Abstract
The most common plasticizer, phthalates, are facing stricter regulations due to their omnipresence and possible effects on human health, and environment. But high cost, lack of application range, and unknown long-term effects of non-phthalate alternatives make the scenario puzzling.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Suggested Reading
A H Tullo, Plasticizer MakersWant a Piece of the Phthalates Pie, Chemical and Engineering News, Vol.93, No.25, pp.16–18, 2015.
http://www.pvc.org/en/p/history
DOI: 10.1098/rstb.2008.0304
L G Krauskopf, How About Alternatives to Phthalate Plasticizers? J. of Vinyl and Additive Tech., Vol.9, No.4, pp. 159–171, 2003.
http://www.plasticisers.org/en_GB/plasticisers
J D Meeker et al., Phthalates and Other Additives in Plastics: Human Exposure and Associated Health Outcomes, Phil. Trans. R. Soc. B, Vol.364, pp.2097–2113, 2009.
http://www.sustainableproduction.org/downloads/PhthalateAlternatives-January2011.pdf
http://www.cdc.gov/exposurereport/pdf/fourthreport.pdf
E D Hond, et al., First Steps Towards Harmonized Human Biomonitoring in Europe: Demonstration Project to Perform Human Biomonitoring on a European Scale, Env. Health Perspect., Vol.123, No.3, pp.255–263, 2015.
S K Ritter, Phthalates’ Structural Truths, C&En, Vol.93, No.25, pp.19–20, 2015.
R Hauser et al., Phthalates and Human Health, Occup. Environ. Med., Vol.62, pp.806–818, 2005.
https://www.cpsc.gov/en/Business–Manufacturing/Business-Education /Business-Guidance/Phthalates-Information/
S L Plonait et al., Exposure of Newborn Infants to di-(2-ethylhexyl)-phthalate and 2-ethylhexanoic acid Following Exchange Transfusion with Polyvinylchloride Catheters, Transfusion, Vol.33, No.7, pp.598–605, 1993.
Keith Y et al., Peroxisome Proliferation Due to di (2-ethylhexyl) adipate, 2-ethylhexanol and 2-ethylhexanoic acid, Arch. Toxicol., Vol.66, pp.321–326, 1992.
R H Hinton et al., Effects of Phthalic Acid Esters on the Liver and Thyroid, Env. Health Persp., Vol.70, pp.195–210, 1986.
P K Seth, Hepatic Effects of Phthalate Esters, Env. Health Pers., Vol.45, pp.27–34, 1982.
M Larsson, Associations Between Indoor Environmental Factors and Parental-Reported Autistic Spectrum Disorders in Children 6–8 Years of Age, Neurotoxicology, Vol.30, No.5, pp.822–31, 2009.
http://www.chemanager-online.com/en/topics/chemicals-distribution /phthalates-and-their-alternatives
http://www.ecocenter.org/healthy-stuff/reports/vinyl-oor-tiles /Flooring phthalate hazards
http://saferchemicals.org/newsroom/new-study-finds-toxic-chemicalswidespread-in-ooring-sold-by-top-retailers/
https://www.greenbiz.com/article/home-depot-leads-chemical-cleanup-ooring
A H Tullo, Cutting Out Phthalates, C&En, Vol.83, No.46, pp.29–31, 2005.
Author information
Authors and Affiliations
Corresponding author
Additional information
Abhijit Ghosh is a postdoctoral fellow at Brigham Young University. He has earned his PhD in Biomedical Sciences: Health and Environmental Chemistry from Oakland University in 2014. His primary research interest focuses on instrumentation and method development for various gas chromatographic techniques.
Rights and permissions
About this article
Cite this article
Ghosh, A. Phthalate puzzle. Reson 22, 691–696 (2017). https://doi.org/10.1007/s12045-017-0512-z
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12045-017-0512-z