP, Felipe MS, Silva MG, Martins WS, Fiúza RB, Pereira M, Soares CM (2007) The transcriptome analysis of early morphogenesis in Paracoccidioides brasiliensis mycelium reveals novel and induced genes potentially associated to the dimorphic process. BMC Microbiol 7:29. https://doi.org/10.1186/1471-2180-7-29
Beilharz VC (1994) Cercosporoid fungi on Australian native plants. PhD thesis, Department of Agriculture, The University of Melbourne
Bellocchio S, Montagnoli C, Bozza S, Gaziano R, Rossi G, Mambula SS, Vecchi A, Mantovani A, Levitz SM, Romani L (2004) The contribution of the Toll-like/IL-1 receptor superfamily to innate and adaptive immunity to fungal pathogens in vivo. J Immunol 172(5):3059–3069. https://doi.org/10.4049/jimmunol.172.5.3059
Beyhan S, Gutierrez M, Voorhies M, Sil A (2013) A temperature-responsive network links cell shape and virulence traits in a primary fungal pathogen. PLoS Biol 11(7):e1001614. https://doi.org/10.1371/journal.pbio.1001614
Borges CL, Bailão AM, Báo SN, Pereira M, Parente JA, de Almeida Soares CM (2011) Genes potentially relevant in the parasitic phase of the fungal pathogen Paracoccidioides brasiliensis. Mycopathologia 171(1):1–9. https://doi.org/10.1007/s11046-010-9349-7
Boyce KJ, Andrianopoulos A (2015) Fungal dimorphism: the switch from hyphae to yeast is a specialized morphogenetic adaptation allowing colonization of a host. FEMS Microbiol Rev 39(6):797–811. https://doi.org/10.1093/femsre/fuv035
Bramhachari PV, Prathyusha A, Sheela GM, Reddy NNR, Berde CV, Yugandhar N (2019) Strategies for disruption of biofilm formation ability and intricate quorum sensing networks in aquaculture vibrio pathogens. In: Implication of quorum sensing and biofilm formation in medicine, agriculture and food industry. Springer, Cham, pp 313–321
Brown GD (2006) Dectin-1: a signalling non-TLR pattern-recognition receptor. Nat Rev Immunol 6(1):33–43. https://doi.org/10.1038/nri1745
Caruso M, Sacco M, Medoff G, Maresca B (1987) Heat shock 70 gene is differentially expressed in Histoplasma capsulatum strains with different levels of thermotolerance and pathogenicity. Mol Microbiol 1(2):151–158. https://doi.org/10.1111/j.1365-2958.1987.tb00507.x
Challa S, Neelapu NRR (2018) Quorum sensing in Helicobacter pylori: role of biofilm and its implications for antibiotic resistance and immune evasion. In: Implication of quorum sensing system in biofilm formation and virulence. Springer, Cham, pp 277–286
Challa S, Neelapu NRR (2019) Phylogenetic trees: applications, construction, and assessment. In: Essentials of bioinformatics, vol 3. Springer, Cham, pp 167–192
Challa S, Sheela GM, Neelapu NRR (2018) Understanding the bacterial biofilm resistance to antibiotics and immune evasion. In: Implication of quorum sensing system in biofilm formation and virulence. Springer, Cham, pp 369–381
Challa S, Dutta T, Bramhachari PV, Reddy NNR (2019a) Quorum sensing and multidrug resistance mechanism in Helicobacter pylori. In: Implication of quorum sensing and biofilm formation in medicine, agriculture and food industry. Springer, Cham, pp 101–119
Challa S, Dutta T, Neelapu NRR (2019b) Fungal white biotechnology applications for food security: opportunities and challenges. In: Recent advancement in white biotechnology through fungi. Springer, Cham, pp 119–148
Challa S, Dutta T, Neelapu NRR (2020) Microbiomes associated with plant growing under the hypersaline habitats and mitigation of salt stress. In: Advances in plant microbiome and sustainable agriculture. Springer, Cham, pp 151–178
Chandler JM, Treece ER, Trenary HR, Brenneman JL, Flickner TJ, Frommelt JL, Oo ZM, Patterson MM, Rundle WT, Valle OV, Kim TD, Walker GR, Cooper CR Jr (2008) Protein profiling of the dimorphic, pathogenic fungus, Penicillium marneffei. Proteome Sci 6:17. https://doi.org/10.1186/1477-5956-6-17
Chang F, Drubin D, Nurse P (1997) cdc12p, a protein required for cytokinesis in fission yeast, is a component of the cell division ring and interacts with profilin. J Cell Biol 137(1):169–182. https://doi.org/10.1083/jcb.137.1.169
Chao LY, Rine J, Marletta MA (2008) Spectroscopic and kinetic studies of Nor1, a cytochrome P450 nitric oxide reductase from the fungal pathogen Histoplasma capsulatum. Arch Biochem Biophys 480(2):132–137. https://doi.org/10.1016/j.abb.2008.09.001
Chen H, Fink GR (2006) Feedback control of morphogenesis in fungi by aromatic alcohols. Genes Dev 20(9):1150–1161. https://doi.org/10.1101/gad.1411806
Cole GT, Samson RA (1979) Patterns of development in conidial fungi. Pitman, London
Corlett M, Chong J, Kokko EG (1976) The ultrastructure of the Spilocaea state of Venturia inaequalis in vivo. Can J Microbiol 22(8):1144–1152. https://doi.org/10.1139/m76-166
Cox GM, Harrison TS, McDade HC, Taborda CP, Heinrich G, Casadevall A, Perfect JR (2003) Superoxide dismutase influences the virulence of Cryptococcus neoformans by affecting growth within macrophages. Infect Immun 71(1):173. https://doi.org/10.1128/IAI.71.1.173-180.2003
da Silva SP, Borges-Walmsley MI, Pereira IS, Soares CM, Walmsley AR, Felipe MS (1999) Differential expression of an hsp70 gene during transition from the mycelial to the infective yeast form of the human pathogenic fungus Paracoccidioides brasiliensis. Mol Microbiol 31(4):1039–1050. https://doi.org/10.1046/j.1365-2958.1999.01236.x
Devi KU, Reineke A, Reddy NNR, Rao CUM, Padmavathi J (2006) Genetic diversity, reproductive biology, and speciation in the entomopathogenic fungus Beauveria bassiana (Balsamo) Vuillemin. Genome 49(5):495–504
Devi UK, Reineke A, Rao UCM, Reddy NRN, Khan APA (2007) AFLP and single-strand conformation polymorphism studies of recombination in the entomopathogenic fungus Nomuraea rileyi. Mycol Res 111(6):716–725
Evangelista M, Blundell K, Longtine MS, Chow CJ, Adames N, Pringle JR, Peter M, Boone C (1997) Bni1p, a yeast formin linking cdc42p and the actin cytoskeleton during polarized morphogenesis. Science 276(5309):118–122. https://doi.org/10.1126/science.276.5309.118
Flavia Popi AF, Lopes JD, Mariano M (2002) GP43 from Paracoccidioides brasiliensis inhibits macrophage functions. An evasion mechanism of the fungus. Cell Immunol 218(1–2):87–94. https://doi.org/10.1016/s0008-8749(02)00576-2
Frazier JA, Field CM (1997) Actin cytoskeleton: are FH proteins local organizers? Curr Biol 7(7):R414–R417. https://doi.org/10.1016/s0960-9822(06)00205-3
Gantner BN, Simmons RM, Canavera SJ, Akira S, Underhill DM (2003) Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2. J Exp Med 197(9):1107–1117. https://doi.org/10.1084/jem.20021787
Gay JL, Martin M (1971) An electron microscopic study of bud development in Saccharomycodes ludwigii and Saccharomyces cerevisiae. Arch Mikrobiol 78(2):145–157. https://doi.org/10.1007/bf00424871
Gimeno CJ, Ljungdahl PO, Styles CA, Fink GR (1992) Unipolar cell divisions in the yeast S. cerevisiae lead to filamentous growth: regulation by starvation and RAS. Cell 68(6):1077–1090. https://doi.org/10.1016/0092-8674(92)90079-r
Goldman GH, dos Reis Marques E, Duarte Ribeiro DC, de Souza Bernardes LA, Quiapin AC, Vitorelli PM, Savoldi M, Semighini CP, de Oliveira RC, Nunes LR, Travassos LR, Puccia R, Batista WL, Ferreira LE, Moreira JC, Bogossian AP, Tekaia F, Nobrega MP, Nobrega FG, Goldman MH (2003) Expressed sequence tag analysis of the human pathogen Paracoccidioides brasiliensis yeast phase: identification of putative homologues of Candida albicans virulence and pathogenicity genes. Eukaryot Cell 2(1):34–48. https://doi.org/10.1128/ec.2.1.34-48.2003
Gonzalez A, Hung CY, Cole GT (2011) Coccidioides releases a soluble factor that suppresses nitric oxide production by murine primary macrophages. Microb Pathog 50(2):100–108. https://doi.org/10.1016/j.micpath.2010.11.006
Gougouli M, Koutsoumanis KP (2012) Modeling germination of fungal spores at constant and fluctuating temperature conditions. Int J Food Microbiol 152(3):153–161. https://doi.org/10.1016/j.ijfoodmicro.2011.07.030
Griffiths DA, Swart HJ (1973) Fine structure of conidia in two species of Seimatosporium. Trans Br Mycol Soc 60(1):123–IN120. https://doi.org/10.1016/S0007-1536(73)80067-1
Hajek AE, St. Leger RJ (1994) Interactions between fungal pathogens and insect hosts. Annu Rev Entomol 39(1):293–322. https://doi.org/10.1146/annurev.en.39.010194.001453
Hammill T (2011) Fine structure of annellophores. III Monotosporella sphaerocephala. Can J Bot 50:581–585. https://doi.org/10.1139/b72-071
Harris SD (2011a) Cdc42/Rho GTPases in fungi: variations on a common theme. Mol Microbiol 79(5):1123–1127. https://doi.org/10.1111/j.1365-2958.2010.07525.x
Harris SD (2011b) Hyphal morphogenesis: an evolutionary perspective. Fungal Biol 115(6):475–484. https://doi.org/10.1016/j.funbio.2011.02.002
Harris SD, Hamer L, Sharpless KE, Hamer JE (1997) The Aspergillus nidulans sepA gene encodes an FH1/2 protein involved in cytokinesis and the maintenance of cellular polarity. EMBO J 16(12):3474–3483. https://doi.org/10.1093/emboj/16.12.3474
Harvey IC (1974) Light and electron microscope observations of conidiogenesis in Pleiochaeta setosa (Kirchn.) Hughes. Protoplasma 82(3):203–221. https://doi.org/10.1007/BF01276308
Holbrook ED, Edwards JA, Youseff BH, Rappleye CA (2011) Definition of the extracellular proteome of pathogenic-phase Histoplasma capsulatum. J Proteome Res 10(4):1929–1943. https://doi.org/10.1021/pr1011697
Hornby JM, Jensen EC, Lisec AD, Tasto JJ, Jahnke B, Shoemaker R, Dussault P, Nickerson KW (2001) Quorum sensing in the dimorphic fungus Candida albicans is mediated by farnesol. Appl Environ Microbiol 67(7):2982–2992. https://doi.org/10.1128/aem.67.7.2982-2992.2001
Hung CY, Xue J, Cole GT (2007) Virulence mechanisms of coccidioides. Ann N Y Acad Sci 1111:225–235. https://doi.org/10.1196/annals.1406.020
Hwang C-S, Rhie G-E, Oh J-H, Huh W-K, Yim H-S, Kang S-O (2002) Copper- and zinc-containing superoxide dismutase (Cu/ZnSOD) is required for the protection of Candida albicans against oxidative stresses and the expression of its full virulence. Microbiology (Reading, England) 148:3705–3713. https://doi.org/10.1099/00221287-148-11-3705
Imamura H, Tanaka K, Hihara T, Umikawa M, Kamei T, Takahashi K, Sasaki T, Takai Y (1997) Bni1p and Bnr1p: downstream targets of the Rho family small G-proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae. EMBO J 16(10):2745–2755. https://doi.org/10.1093/emboj/16.10.2745
Jochová J, Rupeš I, Peberdy JF (1993) Effect of the microtubule inhibitor benomyl on protein secretion in Aspergillus nidulans. Mycol Res 97(1):23–27. https://doi.org/10.1016/S0953-7562(09)81107-6
Jones MD, Forn I, Gadelha C, Egan MJ, Bass D, Massana R, Richards TA (2011) Discovery of novel intermediate forms redefines the fungal tree of life. Nature 474(7350):200–203. https://doi.org/10.1038/nature09984
Jyoti S, Singh DP (2017) Fungi as biocontrol agents in sustainable agriculture. In: Singh JS, Singh DP (eds) Microbes and environmental management. Studium Press, New Delhi, pp 172–194
Kamei K, Brummer E, Clemons KV, Stevens DA (1992) Induction of stress protein synthesis in Histoplasma capsulatum by heat, low pH and hydrogen peroxide. J Med Vet Mycol 30(5):385–393
Klis FM, de Groot P, Hellingwerf K (2001) Molecular organization of the cell wall of Candida albicans. Med Mycol 39(Suppl 1):1–8
Kron SJ, Styles CA, Fink GR (1994) Symmetric cell division in pseudohyphae of the yeast Saccharomyces cerevisiae. Mol Biol Cell 5(9):1003–1022. https://doi.org/10.1091/mbc.5.9.1003
Kummasook A, Pongpom P, Vanittanakom N (2007) Cloning, characterization and differential expression of an hsp70 gene from the pathogenic dimorphic fungus, Penicillium marneffei. DNA Seq 18(5):385–394. https://doi.org/10.1080/10425170701309012
Lalitha P, Reddy NNR, Arunalakshmi K (2011) Decolorization of synthetic dyes by Aspergillus flavus. Bioremed J 15(2):121–132
Lalitha P, Nageswara Rao Reddy N, Sai Baba VK, Shravya K, Arunalakshmi K (2013) Corn cob residues: an ideal substrate for growth and cellulase production by Trichoderma viride. J Bioprocess Technol 97:171–179
Lee SC, Li A, Calo S, Heitman J (2013) Calcineurin plays key roles in the dimorphic transition and virulence of the human pathogenic zygomycete Mucor circinelloides. PLoS Pathog 9(9):e1003625. https://doi.org/10.1371/journal.ppat.1003625
Lin X, Alspaugh JA, Liu H, Harris S (2014) Fungal morphogenesis. Cold Spring Harb Perspect Med 5(2):a019679–a019679. https://doi.org/10.1101/cshperspect.a019679
Lorenz MC, Bender JA, Fink GR (2004) Transcriptional response of Candida albicans upon internalization by macrophages. Eukaryot Cell 3(5):1076–1087. https://doi.org/10.1128/ec.3.5.1076-1087.2004
Manseau L, Calley J, Phan H (1996) Profilin is required for posterior patterning of the Drosophila oocyte. Development 122(7):2109–2116
Marques ER, Ferreira ME, Drummond RD, Felix JM, Menossi M, Savoldi M, Travassos LR, Puccia R, Batista WL, Carvalho KC, Goldman MH, Goldman GH (2004) Identification of genes preferentially expressed in the pathogenic yeast phase of Paracoccidioides brasiliensis, using suppression subtraction hybridization and differential macroarray analysis. Mol Gen Genomics 271(6):667–677. https://doi.org/10.1007/s00438-004-1016-6
Mata J, Nurse P (1998) Discovering the poles in yeast. Trends Cell Biol 8(4):163–167. https://doi.org/10.1016/s0962-8924(98)01224-0
Mendgen K, Hahn M, Deising H (1996) Morphogenesis and mechanisms of penetration by plant pathogenic fungi. Annu Rev Phytopathol 34:367–386. https://doi.org/10.1146/annurev.phyto.34.1.367
Minchiotti G, Gargano S, Maresca B (1992) Molecular cloning and expression of hsp82 gene of the dimorphic pathogenic fungus Histoplasma capsulatum. Biochim Biophys Acta 1131(1):103–107. https://doi.org/10.1016/0167-4781(92)90106-a
Minter DW, Kirk PM, Sutton BC (1982) Holoblastic phialides. Trans Br Mycol Soc 79(1):75–93. https://doi.org/10.1016/S0007-1536(82)80193-9
Mösch HU, Fink GR (1997) Dissection of filamentous growth by transposon mutagenesis in Saccharomyces cerevisiae. Genetics 145(3):671–684
Neelapu NRR, Reineke A, Chanchala UMR, Koduru UD (2009) Molecular phylogeny of asexual entomopathogenic fungi with special reference to Beauveria bassiana and Nomuraea rileyi. Rev Iberoam Micol 26(2):129–145
Neelapu NRR, Dutta T, Challa S (2018) Quorum sensing and its role in agrobacterium-mediated gene transfer. In: Implication of quorum sensing system in biofilm formation and virulence. Springer, Cham, pp 259–275
Nguyen VQ, Sil A (2008) Temperature-induced switch to the pathogenic yeast form of Histoplasma capsulatum requires Ryp1, a conserved transcriptional regulator. Proc Natl Acad Sci 105(12):4880. https://doi.org/10.1073/pnas.0710448105
Nicholls S, Leach MD, Priest CL, Brown AJ (2009) Role of the heat shock transcription factor, Hsf1, in a major fungal pathogen that is obligately associated with warm-blooded animals. Mol Microbiol 74(4):844–861. https://doi.org/10.1111/j.1365-2958.2009.06883.x
Nunes LR, Costa de Oliveira R, Leite DB, da Silva VS, dos Reis Marques E, da Silva Ferreira ME, Ribeiro DC, de Souza Bernardes LA, Goldman MH, Puccia R, Travassos LR, Batista WL, Nóbrega MP, Nobrega FG, Yang DY, de Bragança Pereira CA, Goldman GH (2005) Transcriptome analysis of Paracoccidioides brasiliensis cells undergoing mycelium-to-yeast transition. Eukaryot Cell 4(12):2115–2128. https://doi.org/10.1128/ec.4.12.2115-2128.2005
Padmavathi J, Uma Devi K, Rao C, Reddy N (2003) Telomere fingerprinting for assessing chromosome number, isolate typing and recombination in the entomopathogen Beauveria bassiana. Mycol Res 107(5):572–580
Paes HC, Mello-de-Sousa TM, Fernandes L, Teixeira Mde M, Melo Rde O, Derengowski Lda S, Torres FA, Felipe MS (2011) Characterisation of the heat shock factor of the human thermodimorphic pathogen Paracoccidioides lutzii. Fungal Genet Biol 48(10):947–955. https://doi.org/10.1016/j.fgb.2011.06.005
Papagianni M (2004) Fungal morphology and metabolite production in submerged mycelial processes. Biotechnol Adv 22(3):189–259. https://doi.org/10.1016/j.biotechadv.2003.09.005
Pons N, Sutton BC, Gay JL (1985) Ultrastructure of conidiogenesis in Cercospora beticola. Trans Br Mycol Soc 85(3):405–416. https://doi.org/10.1016/S0007-1536(85)80034-6
Posada FJ, Vega FE (2005) A new method to evaluate the biocontrol potential of single spore isolates of fungal entomopathogens. J Insect Sci 5:37. https://doi.org/10.1093/jis/5.1.37
Puccia R, Vallejo MC, Matsuo AL, Longo LV (2011) The paracoccidioides cell wall: past and present layers toward understanding interaction with the host. Front Microbiol 2:257. https://doi.org/10.3389/fmicb.2011.00257
Rappleye CA, Engle JT, Goldman WE (2004) RNA interference in Histoplasma capsulatum demonstrates a role for alpha-(1,3)-glucan in virulence. Mol Microbiol 53(1):153–165. https://doi.org/10.1111/j.1365-2958.2004.04131.x
Rappleye CA, Eissenberg LG, Goldman WE (2007) Histoplasma capsulatum alpha-(1,3)-glucan blocks innate immune recognition by the beta-glucan receptor. Proc Natl Acad Sci U S A 104(4):1366–1370. https://doi.org/10.1073/pnas.0609848104
Rocco NM, Carmen JC, Klein BS (2011) Blastomyces dermatitidis yeast cells inhibit nitric oxide production by alveolar macrophage inducible nitric oxide synthase. Infect Immun 79(6):2385–2395. https://doi.org/10.1128/iai.01249-10
Roeder A, Kirschning CJ, Rupec RA, Schaller M, Weindl G, Korting HC (2004) Toll-like receptors as key mediators in innate antifungal immunity. Med Mycol 42(6):485–498. https://doi.org/10.1080/13693780400011112
Schmidt A, Hall MN (1998) Signaling to the actin cytoskeleton. Annu Rev Cell Dev Biol 14(1):305–338. https://doi.org/10.1146/annurev.cellbio.14.1.305
Sheela GM, Prathyusha A, Neelapu NRR, Bramhachari PV (2018) Intra- and inter-species communication in microbes: living with complex and sociable neighbors. In: Implication of quorum sensing system in biofilm formation and virulence. Springer, Cham, pp 7–16
Sorais F, Barreto L, Leal JA, Bernabé M, San-Blas G, Niño-Vega GA (2010) Cell wall glucan synthases and GTPases in Paracoccidioides brasiliensis. Med Mycol 48(1):35–47. https://doi.org/10.3109/13693780802713356
Stajich JE, Berbee ML, Blackwell M, Hibbett DS, James TY, Spatafora JW, Taylor JW (2009) The fungi. Curr Biol 19(18):R840–R845. https://doi.org/10.1016/j.cub.2009.07.004
Tavares AH, Silva SS, Dantas A, Campos EG, Andrade RV, Maranhão AQ, Brígido MM, Passos-Silva DG, Fachin AL, Teixeira SM, Passos GA, Soares CM, Bocca AL, Carvalho MJ, Silva-Pereira I, Felipe MS (2007) Early transcriptional response of Paracoccidioides brasiliensis upon internalization by murine macrophages. Microbes Infect 9(5):583–590. https://doi.org/10.1016/j.micinf.2007.01.024
Thirach S, Cooper CR Jr, Vanittanakom P, Vanittanakom N (2007) The copper, zinc superoxide dismutase gene of Penicillium marneffei: cloning, characterization, and differential expression during phase transition and macrophage infection. Med Mycol 45(5):409–417. https://doi.org/10.1080/13693780701381271
Uma Devi K, Nageswara Rao Reddy N, Sridevi D, Sridevi V, Murali Mohan C (2004) Esterase-mediated tolerance to a formulation of the organophosphate insecticide monocrotophos in the entomopathogenic fungus, Beauveria bassiana (Balsamo) Vuill: a promising biopesticide. Pest Manag Sci 60(4):408–412
Valle-Aviles L, Valentin-Berrios S, Gonzalez-Mendez RR, Rodriguez-Del Valle N (2007) Functional, genetic and bioinformatic characterization of a calcium/calmodulin kinase gene in Sporothrix schenckii. BMC Microbiol 7:107. https://doi.org/10.1186/1471-2180-7-107
Vanittanakom N, Pongpom M, Praparattanapan J, Cooper CR, Sirisanthana T (2009) Isolation and expression of heat shock protein 30 gene from Penicillium marneffei. Med Mycol 47(5):521–526. https://doi.org/10.1080/13693780802566358
Walther A, Wendland J (2004) Polarized hyphal growth in Candida albicans requires the Wiskott-Aldrich Syndrome protein homolog Wal1p. Eukaryot Cell 3(2):471–482. https://doi.org/10.1128/ec.3.2.471-482.2004
Wang C (1990) Ultrastructure of percurrently proliferating conidiogenous cells and classification. Stud Mycol 32:49–64
Wasserman S (1998) FH proteins as cytoskeletal organizers. Trends Cell Biol 8(3):111–115. https://doi.org/10.1016/s0962-8924(97)01217-8
Watanabe N, Madaule P, Reid T, Ishizaki T, Watanabe G, Kakizuka A, Saito Y, Nakao K, Jockusch BM, Narumiya S (1997) p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin. EMBO J 16(11):3044–3056. https://doi.org/10.1093/emboj/16.11.3044
Webster J (1984) Ainsworth & Bisby’s Dictionary of the Fungi (including the Lichens), DL Hawksworth, BC Sutton, GC Ainsworth (Eds.), Commonwealth Mycological Institute, Kew (1983), Pp. 412. Price£ 12.50. Trans Br Mycol Soc 83(1):189–190
Webster RH, Sil A (2008) Conserved factors Ryp2 and Ryp3 control cell morphology and infectious spore formation in the fungal pathogen Histoplasma capsulatum. Proc Natl Acad Sci U S A 105(38):14573–14578. https://doi.org/10.1073/pnas.0806221105
Wendland J, Philippsen P (2001) Cell polarity and hyphal morphogenesis are controlled by multiple rho-protein modules in the filamentous ascomycete Ashbya gossypii. Genetics 157(2):601–610
Yadav V, Lekkala MM, Surekha C, Neelapu NRR (2020) Global scenario of advance fungal research in crop protection. In: Agriculturally important fungi for sustainable agriculture. Springer, Cham, pp 313–346
Yang E, Wang G, Woo PC, Lau SK, Chow WN, Chong KT, Tse H, Kao RY, Chan CM, Che X, Yuen KY, Cai JJ (2013) Unraveling the molecular basis of temperature-dependent genetic regulation in Penicillium marneffei. Eukaryot Cell 12(9):1214–1224. https://doi.org/10.1128/ec.00159-13
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Challa, S., Neelapu, N.R.R. (2021). Morphogenesis of Filamentous Fungi: Role and Their Relevance to Entomopathogenicity. In: Villa, T.G., de Miguel Bouzas, T. (eds) Developmental Biology in Prokaryotes and Lower Eukaryotes. Springer, Cham. https://doi.org/10.1007/978-3-030-77595-7_19
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