Abstract
Skin metastases are rare complications of internal malignancies, and most commonly arise from primary lung carcinoma (Brownstein and Helwig in Arch Dermatol 105:82–68, 1972). Metastatic cutaneous lesions have not previously been documented to arise within other skin tumours. We report our experience of a solitary pulmonary adenocarcinoma metastasis that arose within a pre-existing basal cell carcinoma in a patient with undiagnosed lung cancer. Immunohistochemistry was invaluable in confirming both the metastatic nature of the secondary skin lesion and its site of origin.
References
Brownstein MH, Helwig EB. Patterns of cutaneous metastasis. Arch Dermatol. 1972;105:82–6.
Chang YL, Lee YC, Liao WY, et al. The utility and limitation of thyroid transcription factor -1 protein in primary and metastatic pulmonary neoplasms. Lung Cancer. 2004;44:149–57.
Niu HL, Pasha TL, Pawel BR, et al. Thyroid transcription factor-1 expression in normal gynecologic tissues and its potential significance. Int J Gynecol Pathol. 2009;28:301–7.
Kubba LA, McCluggage WG, Liu J, et al. Thyroid Transcription Factor-1 expression in ovarian epithelial neoplasms. Mod Pathol. 2008;21:485–90.
Coslett LM, Katlic MR. Lung cancer with skin metastasis. Chest. 1990;97:757–75.
Lookingbill DP, Spangler N, Helm KF. Cutaneous metastases in patients with metastatic carcinoma: a retrospective study of 4020 patients. J Am Acad Dermatol. 1993;29:228–33.
Dreizen S, Dhingra HM, Chiuten DF, et al. Cutaneous and subcutaneous metastases of lung cancer. Clinical characteristics. Postgrad Med J. 1986;80:111–6.
Petraki C, Vaslamatzis M, Argyrakos T, et al. Tumor to tumor metastasis: report of two cases and review of the literature. Int J Surg Pathol, 2003;127-135.
Conflict of Interest
There are no conflicts of interests.
Author information
Authors and Affiliations
Corresponding author
Electronic supplementary material
Below is the link to the electronic supplementary material.
Rights and permissions
About this article
Cite this article
Carey, E., Jones, S.D., Griffiths, P. et al. Metastatic Pulmonary Adenocarcinoma Deposit Arising Within a Cutaneous Basal Cell Carcinoma: A Case Report. Head and Neck Pathol 5, 410–412 (2011). https://doi.org/10.1007/s12105-011-0263-1
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12105-011-0263-1