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The major players in adaptive immunity

2. Cell-mediated immunity

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Abstract

Our immune system, by and large, does a fine job in protecting us from opportunistic and infectious microbes, potential carcinogens and allergens. It is therefore crucial to understand the organization of the immune network. This article focuses on some important features and key players involved in adaptive immune response. The first part of the article dealt with the humoral immune response mediated mainly by immunoglobulins produced by the B cells. The second part deals with T cells, the Major Histocompatibility Complex (MHC)-encoded molecules, and Recombination Activating Genes (RAG) responsible for generating diverse B-cell receptors (BCR) and T-cell receptors (TCR). With the advent of newer and smarter infectious agents, it is important to understand the working of the immune network as more research in this area may facilitate the development of better protective strategies.

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Authors and Affiliations

  1. Dipankar Nandi’s laboratory, Bangalore, India

    Asma Ahmed & Banishree Saha

  2. Shantiniketan, WB, India

    Anand Patwardhan

  3. M S University, Baroda, India

    Shwetha Shivaprasad

  4. Department of Biochemistry, Indian Institute of Science, Bangalore, 560 012, India

    Dipankar Nandi

Authors
  1. Asma Ahmed
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  2. Banishree Saha
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  3. Anand Patwardhan
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  4. Shwetha Shivaprasad
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  5. Dipankar Nandi
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Correspondence to Dipankar Nandi.

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Ahmed, A., Saha, B., Patwardhan, A. et al. The major players in adaptive immunity. Reson 14, 610–621 (2009). https://doi.org/10.1007/s12045-009-0067-8

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  • DOI: https://doi.org/10.1007/s12045-009-0067-8

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