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Preparation of myoglobin-imprinted polymer with a new sulphoxide monomer on the surface of foam-graphene/nano Au via eATRP

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Abstract

Molecular-imprinted polymers (MIPs) are generally considered as substituents for natural antibodies. MIPs synthesis needs to select appropriate functional monomers. Because of its strong interaction with the template, antibody–antigen complexes can be formed before polymerization. In this paper, myoglobin (Mb)-imprinted polymers with a new sulphoxide monomer (2-(methylsulphonyl) ethyl acrylate, MSEA) as functional monomers were successfully prepared via electrochemically mediated atom transfer radical polymerization (eATRP). At the same time, to solve the problems of low selectivity and large template size limitations, the Mb-imprinted polymers were prepared on the surface of Au electrode decorated with three-dimensional foam graphene (FG) and nano Au (nAu). Cyclic voltammetry, electrochemical impedance spectroscopy, scanning electron microscope and X-ray photoelectron spectroscopy were used to characterize the Au electrode modified with Mb-imprinted polymer (Au/FG/nAu/MIPMSEA). The prepared Au/FG/nAu/MIPMSEA electrode was used as an electrochemical sensor to detect Mb. The results of experiments showed that the proposed biosensor had good selectivity, reproducibility, repeatability and stability. The linear response range was from 1.0 × 10−12 to 1.0 × 10−1 mg·l−1, and the detection limit was 1.21 × 10−13 mg·l−1 (S/N = 3). Compared with other methods for detecting Mb, the sensor had a wider detection range and lower detection limit.

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References

  1. Liu Y, Liu J, Tang H, Liu J, Xu B, Yu F et al 2015 Sens. Actuators B Chem. 206 647

    Article  Google Scholar 

  2. Gijs R, Gideon W, Vanessa T, Alexander W, Patrick W and Tanja J 2019 Macromolecules 52 2304

    Article  Google Scholar 

  3. Moreira Felismina T C, Dutra Rosa A F, Noronha João P C and Sales M G F 2013 Electrochim. Acta 107 481

    Article  Google Scholar 

  4. Xu L, Li J and Zhang J 2020 Analyst 145 3245

    Article  CAS  Google Scholar 

  5. Huang J, Zhang X and Liu S 2011 J. Appl. Electrochem. 41 1323

    Article  CAS  Google Scholar 

  6. Zhu Q, Karsten Haupt and Dietnar Knopp 2002 Anal. Chim. Acta 468 217

    Article  CAS  Google Scholar 

  7. Sergeyeva T A, Piletsky S A and Brovko A A 1999 Anal. Chim. Acta 392 105

    Article  CAS  Google Scholar 

  8. Karsten H and Klaus M 2000 Chem. Rev. 100 2495

    Article  Google Scholar 

  9. Muldoon Mark T and Stanker Larry H 1997 Anal. Chem. 69 803

    Article  Google Scholar 

  10. Wang J, Cormack Peter A G and Sherrington David C 2003 Angew. Chem. Int. Ed 115 5494

    Article  Google Scholar 

  11. Chen L, Wang X and Lu W 2016 Chem. Soc. Rev. 45 2137

    Article  CAS  Google Scholar 

  12. Karim K, Breton F and Rouillon R 2005 Adv. Drug Deliv. Rev. 57 1795

    Article  CAS  Google Scholar 

  13. Sun Y, Feng X and Hu J 2020 Anal. Bioanal. Chem. 412 983

    Article  CAS  Google Scholar 

  14. Jia J, Jiang Q and Zhao A 2016 Synthesis 48 421

    CAS  Google Scholar 

  15. Kang M, Kim B and Woo H Y 2011 Proc. Spie 7908 790809

    Article  Google Scholar 

  16. Lee I, Kim G W and Yang M 2016 ACS Appl. Mater. Interfaces 8 302

    Article  Google Scholar 

  17. Li S, Chung H S and Simakova A 2017 Biomacromolecules 18 475

    Article  CAS  Google Scholar 

  18. Mackenzie M C, Shrivats A R and Konkolewicz D 2015 Biomacromolecules 16 236

    Article  CAS  Google Scholar 

  19. El Mohtadi F, Richard D and Turhan Y 2019 Int. J. Mol. Sci. 20 4583

    Article  CAS  Google Scholar 

  20. Choong C L, Bendall J S and Milne W I 2009 Biosens. Bioelectron. 25 652

    Article  CAS  Google Scholar 

  21. Sun C, Li Z and Zhong X 2018 J. Electrochem. Soc. 165 F24

    Article  CAS  Google Scholar 

  22. Yang G, Lee C and Kim J 2013 J. Electrochem. Soc. 160 B160

    Article  CAS  Google Scholar 

  23. Yang J, Qi G and Bao R 2018 Energy Storage Mater. 13 88

    Article  Google Scholar 

  24. Libu M, Núnez C and Wenting D 2018 Nano Energy 51 604

    Article  Google Scholar 

  25. Xu S, Zhang C and Jiang S 2019 Sens. Actuators B Chem. B 284 125

    Article  CAS  Google Scholar 

  26. Motia S, Bouchikhi B and Bari N 2021 Talanta 223 121689

    Article  CAS  Google Scholar 

  27. Wu Y, Ali M R K, Chen K C, Fang N and El-Sayed M A 2019 Nano Today 24 120

    Article  CAS  Google Scholar 

  28. Li H, Chai W and Henkelman G 2019 J. Mater. Chem. A 7 23868

    Article  CAS  Google Scholar 

  29. Ma Z, Qiu Y and Huang Y 2015 RSC Adv. 5 79456

    Article  CAS  Google Scholar 

  30. Song B, Zhou S, Guo D, Li P, Jiang L, Zhang J et al 2020 ACS Sustain Chem. Eng. 2 1311

    Article  Google Scholar 

  31. Shahrokhinia A, Scanga R A, Biswas P and Reuther J 2021 Macromolecules 54 1441

    Article  CAS  Google Scholar 

  32. Wei X, Li X and Husson S M 2005 Macromolecules 6 1113

    CAS  Google Scholar 

  33. Ramakers G, Wackers G and Trouillet V 2019 Macromolecules 52 2304

    Article  CAS  Google Scholar 

  34. Li D, Fu Y and Qin M 2013 Adv. Mater. Res. 734–737 2108

    Article  Google Scholar 

  35. Chmielarz P, Krys P and Park S 2015 Polymer 71 143

    Article  CAS  Google Scholar 

  36. Pollard J, Rifaie-Graham O, Raccio S, Davey A, Balog S and Bruns N 2020 Anal. Chem. 92 1162

    Article  CAS  Google Scholar 

  37. Sun Y, Du H, Lan Y, Wang W and Liang Y 2016 Biosens. Bioelectron. 77 894

    Article  CAS  Google Scholar 

  38. Sun Y, Feng X, Hu J, Bo S, Zhang J and Wang W 2020 Anal. Bioanal. Chem. 412 983

    Article  CAS  Google Scholar 

  39. Sun Y, Zhang J, Li J, Zhao M and Liu Y 2017 RSC Adv. 7 28461

    Article  CAS  Google Scholar 

  40. Sun Y, Li S, Yang Y, Feng X, Wang W, Liu Y et al 2019 J. Electroanal. Chem. 848 113346

    Article  CAS  Google Scholar 

  41. Sun Y, Du H, Deng Y, Lan Y and Feng C 2016 J. Solid State Electrochem. 20 105

    Article  CAS  Google Scholar 

  42. Mahmoudian M R, Basirun W J and Alias Y 2016 RSC Adv. 6 36459

    Article  CAS  Google Scholar 

  43. Liu Y, Liu J and Tang H 2015 Sens. Actuators B Chem. 206 647

    Article  Google Scholar 

  44. Tan X, Hu Q, Wu J, Li X, Li P, Yu H et al 2015 Sens. Actuators B Chem. 220 216

    Article  CAS  Google Scholar 

  45. Luo J, Jiang S and Liu X 2014 Sens. Actuators B Chem. 203 782

    Article  CAS  Google Scholar 

  46. Xiong L, Liang H, Wang R and Chen L 2010 J. Polym. Res. 18 1017

    Article  Google Scholar 

  47. Seo J H, Yang R and Brzezinski J Z 2014 Adv. Mater. 21 1006

    Article  Google Scholar 

  48. Ledeuil J, Uhart A and Samantha S 2014 Nanoscale 6 11130

    Article  CAS  Google Scholar 

  49. Du T, Li B and Wang X 2016 Angew. Chem. Int. Ed. 55 4260

    Article  CAS  Google Scholar 

  50. Ma J, Chen H, Liu D, Ji N and Zong G 2013 Mater. Sci. Eng. C 33 1

    Article  CAS  Google Scholar 

  51. Li Y, Li Y and Yang Y 2011 Bioelectrochemistry 82 112

    Article  CAS  Google Scholar 

  52. Zhao W, Li B and Xu S 2019 J. Mater. Chem. B 7 2311

    Article  CAS  Google Scholar 

  53. Ma Y, Hu Q and Liu C 2020 J. Electroanal. Chem. 862 113994

    Article  CAS  Google Scholar 

  54. Piloto A, Ribeiro D and Rodrigues S 2019 Sens. Actuators B Chem. 304 127343

    Article  Google Scholar 

  55. Zhao W, Li B, Xu S, Zhu Y and Liu X 2020 Anal. Chim. Acta 1117 25

    Article  CAS  Google Scholar 

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Acknowledgements

We gratefully acknowledge the financial support from the Science Research Project of Education Department of Liaoning Province (No. LQ2019022), Liaoning BaiQianWan Talents Program (No. 2020921109), High-end Research Incubation Scheme of Liaoning Normal University (GD20L001), the National Natural Science Foundation of China (No. 21304041) and the Innovative Training Program of College Students in Liaoning Normal University (Nos. 201910165215, 202010165158).

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Authors and Affiliations

  1. School of Chemistry and Chemical Engineering, Liaoning Normal University, Dalian, 116029, China

    Zhen Han, Yuxi Zhou, Yifei Yang, Yu Sun, Yuping Wang, Yifan Wang & Yue Sun

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  1. Zhen Han
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  2. Yuxi Zhou
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  3. Yifei Yang
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  4. Yu Sun
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  5. Yuping Wang
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  6. Yifan Wang
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  7. Yue Sun
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Correspondence to Yue Sun.

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Han, Z., Zhou, Y., Yang, Y. et al. Preparation of myoglobin-imprinted polymer with a new sulphoxide monomer on the surface of foam-graphene/nano Au via eATRP. Bull Mater Sci 45, 58 (2022). https://doi.org/10.1007/s12034-021-02640-x

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  • DOI: https://doi.org/10.1007/s12034-021-02640-x

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