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1H, 15N, and 13C chemical shift assignments of the calflagin Tb24 flagellar calcium binding protein of Trypanosoma brucei

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Abstract

Flagellar calcium binding proteins are expressed in a variety of trypanosomes and are potential drug targets for Chagas disease and African sleeping sickness. We report complete NMR chemical shift assignments of the flagellar calcium binding protein calflagin Tb24 of Trypanosoma brucei. (BMRB no. 18011).

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Acknowledgments

We thank Jerry Dallas for technical support and help with NMR experiments. Work supported by NIH grants (EY012347) to J.B.A and (RR11973) to the UC Davis NMR facility.

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Authors and Affiliations

  1. Department of Chemistry, University of California, Davis, CA, 95616, USA

    Xianzhong Xu & James B. Ames

  2. Departments of Pathology and Microbiology–Immunology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA

    Cheryl L. Olson & David M. Engman

Authors
  1. Xianzhong Xu
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  2. Cheryl L. Olson
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  3. David M. Engman
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  4. James B. Ames
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Correspondence to James B. Ames.

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Xu, X., Olson, C.L., Engman, D.M. et al. 1H, 15N, and 13C chemical shift assignments of the calflagin Tb24 flagellar calcium binding protein of Trypanosoma brucei . Biomol NMR Assign 7, 9–12 (2013). https://doi.org/10.1007/s12104-012-9366-1

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