Skip to main content
SpringerLink
Log in

Intracranial arteriovenous malformation with maternal carbamazepine use

  • Clinical Brief
  • Published:
The Indian Journal of Pediatrics Aims and scope Submit manuscript

Abstract

1½ month old child born to primigravida mother on prolonged carbamazepine therapy presented with recurrent seizures. The child had abnormal facies and was diagnosed to be having arteriovenous malformation with intracranial hemorrhage on neuroimaging. This case suggests that development of arteriovenous malformation in a child with maternal carbamazepine therapy may occur as a part of clinical profile of ‘fetal anticonvulsant syndrome’.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Crawford P. Best practice guidelines for the management of women with epilepsy. Epilepsia 2005; 46(Suppl 9): 117–124.

    Article  PubMed  Google Scholar 

  2. Yerby MS, Leavitt A, EricKson B, McComick KB, Loewenson RB, Sells CJ et al. Antiepileptic drugs and the development of congenital anomalies. Neurology 1992; 42: 132–140.

    PubMed  CAS  Google Scholar 

  3. Artama M, Auvineu A, Raudaskoski T, Isojarvi I, Isojarvi J. Antiepileptic drug use of women with epilepsy and congenital malformations in offspring. Neurology 2005; 64: 1874–1878.

    Article  PubMed  CAS  Google Scholar 

  4. Jones KL, Lacro RV, Johnson KA, Adams J. Pattern of malformations in the children of women treated with carbamazepine during pregnancy. N Engl J Med 1989; 320: 1661–1666.

    Article  PubMed  CAS  Google Scholar 

  5. Gupta G, Bansal A, Singh M. Antenatal Carbamazepine use associated with d-TGA and ASD. Indian Pediatr 2002; 39: 101–102.

    PubMed  Google Scholar 

  6. Halem RHA. The nervous system: Intracerebral hemorrhage. In Behrman, Kliegman, Jenson, eds. Nelson Textbook of Pediatrics. Philadelphia; WB Saunders Co; 1999; 1856.

    Google Scholar 

  7. Lindhout D, Hoppener RJ, Meinardi H. Teratogenicity of antiepileptic drug combinations with special emphasis on epoxidation (of carbamazepine). Epilepsia 1984; 25: 77–83.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pediatrics, University College of Medical Sciences and GTB Hospital, Delhi, A16/F1, Dilshad Garden, 110095, India

    Manish Narang, Dheeraj Shah & Gupta Natasha

  2. Department of Radiology, Aruna Asif Ali Government Hospital, Delhi, India

    Gupta Natasha

Authors
  1. Manish Narang
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Dheeraj Shah
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Gupta Natasha
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Manish Narang.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Narang, M., Shah, D. & Natasha, G. Intracranial arteriovenous malformation with maternal carbamazepine use. Indian J Pediatr 74, 85–86 (2007). https://doi.org/10.1007/s12098-007-0035-9

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12098-007-0035-9

Key words

Search

Navigation