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Postoperative Acute Kidney Injury in Abdominal Operations – a Case Series Analysis

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Abstract

Our study aimed to evaluate the incidence and causative factors for acute kidney injury in abdominal operations. All the abdominal operations performed between April 2018 and December 2020 have been analyzed for various factors associated with acute kidney injury. Acute kidney injury is defined according to acute kidney injury network classification. Categorical variables were evaluated by Chi-square t-test or Fisher’s t-test wherever appropriate and continuous variables by Mann Whitney U test. Statistical analysis was done using SPSS version 23. P < 0.05 was considered statistically significant. Four hundred and three abdominal operations were evaluated. After exclusion, 372 patients were included in the study population. Twenty patients (5.37%) were defined as having acute kidney injury. On univariate analysis, acute kidney injury was associated with open surgery (p = 0.003), intraoperative hypotension (p < 0.001), colorectal surgeries (p < 0.0001), emergency surgery (p = 0.028), Centre of Disease Control grades of surgical wounds (p < 0.001), increased used to blood products (p = 0.001), higher American Society of Anesthesiology grade (p < 0.0001), and increased operative time (p < 0.0001). On multivariate logistic regression analysis, higher American Society of Anesthesiology grade (p < 0.0001) and increased operative time (0.049) independently predicted acute kidney injury. Acute kidney injury was also significantly associated with 90 days mortality (p ≤ 0.0001). Postoperative acute kidney injury was associated with significant mortality in abdominal surgery. Higher American Society of Anesthesiology grades and increased operative time predicted acute kidney injury.

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Abbreviations

ASA:

American society of anesthesiology

AKIN:

Acute kidney injury network

RIFLE:

Risk, Injury, Failure, Loss and End stage

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  1. Shalby Hospitals, Ahmedabad, 380015, India

    Bhavin B. Vasavada & Hardik Patel

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  1. Bhavin B. Vasavada
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  2. Hardik Patel
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Correspondence to Bhavin B. Vasavada.

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Vasavada, B.B., Patel, H. Postoperative Acute Kidney Injury in Abdominal Operations – a Case Series Analysis. Indian J Surg 84, 442–447 (2022). https://doi.org/10.1007/s12262-021-02967-z

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