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Kaposiform Hemangioendothelioma of the Oral Cavity: A Rare Tumor with an Unusual Location

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Abstract

Kaposiform hemangioendothelioma is a rare neoplasm with intermediate malignant behavior, mainly affecting infants and children. Involvement head and neck is uncommon, and there are only four cases reported in the oral cavity and oropharynx. Microscopically, it is characterized by a vascular proliferation permeated by spindle-to-ovoid cells resembling Kaposi sarcoma. Immunohistochemically, the tumor is positive for CD31, CD34 and negative for D2-40. Herein we present a rare case of intraoral Kaposiform hemangioendothelioma in a 10-year-old boy.

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Authors and Affiliations

  1. Oral Pathology, Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil

    Thayná M. de Lima Morais & Oslei P. de Almeida

  2. Molecular Pathology Area, Faculty of Dentistry, Universidad de la República, Montevideo, Uruguay

    Celeste Sánchez-Romero

  3. Brazilian Association of Dentistry, Governador Valadares, Minas Gerais, Brazil

    Luciano Ribeiro

  4. Oral Diagnosis, Department of Dentistry, Federal University of Juiz de Fora, Governador Valadares, Brazil

    Daniele S. Faé, Francielle S. Verner & Sibele Nascimento de Aquino

Authors
  1. Thayná M. de Lima Morais
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  2. Celeste Sánchez-Romero
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  3. Luciano Ribeiro
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  4. Daniele S. Faé
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  5. Francielle S. Verner
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  6. Oslei P. de Almeida
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  7. Sibele Nascimento de Aquino
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Contributions

All authors contributed to the case report. Clinical and surgical evaluation was performed by LR and DSF. Radiographic analysis was realized by FSV. Data collection and histopathological analysis were performed by TMdLM, OPdA, SNdA and CS-R. The first draft of the manuscript was written by TMdLM and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Sibele Nascimento de Aquino.

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Morais, T.M.d., Sánchez-Romero, C., Ribeiro, L. et al. Kaposiform Hemangioendothelioma of the Oral Cavity: A Rare Tumor with an Unusual Location. Head and Neck Pathol 15, 1421–1425 (2021). https://doi.org/10.1007/s12105-021-01316-6

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  • DOI: https://doi.org/10.1007/s12105-021-01316-6

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