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Perivascular Fat and its Role in Vascular Disease, Insulin Resistance and Diabetes

  • Diabetes + Insulin Resistance (J Robinson, Section Editor)
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Abstract

Perivascular adipose tissue is a visceral fat depot with an anatomical and functional contiguity to the vasculature system. Recent evidence suggests that perivascular adipose tissue could mechanically and functionally affect the vasculature, thereby possibly playing a role in adiposity-related atherosclerosis. Experimental and clinical observations suggest both favorable and unfavorable effects of perivascular fat. This review focuses on the emerging physiological and pathophysiological aspects of the perivascular fat and its role in vascular disease, insulin resistance and diabetes.

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Chengyu Xu and Gianluca Iacobellis declare no conflicts of interest.

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  1. Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Miller School of Medicine, University of Miami, 1400 NW 10th Ave, Dominion Tower suite 805-807, Miami, FL, 33136, USA

    Chengyu Xu & Gianluca Iacobellis

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Xu, C., Iacobellis, G. Perivascular Fat and its Role in Vascular Disease, Insulin Resistance and Diabetes. Curr Cardiovasc Risk Rep 8, 370 (2014). https://doi.org/10.1007/s12170-013-0370-5

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