Alonzi T, Middleton G, Wyatt S, Buchman V, Betz UA, Muller W, Musiani P, Poli V, Davies AM (2001) Role of STAT3 and PI 3-kinase/Akt in mediating the survival actions of cytokines on sensory neurons. Mol Cell Neurosci 18:270–282
CAS
Article
PubMed
Google Scholar
Armstrong SJ, Wiberg M, Terenghi G, Kingham PJ (2008) Laminin activates NF-kappaB in Schwann cells to enhance neurite outgrowth. Neurosci Lett 439:42–46
CAS
Article
PubMed
Google Scholar
Askvig JM, Leiphon LJ, Watt JA (2012) Neuronal activity and axonal sprouting differentially regulate CNTF and CNTF receptor complex in the rat supraoptic nucleus. Exp Neurol 233:243–252
PubMed Central
CAS
Article
PubMed
Google Scholar
Askvig JM, Lo DY, Sudbeck AW, Behm KE, Leiphon LJ, Watt JA (2013) Inhibition of the Jak-STAT pathway prevents CNTF-mediated survival of axotomized oxytocinergic magnocellular neurons in organotypic cultures of the rat supraoptic nucleus. Exp Neurol 240:75–87
PubMed Central
CAS
Article
PubMed
Google Scholar
Asnaghi L, Calastretti A, Bevilacqua A, D’Agnano I, Gatti G, Canti G, Delia D, Capaccioli S, Nicolin A (2004) Bcl-2 phosphorylation and apoptosis activated by damaged microtubules require mTOR and are regulated by Akt. Oncogene 23:5781–5791
CAS
Article
PubMed
Google Scholar
Bain J, Plater L, Elliott M, Shpiro N, Hastie CJ, McLauchlan H, Klevernic I, Arthur JS, Alessi DR, Cohen P (2007) The selectivity of protein kinase inhibitors: a further update. Biochem J 408:297–315
PubMed Central
CAS
Article
PubMed
Google Scholar
Ballif BA, Blenis J (2001) Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals. Cell Growth Differ: Mol Biol J Am Assoc Cancer Res 12:397–408
CAS
Google Scholar
Ben-Barak Y, Russell JT, Whitnall MH, Ozato K, Gainer H (1985) Neurophysin in the hypothalamo-neurohypophysial system. I. Production and characterization of monoclonal antibodies. J Neurosci: Off J Soc Neurosci 5:81–97
CAS
Google Scholar
Bennett BL, Sasaki DT, Murray BW, O’Leary EC, Sakata ST, Xu W, Leisten JC, Motiwala A, Pierce S, Satoh Y, Bhagwat SS, Manning AM, Anderson DW (2001) SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci U S A 98:13681–13686
PubMed Central
CAS
Article
PubMed
Google Scholar
Bilsland J, Rigby M, Young L, Harper S (1999) A rapid method for semi-quantitative analysis of neurite outgrowth from chick DRG explants using image analysis. J Neurosci Methods 92:75–85
CAS
Article
PubMed
Google Scholar
Bonni A, Frank DA, Schindler C, Greenberg ME (1993) Characterization of a pathway for ciliary neurotrophic factor signaling to the nucleus. Science 262:1575–1579
CAS
Article
PubMed
Google Scholar
Cagnon L, Braissant O (2009) CNTF protects oligodendrocytes from ammonia toxicity: intracellular signaling pathways involved. Neurobiol Dis 33:133–142
CAS
Article
PubMed
Google Scholar
Cargnello M, Roux PP (2011) Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases. Microbiol Mol Biol Rev: MMBR 75:50–83
PubMed Central
CAS
Article
PubMed
Google Scholar
Chen L, Liu L, Luo Y, Huang S (2008) MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis. J Neurochem 105:251–261
CAS
Article
PubMed
Google Scholar
Chen S, Xu Y, Xu B, Guo M, Zhang Z, Liu L, Ma H, Chen Z, Luo Y, Huang S, Chen L (2011) CaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell death. J Neurochem 119:1108–1118
PubMed Central
CAS
Article
PubMed
Google Scholar
Chicoine LM, Bahr BA (2007) Excitotoxic protection by polyanionic polysaccharide: evidence of a cell survival pathway involving AMPA receptor-MAPK Interactions. J Neurosci Res 85:294–302
CAS
Article
PubMed
Google Scholar
Cuenda A, Rousseau S (2007) p38 MAP-kinases pathway regulation, function and role in human diseases. Biochim Biophys Acta 1773:1358–1375
CAS
Article
PubMed
Google Scholar
Davis S, Aldrich TH, Stahl N, Pan L, Taga T, Kishimoto T, Ip NY, Yancopoulos GD (1993) LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor. Science 260:1805–1808
CAS
Article
PubMed
Google Scholar
Decker T, Kovarik P (2000) Serine phosphorylation of STATs. Oncogene 19:2628–2637
CAS
Article
PubMed
Google Scholar
Dhanasekaran DN, Reddy EP (2008) JNK signaling in apoptosis. Oncogene 27:6245–6251
PubMed Central
CAS
Article
PubMed
Google Scholar
Dolcet X, Soler RM, Gould TW, Egea J, Oppenheim RW, Comella JX (2001) Cytokines promote motoneuron survival through the Janus kinase-dependent activation of the phosphatidylinositol 3-kinase pathway. Mol Cell Neurosci 18:619–631
CAS
Article
PubMed
Google Scholar
English JM, Cobb MH (2002) Pharmacological inhibitors of MAPK pathways. Trends Pharmacol Sci 23:40–45
CAS
Article
PubMed
Google Scholar
Frank SJ, Yi W, Zhao Y, Goldsmith JF, Gilliland G, Jiang J, Sakai I, Kraft AS (1995) Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor. J Biol Chem 270:14776–14785
CAS
Article
PubMed
Google Scholar
Gallagher D, Gutierrez H, Gavalda N, O’Keeffe G, Hay R, Davies AM (2007) Nuclear factor-kappaB activation via tyrosine phosphorylation of inhibitor kappaB-alpha is crucial for ciliary neurotrophic factor-promoted neurite growth from developing neurons. J Neurosci 27:9664–9669
PubMed Central
CAS
Article
PubMed
Google Scholar
Giordano V, De Falco G, Chiari R, Quinto I, Pelicci PG, Bartholomew L, Delmastro P, Gadina M, Scala G (1997) Shc mediates IL-6 signaling by interacting with gp130 and Jak2 kinase. J Immunol 158:4097–4103
CAS
PubMed
Google Scholar
Gold MR, Duronio V, Saxena SP, Schrader JW, Aebersold R (1994) Multiple cytokines activate phosphatidylinositol 3-kinase in hemopoietic cells. Association of the enzyme with various tyrosine-phosphorylated proteins. J Biol Chem 269:5403–5412
CAS
PubMed
Google Scholar
Greenwood SM, Bushell TJ (2010) Astrocytic activation and an inhibition of MAP kinases are required for proteinase-activated receptor-2-mediated protection from neurotoxicity. J Neurochem 113:1471–1480
CAS
PubMed
Google Scholar
Gurney ME, Yamamoto H, Kwon Y (1992) Induction of motor neuron sprouting in vivo by ciliary neurotrophic factor and basic fibroblast growth factor. J Neurosci: Off J Soc Neurosci 12:3241–3247
CAS
Google Scholar
Guthrie KM, Woods AG, Nguyen T, Gall CM (1997) Astroglial ciliary neurotrophic factor mRNA expression is increased in fields of axonal sprouting in deafferented hippocampus. J Comp Neurol 386:137–148
CAS
Article
PubMed
Google Scholar
Gutierrez H, Hale VA, Dolcet X, Davies A (2005) NF-kappaB signalling regulates the growth of neural processes in the developing PNS and CNS. Development 132:1713–1726
CAS
Article
PubMed
Google Scholar
House SB, Thomas A, Kusano K, Gainer H (1998) Stationary organotypic cultures of oxytocin and vasopressin magnocellular neurones from rat and mouse hypothalamus. J Neuroendocrinol 10:849–861
CAS
Article
PubMed
Google Scholar
House SB, Rusnak M, Liu XH, Youle RJ, Gainer H (2006) Bcl-xL and caspase inhibition increase the survival of rat oxytocin and vasopressin magnocellular neurons in organotypic culture. Exp Neurol 200:267–271
CAS
Article
PubMed
Google Scholar
House SB, Li C, Yue C, Gainer H (2009) Effects of ciliary neurotrophic factor and leukemia inhibiting factor on oxytocin and vasopressin magnocellular neuron survival in rat and mouse hypothalamic organotypic cultures. J Neurosci Methods 178:128–133
PubMed Central
CAS
Article
PubMed
Google Scholar
Hresko RC, Mueckler M (2005) mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes. J Biol Chem 280:40406–40416
CAS
Article
PubMed
Google Scholar
Ihle JN, Kerr IM (1995) Jaks and Stats in signaling by the cytokine receptor superfamily. Trends Genet: TIG 11:69–74
CAS
Article
PubMed
Google Scholar
Ip NY, Nye SH, Boulton TG, Davis S, Taga T, Li Y, Birren SJ, Yasukawa K, Kishimoto T, Anderson DJ et al (1992) CNTF and LIF act on neuronal cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp130. Cell 69:1121–1132
CAS
Article
PubMed
Google Scholar
Ip NY, McClain J, Barrezueta NX, Aldrich TH, Pan L, Li Y, Wiegand SJ, Friedman B, Davis S, Yancopoulos GD (1993) The alpha component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development. Neuron 10:89–102
CAS
Article
PubMed
Google Scholar
Itoh K, Konishi A, Nomura S, Mizuno N, Nakamura Y, Sugimoto T (1979) Application of coupled oxidation reaction to electron microscopic demonstration of horseradish peroxidase: cobalt-glucose oxidase method. Brain Res 175:341–346
CAS
Article
PubMed
Google Scholar
Jaworski J, Spangler S, Seeburg DP, Hoogenraad CC, Sheng M (2005) Control of dendritic arborization by the phosphoinositide-3′-kinase-Akt-mammalian target of rapamycin pathway. J Neurosci: Off J Soc Neurosci 25:11300–11312
CAS
Article
Google Scholar
Jover-Mengual T, Zukin RS, Etgen AM (2007) MAPK signaling is critical to estradiol protection of CA1 neurons in global ischemia. Endocrinology 148:1131–1143
PubMed Central
CAS
Article
PubMed
Google Scholar
Kane LP, Shapiro VS, Stokoe D, Weiss A (1999) Induction of NF-kappaB by the Akt/PKB kinase. Curr Biol: CB 9:601–604
CAS
Article
PubMed
Google Scholar
Karassek S, Berghaus C, Schwarten M, Goemans CG, Ohse N, Kock G, Jockers K, Neumann S, Gottfried S, Herrmann C, Heumann R, Stoll R (2010) Ras homolog enriched in brain (Rheb) enhances apoptotic signaling. J Biol Chem 285:33979–33991
PubMed Central
CAS
Article
PubMed
Google Scholar
Kassen SC, Thummel R, Campochiaro LA, Harding MJ, Bennett NA, Hyde DR (2009) CNTF induces photoreceptor neuroprotection and Muller glial cell proliferation through two different signaling pathways in the adult zebrafish retina. Exp Eye Res 88:1051–1064
CAS
Article
PubMed
Google Scholar
Kato H, Nakajima S, Saito Y, Takahashi S, Katoh R, Kitamura M (2012) mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathway. Cell Death Differ 19:310–320
PubMed Central
CAS
Article
PubMed
Google Scholar
Kobayashi M, Nagata S, Kita Y, Nakatsu N, Ihara S, Kaibuchi K, Kuroda S, Ui M, Iba H, Konishi H, Kikkawa U, Saitoh I, Fukui Y (1997) Expression of a constitutively active phosphatidylinositol 3-kinase induces process formation in rat PC12 cells. Use of Cre/loxP recombination system. J Biol Chem 272:16089–16092
CAS
Article
PubMed
Google Scholar
Kwon YW, Gurney ME (1994) Systemic injections of ciliary neurotrophic factor induce sprouting by adult motor neurons. Neuroreport 5:789–792
CAS
Article
PubMed
Google Scholar
Lee JC, Laydon JT, McDonnell PC, Gallagher TF, Kumar S, Green D, McNulty D, Blumenthal MJ, Heys JR, Landvatter SW et al (1994) A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 372:739–746
CAS
Article
PubMed
Google Scholar
Loy B, Apostolova G, Dorn R, McGuire VA, Arthur JS, Dechant G (2011) p38alpha and p38beta mitogen-activated protein kinases determine cholinergic transdifferentiation of sympathetic neurons. J Neurosci: Off J Soc Neurosci 31:12059–12067
CAS
Article
Google Scholar
Luo JM, Cen LP, Zhang XM, Chiang SW, Huang Y, Lin D, Fan YM, van Rooijen N, Lam DS, Pang CP, Cui Q (2007) PI3K/akt, JAK/STAT and MEK/ERK pathway inhibition protects retinal ganglion cells via different mechanisms after optic nerve injury. Eur J Neurosci 26:828–842
Article
PubMed
Google Scholar
Lutticken C, Wegenka UM, Yuan J, Buschmann J, Schindler C, Ziemiecki A, Harpur AG, Wilks AF, Yasukawa K, Taga T et al (1994) Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130. Science 263:89–92
CAS
Article
PubMed
Google Scholar
Marwarha G, Dasari B, Prabhakara JP, Schommer J, Ghribi O (2010) beta-Amyloid regulates leptin expression and tau phosphorylation through the mTORC1 signaling pathway. J Neurochem 115:373–384
PubMed Central
CAS
Article
PubMed
Google Scholar
Miller AL, Garza AS, Johnson BH, Thompson EB (2007) Pathway interactions between MAPKs, mTOR, PKA, and the glucocorticoid receptor in lymphoid cells. Cancer Cell Int 7:3
PubMed Central
Article
PubMed
Google Scholar
Muller A, Hauk TG, Leibinger M, Marienfeld R, Fischer D (2009) Exogenous CNTF stimulates axon regeneration of retinal ganglion cells partially via endogenous CNTF. Mol Cell Neurosci 41:233–246
Article
PubMed
Google Scholar
Nagata S (1999) Fas ligand-induced apoptosis. Annu Rev Genet 33:29–55
CAS
Article
PubMed
Google Scholar
Nave BT, Ouwens M, Withers DJ, Alessi DR, Shepherd PR (1999) Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation. Biochem J 344(Pt 2):427–431
PubMed Central
CAS
Article
PubMed
Google Scholar
Oh H, Fujio Y, Kunisada K, Hirota H, Matsui H, Kishimoto T, Yamauchi-Takihara K (1998) Activation of phosphatidylinositol 3-kinase through glycoprotein 130 induces protein kinase B and p70 S6 kinase phosphorylation in cardiac myocytes. J Biol Chem 273:9703–9710
CAS
Article
PubMed
Google Scholar
Ohnishi M, Katsuki H, Izumi Y, Kume T, Takada-Takatori Y, Akaike A (2010) Mitogen-activated protein kinases support survival of activated microglia that mediate thrombin-induced striatal injury in organotypic slice culture. J Neurosci Res 88:2155–2164
CAS
Article
PubMed
Google Scholar
O’Neill LA, Kaltschmidt C (1997) NF-kappa B: a crucial transcription factor for glial and neuronal cell function. Trends Neurosci 20:252–258
Article
PubMed
Google Scholar
Oyesiku NM, Wigston DJ (1996) Ciliary neurotrophic factor stimulates neurite outgrowth from spinal cord neurons. J Comp Neurol 364:68–77
CAS
Article
PubMed
Google Scholar
Ozog MA, Modha G, Church J, Reilly R, Naus CC (2008) Co-administration of ciliary neurotrophic factor with its soluble receptor protects against neuronal death and enhances neurite outgrowth. J Biol Chem 283:6546–6560
CAS
Article
PubMed
Google Scholar
Park K, Luo JM, Hisheh S, Harvey AR, Cui Q (2004) Cellular mechanisms associated with spontaneous and ciliary neurotrophic factor-cAMP-induced survival and axonal regeneration of adult retinal ganglion cells. J Neurosci: Off J Soc Neurosci 24:10806–10815
CAS
Article
Google Scholar
Peterson WM, Wang Q, Tzekova R, Wiegand SJ (2000) Ciliary neurotrophic factor and stress stimuli activate the Jak-STAT pathway in retinal neurons and glia. J Neurosci: Off J Soc Neurosci 20:4081–4090
CAS
Google Scholar
Phulwani NK, Esen N, Syed MM, Kielian T (2008) TLR2 expression in astrocytes is induced by TNF-alpha- and NF-kappa B-dependent pathways. J Immunol 181:3841–3849
PubMed Central
CAS
Article
PubMed
Google Scholar
Read DE, Gorman AM (2009) Involvement of Akt in neurite outgrowth. Cell Mol Life Sci: CMLS 66:2975–2984
CAS
Article
PubMed
Google Scholar
Rhee KD, Goureau O, Chen S, Yang XJ (2004) Cytokine-induced activation of signal transducer and activator of transcription in photoreceptor precursors regulates rod differentiation in the developing mouse retina. J Neurosci: Off J Soc Neurosci 24:9779–9788
CAS
Article
Google Scholar
Romashkova JA, Makarov SS (1999) NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling. Nature 401:86–90
CAS
Article
PubMed
Google Scholar
Rusnak M, Gainer H (2005) Differential effects of forskolin on tyrosine hydroxylase gene transcription in identified brainstem catecholaminergic neuronal subtypes in organotypic culture. Eur J Neurosci 21:889–898
Article
PubMed
Google Scholar
Rusnak M, House SB, Arima H, Gainer H (2002) Ciliary neurotrophic factor increases the survival of magnocellular vasopressin and oxytocin neurons in rat supraoptic nucleus in organotypic cultures. Microsc Res Tech 56:101–112
CAS
Article
PubMed
Google Scholar
Rusnak M, House SB, Gainer H (2003) Long-term effects of ciliary neurotrophic factor on the survival of vasopressin magnocellular neurones in the rat supraoptic nucleus in vitro. J Neuroendocrinol 15:933–939
CAS
Article
PubMed
Google Scholar
Sango K, Yanagisawa H, Komuta Y, Si Y, Kawano H (2008) Neuroprotective properties of ciliary neurotrophic factor for cultured adult rat dorsal root ganglion neurons. Histochem Cell Biol 130:669–679
CAS
Article
PubMed
Google Scholar
Sarbassov DD, Guertin DA, Ali SM, Sabatini DM (2005) Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307:1098–1101
CAS
Article
PubMed
Google Scholar
Schuster B, Kovaleva M, Sun Y, Regenhard P, Matthews V, Grotzinger J, Rose-John S, Kallen KJ (2003) Signaling of human ciliary neurotrophic factor (CNTF) revisited. The interleukin-6 receptor can serve as an alpha-receptor for CTNF. J Biol Chem 278:9528–9535
CAS
Article
PubMed
Google Scholar
Shahar T, House SB, Gainer H (2004) Neural activity protects hypothalamic magnocellular neurons against axotomy-induced programmed cell death. J Neurosci: Off J Soc Neurosci 24:6553–6562
CAS
Article
Google Scholar
Siegel SG, Patton B, English AW (2000) Ciliary neurotrophic factor is required for motoneuron sprouting. Exp Neurol 166:205–212
CAS
Article
PubMed
Google Scholar
Simon CM, Jablonka S, Ruiz R, Tabares L, Sendtner M (2010) Ciliary neurotrophic factor-induced sprouting preserves motor function in a mouse model of mild spinal muscular atrophy. Hum Mol Genet 19:973–986
CAS
Article
PubMed
Google Scholar
Sole C, Dolcet X, Segura MF, Gutierrez H, Diaz-Meco MT, Gozzelino R, Sanchis D, Bayascas JR, Gallego C, Moscat J, Davies AM, Comella JX (2004) The death receptor antagonist FAIM promotes neurite outgrowth by a mechanism that depends on ERK and NF-kapp B signaling. J Cell Biol 167:479–492
PubMed Central
CAS
Article
PubMed
Google Scholar
Stahl N, Farruggella TJ, Boulton TG, Zhong Z, Darnell JE Jr, Yancopoulos GD (1995) Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors. Science 267:1349–1353
CAS
Article
PubMed
Google Scholar
Stoppini L, Buchs PA, Muller D (1991) A simple method for organotypic cultures of nervous tissue. J Neurosci Methods 37:173–182
CAS
Article
PubMed
Google Scholar
Su C, Underwood W, Rybalchenko N, Singh M (2011) ERK1/2 and ERK5 have distinct roles in the regulation of brain-derived neurotrophic factor expression. J Neurosci Res 89:1542–1550
CAS
Article
PubMed
Google Scholar
Symes A, Lewis S, Corpus L, Rajan P, Hyman SE, Fink JS (1994) STAT proteins participate in the regulation of the vasoactive intestinal peptide gene by the ciliary neurotrophic factor family of cytokines. Mol Endocrinol 8:1750–1763
CAS
PubMed
Google Scholar
Thoreen CC, Sabatini DM (2009) Rapamycin inhibits mTORC1, but not completely. Autophagy 5:725–726
CAS
Article
PubMed
Google Scholar
Thoreen CC, Kang SA, Chang JW, Liu Q, Zhang J, Gao Y, Reichling LJ, Sim T, Sabatini DM, Gray NS (2009) An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1. J Biol Chem 284:8023–8032
PubMed Central
CAS
Article
PubMed
Google Scholar
Thoreen CC, Chantranupong L, Keys HR, Wang T, Gray NS, Sabatini DM (2012) A unifying model for mTORC1-mediated regulation of mRNA translation. Nature 485:109–113
PubMed Central
CAS
Article
PubMed
Google Scholar
Tibbles LA, Woodgett JR (1999) The stress-activated protein kinase pathways. Cell Mol Life Sci: CMLS 55:1230–1254
CAS
Article
PubMed
Google Scholar
Trimarchi T, Pachuau J, Shepherd A, Dey D, Martin-Caraballo M (2009) CNTF-evoked activation of JAK and ERK mediates the functional expression of T-type Ca2+ channels in chicken nodose neurons. J Neurochem 108:246–259
PubMed Central
CAS
Article
PubMed
Google Scholar
Ulenkate HJ, Kaal EC, Gispen WH, Jennekens FG (1994) Ciliary neurotrophic factor improves muscle fibre reinnervation after facial nerve crush in young rats. Acta Neuropathol 88:558–564
CAS
Article
PubMed
Google Scholar
Vutskits L, Bartanusz V, Schulz MF, Kiss JZ (1998) Magnocellular vasopressinergic neurons in explant cultures are rescued from cell death by ciliary neurotrophic factor and leukemia inhibiting factor. Neuroscience 87:571–582
CAS
Article
PubMed
Google Scholar
Vutskits L, Gascon E, Kiss JZ (2003) Removal of PSA from NCAM affects the survival of magnocellular vasopressin- and oxytocin-producing neurons in organotypic cultures of the paraventricular nucleus. Eur J Neurosci 17:2119–2126
CAS
Article
PubMed
Google Scholar
Wang JM, Liu L, Brinton RD (2008) Estradiol-17beta-induced human neural progenitor cell proliferation is mediated by an estrogen receptor beta-phosphorylated extracellularly regulated kinase pathway. Endocrinology 149:208–218
PubMed Central
CAS
Article
PubMed
Google Scholar
Watt JA, Bone S, Pressler M, Cranston HJ, Paden CM (2006) Ciliary neurotrophic factor is expressed in the magnocellular neurosecretory system of the rat in vivo: evidence for injury- and activity-induced upregulation. Exp Neurol 197:206–214
CAS
Article
PubMed
Google Scholar
Watt JA, Lo D, Cranston HJ, Paden CM (2009) CNTF receptor alpha is expressed by magnocellular neurons and expression is upregulated in the rat supraoptic nucleus during axonal sprouting. Exp Neurol 215:135–141
PubMed Central
CAS
Article
PubMed
Google Scholar
Winston LA, Hunter T (1995) JAK2, Ras, and Raf are required for activation of extracellular signal-regulated kinase/mitogen-activated protein kinase by growth hormone. J Biol Chem 270:30837–30840
CAS
Article
PubMed
Google Scholar
Winston LA, Hunter T (1996) Intracellular signalling: putting JAKs on the kinase MAP. Curr Biol: CB 6:668–671
CAS
Article
PubMed
Google Scholar
Wright MC, Cho WJ, Son YJ (2007) Distinct patterns of motor nerve terminal sprouting induced by ciliary neurotrophic factor vs. botulinum toxin. J Comp Neurol 504:1–16
Article
PubMed
Google Scholar
Xia K, Mukhopadhyay NK, Inhorn RC, Barber DL, Rose PE, Lee RS, Narsimhan RP, D’Andrea AD, Griffin JD, Roberts TM (1996) The cytokine-activated tyrosine kinase JAK2 activates Raf-1 in a p21ras-dependent manner. Proc Natl Acad Sci U S A 93:11681–11686
PubMed Central
CAS
Article
PubMed
Google Scholar
Xu JJ, Chen EY, Lu CL, He C (2009) Recombinant ciliary neurotrophic factor promotes nerve regeneration and induces gene expression in silicon tube-bridged transected sciatic nerves in adult rats. J Clin Neurosci: Off J Neurosurg Soc Australas 16:812–817
CAS
Article
Google Scholar
Xu B, Chen S, Luo Y, Chen Z, Liu L, Zhou H, Chen W, Shen T, Han X, Chen L, Huang S (2011) Calcium signaling is involved in cadmium-induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network. PLoS One 6:e19052
PubMed Central
CAS
Article
PubMed
Google Scholar
Zamin LL, Dillenburg-Pilla P, Argenta-Comiran R, Horn AP, Simao F, Nassif M, Gerhardt D, Frozza RL, Salbego C (2006) Protective effect of resveratrol against oxygen-glucose deprivation in organotypic hippocampal slice cultures: Involvement of PI3-K pathway. Neurobiol Dis 24:170–182
CAS
Article
PubMed
Google Scholar
Zhou H, Huang S (2010) The complexes of mammalian target of rapamycin. Curr Protein Pept Sci 11:409–424
PubMed Central
CAS
Article
PubMed
Google Scholar