Skip to main content
SpringerLink
Log in

Intravenous immunoglobulin therapy of lupus pneumonitis

  • Clinical Brief
  • Published:
The Indian Journal of Pediatrics Aims and scope Submit manuscript

Abstract

Acute lupus pneumonitis in an 11-year-old girl with lupus nephritis is reported. Chest radiograph and arterial blood gas parameters were suggestive of Acute Respiratory Distress Syndrome (ARDS). Definitive pulmonary infection was excluded by investigations and poor clinical response to antibiotics. The respiratory worsening warranted ventilatory support with very high pressures. A trial of intravenous immunoglobulin was given following which there was improvement in the ventilatory requirements by 36 hours. The child was successfully weaned off ventilator and discharged from ICU by day 7. The role of intravenous immunoglobulin during acute life threatening pulmonary emergencies in a case of SLE prompted this clinical brief.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Francioni C, Galeazzi M, Fioravanti A, Gelli R, Megale F, Marcolongo R. Long-term i.v. Ig treatment in systemic lupus erythematosus. Clin Exp Rheumatol 1994; 12: 163–168.

    PubMed  CAS  Google Scholar 

  2. Casidy JT. Systematic Lupus Erythematosus. In Cassidy JT, Petty RE, Ronald LM, Carol LB, eds. Textbook of Pediatric Rheumatology, 5th edn. Philadelphia; WB Saunders Co., 2005; 342–343.

    Google Scholar 

  3. Williams FMK, Chinn S, Hughes GRV, Leach RM. Critical illness in systemic lupus erythematosus and the antiphospholipid syndrome. Ann Rheum Dis 2002; 61: 420–421.

    Article  Google Scholar 

  4. Sivestris F, Cafforio P, Dammacco F. Pathogenic anti-DNA idiotype-reactive IgG in Intravenous Immunoglobulin preparation. Clin Exp Immunol 1994; 97: 19–25.

    Article  Google Scholar 

  5. Evans MJ, Suenaga R, Abdou NI. Detection and purification of antiidiotypic antibody against anti-DNA in intravenous immune globulin. J Clin Immunopathol 1991; 11: 291–295.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, 605 006, India

    G. Chetan, S. Mahadevan, Kikon Sulanthung & P. Narayanan

Authors
  1. G. Chetan
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. S. Mahadevan
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Kikon Sulanthung
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. P. Narayanan
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to S. Mahadevan.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Chetan, G., Mahadevan, S., Sulanthung, K. et al. Intravenous immunoglobulin therapy of lupus pneumonitis. Indian J Pediatr 74, 1032–1033 (2007). https://doi.org/10.1007/s12098-007-0190-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12098-007-0190-z

Key words

Search

Navigation