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FDG-PET/CT findings of autoimmune pancreatitis associated with idiopathic retroperitoneal fibrosis

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Abstract

We report the fluorodeoxyglucose positron emission tomography (FDG-PET)/computed tomography (CT) findings of autoimmune pancreatitis (AIP) associated with idiopathic retroperitoneal fibrosis. A 69-year-old male patient was admitted to our hospital with obstructive jaundice. Six months prior to this admission, he was treated with steroid therapy for retroperitoneal fibrosis. Laboratory data showed that elevated T-bil, C-reactive protein, amylase and immunoglobulin 4, and antinuclear antibodies were positive. Clinical history, laboratory data, CT image, and magnetic resonance imaging led to a diagnosis of autoimmune pancreatitis. To investigate the inflammatory activity, FDG-PET/CT was undertaken. FDG-PET/CT demonstrated diffuse intense FDG uptake in the enlarged pancreas and diffuse mild uptake in the region of the abdominal aorta-bilateral iliac arteries. A dilated right renal pelvis and upper ureter, corresponding to hydronephrosis probably caused by retroperitoneal fibrosis, were shown. An FDG-PET/CT was useful to evaluate inflammatory activity and morphological imaging, and supported our diagnosis of AIP and retroperitoneal fibrosis.

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References

  1. Members of the Criteria Committee for Autoimmune Pancreatitis of the Japan Pancreas Society. J Jpn Pancreas Soc 2002;17:587

    Google Scholar 

  2. T Ito I Nakano S Koyanagi T Miyahara Y Migita K Ogoshi et al. (1997) ArticleTitleAutoimmune pancreatitis as a new clinical entity: three cases of autoimmune pancreatitis with effective steroid therapy Dig Dis Sci 42 1458–68 Occurrence Handle9246047 Occurrence Handle10.1023/A:1018862626221 Occurrence Handle1:STN:280:DyaK2szovVyitg%3D%3D

    Article  PubMed  CAS  Google Scholar 

  3. K Okazaki K Uchida M Matsushita M Takaoka (2005) ArticleTitleAutoimmune pancreatitis Intern Med 44 1215–23 Occurrence Handle16415540 Occurrence Handle10.2169/internalmedicine.44.1215 Occurrence Handle1:CAS:528:DC%2BD28XhslOiu7g%3D

    Article  PubMed  CAS  Google Scholar 

  4. A Chutaputti MI Burrell JL Boyer (1995) ArticleTitlePseudotumor of the pancreas associated with retroperitoneal fibrosis: a dramatic response to corticosteroid therapy Am J Gastroenterol 90 1155–8 Occurrence Handle7611217 Occurrence Handle1:STN:280:DyaK2MzjsFGquw%3D%3D

    PubMed  CAS  Google Scholar 

  5. A Horiuchi S Kawa T Akamatsu (1998) ArticleTitleCharacteristic pancreatic duct appearance in autoimmune chronic pancreatitis: a case report and review of the Japanese literature Am J Gastroenterol 93 260–3 Occurrence Handle9468255 Occurrence Handle10.1111/j.1572-0241.1998.00260.x Occurrence Handle1:STN:280:DyaK1c7islOksQ%3D%3D

    Article  PubMed  CAS  Google Scholar 

  6. T Higashi T Saga Y Nakamoto T Ishimori K Fujimoto R Doi et al. (2003) ArticleTitleDiagnosis of pancreatic cancer using fluorine-18 fluorodeoxyglucose positron emission tomography (FDG PET): usefulness and limitations in “clinical reality” Ann Nucl Med 17 261–79 Occurrence Handle12932109 Occurrence Handle10.1007/BF02988521

    Article  PubMed  Google Scholar 

  7. Y Nakamoto T Saga T Ishimori T Higashi M Mamede K Okazaki et al. (2000) ArticleTitleFDG-PET of autoimmune-related pancreatitis: preliminary results Eur Nucl Med 27 1835–8 Occurrence Handle10.1007/s002590000370 Occurrence Handle1:STN:280:DC%2BD3M7ltlagtw%3D%3D

    Article  CAS  Google Scholar 

  8. M Nakajo S Jinnouchi M Noguchi K Uozumi H Tanabe R Tateno (2007) ArticleTitleFDG PET and PET/CT monitoring of autoimmune pancreatitis associated with extrapancreatic autoimmune disease Clin Nucl Med 32 282–5 Occurrence Handle17413574 Occurrence Handle10.1097/01.rlu.0000257295.12017.ab

    Article  PubMed  Google Scholar 

  9. K Natohara LJ Burgart D Yadav S Chari TC Smyrk (2003) ArticleTitleIdiopathic chronic pancreatitis with periductal lymphoplasmacytic infiltration: clinicopathologic features of 35 cases Am J Sur Pathol 27 1119–27 Occurrence Handle10.1097/00000478-200308000-00009

    Article  Google Scholar 

  10. LA Forstrom WL Dunn BP Mullan JC Hung VJ Lowe LM Thorson (2002) ArticleTitleBiodistribution and dosimetry of [18F]fluorodeoxyglucose labeled leukocytes in normal human subjects Nucl Med Commun 23 721–5 Occurrence Handle12124476 Occurrence Handle10.1097/00006231-200208000-00004 Occurrence Handle1:CAS:528:DC%2BD38Xmslejsrc%3D

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Radiology, Graduate School of Medicine, University of Tokushima, 3-18-15 Kuramoto-cho, Tokushima, 770-8503, Japan

    Hideki Otsuka, Naomi Morita, Kyo Yamashita & Hiromu Nishitani

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  1. Hideki Otsuka
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  2. Naomi Morita
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  3. Kyo Yamashita
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  4. Hiromu Nishitani
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Correspondence to Hideki Otsuka.

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Otsuka, H., Morita, N., Yamashita, K. et al. FDG-PET/CT findings of autoimmune pancreatitis associated with idiopathic retroperitoneal fibrosis. Ann Nucl Med 21, 593–596 (2007). https://doi.org/10.1007/s12149-007-0069-0

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  • DOI: https://doi.org/10.1007/s12149-007-0069-0

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