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Numerical Study of Bifurcated Blood Flow in Three Different Blood Viscosity Models

三种不同血液黏度模型分叉血流的数值研究

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Abstract

This study aimed to analyze the hemodynamic effects of bifurcated vessels using different blood viscosity models. Three-dimensional models of bifurcated vessels in the popliteal artery were constructed based on CT images, and hemodynamic parameters of the Newtonian, Casson, and two-phase models were calculated by the computational fluid dynamics method. Blood flowed through the popliteal artery. Blood flow velocity changed after the bifurcated vessel, with accelerated blood flow velocity in the anterior tibial artery. A low-velocity vortex region with a region of low wall shear stress (WSS) was generated outside the bifurcated vessel. Local non-Newtonian importance coefficients of great than 1 (i.e., IL > 1) occurred during the cardiac cycle, and IL > 1.75 occurred at the beginning and end of the cycle. Compared with the Casson and two-phase models, the Newtonian model has a larger vortex region and lower WSS. Low-velocity vortex regions and low WSS regions in the bifurcated vessels may contribute to the development of atherosclerosis. Blood exhibited non-Newtonian fluid properties inbifurcated vessels (IL > 1), and the effect of non-Newtonian properties was more pronounced at the beginning and end of heartbeats (IL > 1.75). The Newtonian model predicts a higher risk of atherosclerosis formation and the effect of non-Newtonian properties of blood should be considered in hemodynamic studies. It is necessary to consider the influence of non-Newtonian properties of blood in hemodynamic studies.

摘要

本研究旨在分析不同血液黏度模型分叉血管的血流动力学影响. 基于CT图像构建腘动脉分叉血管三维模型, 通过计算流体力学(CFD)方法计算牛顿模型、 Casson模型和两相模型的血流动力学参数. 血液流经腘动脉分叉血管后血液流速发生改变, 胫前动脉血液流速加快; 分叉血管外侧产生低速涡流区并伴随低壁面切应力(WSS)区域. 在心动周期内局部非牛顿重要性系数 IL > 1, 心动初期和心动末期 IL > 1.75. 与Casson模型和两相模型相比, 牛顿模型的涡流区更大, WSS更低. 分叉血管的低速涡流区和低壁面切应力区可能会导致动脉粥样硬化的产生. 血液在分叉血管表现为非牛顿流体特性(IL > 1), 在心动初期和心动末期非牛顿特性影响显著(IL > 1.75). 牛顿模型预测的动脉粥样硬化形成的风险更高; 血流动力学研究中, 应考虑血液非牛顿特性的影响.

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Authors and Affiliations

  1. School of Mechanical Engineering, Xinjiang University, Urumqi, 830000, China

    Hui Wu  (吴 辉), Rongchang Fu  (富荣昌), Xiaoyu Yang  (杨晓玉), Xianzheng Li  (李现政) & Zhaoyao Wang  (王召耀)

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  1. Hui Wu  (吴 辉)
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  2. Rongchang Fu  (富荣昌)
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  3. Xiaoyu Yang  (杨晓玉)
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  4. Xianzheng Li  (李现政)
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  5. Zhaoyao Wang  (王召耀)
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Correspondence to Rongchang Fu  (富荣昌).

Additional information

Foundation item: the National Natural Science Foundation of China (No. 31460245)

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Wu, H., Fu, R., Yang, X. et al. Numerical Study of Bifurcated Blood Flow in Three Different Blood Viscosity Models. J. Shanghai Jiaotong Univ. (Sci.) 28, 450–458 (2023). https://doi.org/10.1007/s12204-022-2512-8

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  • DOI: https://doi.org/10.1007/s12204-022-2512-8

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