Abstract
An efficient and direct protocol for the preparation of 12-aryl-8,9,10,12-tetrahydro-benzo[a]xanthen-11-one derivatives employing a three-component one-pot reaction of aryl aldehydes, 2-naphthol and cyclic 1,3-dicarbonyl compounds in the presence of a catalytic amount of cyanuric chloride (2,4,6-trichloro-1,3,5-triazine, TCT) under solvent-free conditions is described. The desired products are obtained in high yields with short reaction times.
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Zhang, ZH., Zhang, P., Yang, SH. et al. Multicomponent, solvent-free synthesis of 12-aryl-8,9,10,12-tetrahydrobenzo[a]-xanthen-11-one derivatives catalysed by cyanuric chloride. J Chem Sci 122, 427–432 (2010). https://doi.org/10.1007/s12039-010-0049-0
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DOI: https://doi.org/10.1007/s12039-010-0049-0