Abstract
The low-density lipoprotein receptor (LDLR), one of the best characterized cell-surface receptors, mediates cholesterol homeostasis and other functions in mammals. The members of the LDLR superfamily are structurally related and characterized by distinct functional domains. Insect lipoprotein receptor is called lipophorin receptor (LpR) and belongs to the LDLR superfamily. Here, we review the structural and functional aspects of lipophorin receptors.
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(left) G Ravikumar is a senior scientist in the Seribiotech Research Laboratory, Central Silk Board, Bangalore. His research interests include cloning and characterization of novel genes, signal transduction, diagnostic methods in silkworms, use of silk proteins for biomedical applications and transgenic insects. He is also interested in improving science education in India.
(right) N B Vijayaprakash is the Ex-Director of Seribiotech Research Laboratory, Central Silk Board, Bangalore. His research interests are reproductive physiology and developmental biology of silkworms, and use of silk in industrial applications.
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Ravikumar, G., Vijayaprakash, N.B. Lipophorin receptor: The insect lipoprotein receptor. Reson 18, 748–755 (2013). https://doi.org/10.1007/s12045-013-0096-1
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DOI: https://doi.org/10.1007/s12045-013-0096-1