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Biomolekulare Interaktionen: Manche mögen’s heiß

  • Wissenschaft · Methoden
  • Microscale Thermophoresis
  • Published:
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Abstract

The Microscale Thermophoresis (MST) is a biophysical method to characterize biomolecular interactions in bulk solution. Interaction affinities can be quantified in biological liquids, without immobilization and without a size or mass limitation. Its material consumption is very low and today’s resolvable dissoziation constants range from Kd = 100 pM to Kd = 10 mM.

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Author information

Authors and Affiliations

  1. Nanotemper Technologies GmbH, München, Germany

    Moran Jerabek-Willemsen, Stefan Duhr & Philipp Baaske

  2. NanoTemper Technologies GmbH, Flößergasse 4, D-81369, München, Germany

    Philipp Baaske

Authors
  1. Moran Jerabek-Willemsen
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  2. Stefan Duhr
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  3. Philipp Baaske
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Corresponding author

Correspondence to Philipp Baaske.

Additional information

Moran Jerabek-Willemsen Jahrgang 1976. 2005 Biologiestudium (Diplom), Universität Düsseldorf. 2010 Promotion am Universitätsklinikum Essen. Seit 2010 Applikations-Spezialist bei NanoTemper.

Stefan Duhr Jahrgang 1980. 2004 Biochemiestudium (Diplom), Universität Witten/Herdecke. 2007 Promotion an der LMU München. Seit 2008 Gründer und Geschäftsführer von NanoTemper.

Philipp Baaske Jahrgang 1979. 2005 Physikstudium (Diplom), Universität Bayreuth. Seit 2008 Gründer und Geschäftsführer von NanoTemper. 2010 Promotion LMU München.

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Jerabek-Willemsen, M., Duhr, S. & Baaske, P. Biomolekulare Interaktionen: Manche mögen’s heiß. Biospektrum 18, 30–32 (2012). https://doi.org/10.1007/s12268-012-0139-2

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  • DOI: https://doi.org/10.1007/s12268-012-0139-2

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