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Expecting the Unexpected: an Encounter with Primary Neuroendocrine Cancer of the Breast

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Abstract

Primary neuroendocrine carcinoma of the breast (NECB) is a rare disease with an incidence of approximately 1–5%. The World Health Organization classified them as a separate subtype of breast carcinoma. It is often confused with neuroendocrine differentiation of an invasive ductal carcinoma which may lead to an erroneous management, since there are yet no strict management guidelines, for this histological subtype. Due to its histological uniqueness and bizarre biological behaviour, certain subtypes of these cancers are often have a sinister prognosis. We report a single case of a primary small cell carcinoma, a variant of neuroendocrine carcinoma of the breast (NECB) which was managed by with mastectomy and adjuvant chemotherapy.

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Authors and Affiliations

  1. Department of General Surgery, R.G. Kar Medical College and Hospital, 1, Khudiram Bose Sarani, Kolkata, West Bengal, 700004, India

    Shouptik Basu & Ramanuj Mukherjee

Authors
  1. Shouptik Basu
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  2. Ramanuj Mukherjee
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Dr. Shouptik Basu and Dr. Ramanuj Mukherjee have drafted the manuscript, are responsible for the intellectual content, critical insights for the manuscript, and both of them have approved the final version of the published article.

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Correspondence to Ramanuj Mukherjee.

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The authors declare no competing interests.

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Basu, S., Mukherjee, R. Expecting the Unexpected: an Encounter with Primary Neuroendocrine Cancer of the Breast. Indian J Surg 84 (Suppl 3), 816–819 (2022). https://doi.org/10.1007/s12262-021-02954-4

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  • DOI: https://doi.org/10.1007/s12262-021-02954-4

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