Abstract
Probiotics are known to reduce the risk of infective complications and promote gastrointestinal motility after elective abdominal surgery. However, their role in postoperative recovery after peritonitis has not been studied. This prompted us to study the clinical benefits of probiotics in postoperative recovery of patients with gastro-duodenal perforation peritonitis. In this prospective study, 88 operated patients of gastro-duodenal perforation peritonitis were randomised into control and study groups. Surgical procedure and postoperative recovery protocols were standardised in all patients, but the study group received probiotics (Lactobacillus casei strain Shirota). Time to first bowel sound, first flatus, serial white blood cell counts, morbidity, mortality, and hospital stay were compared between the two groups. No significant differences were found between the two groups. The beneficial role of probiotics seen in elective abdominal surgeries could not be demonstrated in cases of gastro-duodenal perforation peritonitis.
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Meena, P.K., Damde, H.K., Mishra, A. et al. Do Probiotics Aid in the Recovery of Gastrointestinal Motility After Surgery for Gastro-duodenal Perforation Peritonitis?. Indian J Surg 85, 1417–1420 (2023). https://doi.org/10.1007/s12262-023-03770-8
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DOI: https://doi.org/10.1007/s12262-023-03770-8