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The role of nutrition in harnessing the immune system: a potential approach to prevent cancer

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Abstract

Cancer is a vital barrier to increase the life expectancy and the foremost cause of death globally. The initial diagnosis and proper management of cancer can expand the survival rate of individuals. This review provides an in-depth investigation of cancer causes symptoms, types of cancer, and worldwide distribution of cancer. The relation between nutrition (i.e., various food items) and cancer is also emphasized to offer a framework of nutrition management in different cancer types. The microbiota is closely associated with the occurrence of cancer. Thus, genomics of intestinal microbes and nutrigenomics have been discussed based on the reported meta-analysis studies. A dramatic increase in cancer rates has been observed due to intake of alcohol, microbial infections, and deficiency of nutrition. Malnutrition is a substantial problem in cancer patients linked with improper treatment and increased morbidity. The detail studies of cancer and nutrigenomics are an eminent approach to comprehend the relation between microbes and the consumption of certain food types which can further reduce the cancer risk. The incorporation of specific nutrients and probiotics improved the gut microbial health, increased life expectancy, and also decreased the incidence of tumorigenesis in individuals.

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Funding

This research was supported by construction of the double first-class project (Grant No. 561119201), Lanzhou University, China, El-Sayed Salama.

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Authors and Affiliations

  1. Pingliang Rehabilitation Center Hospital, No. 23 Taitong Road, Kongtong District, Pingliang, 744000, People’s Republic of China

    Hu Xiaogang

  2. MOE, Key Laboratory of Cell Activities and Stress Adaptations, Lanzhou University, Lanzhou City, 730000, Gansu Province, People’s Republic of China

    Monika Sharma, Irfan saif, Gohar Ali & Xiangkai Li

  3. Department of Occupational and Environmental Health, School of Public Health, Lanzhou University, Lanzhou City, 730000, Gansu Province, People’s Republic of China

    Monika Sharma, Irfan saif, Gohar Ali & El-Sayed Salama

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HX contributed to visualization, investigation, data curation, formal analysis, and writing of the Original Draft. MS contributed to investigation, visualization, data curation, formal analysis, and writing, reviewing, & editing. Is contributed to visualization, reviewing, and formal analysis. GA contributed to visualization and formal analysis. XL contributed to conceptualization, resources, data curation, validation, writing, reviewing, & editing of the manuscript. El-SS contributed to conceptualization, supervision, resources, data curation, validation, visualization, formal analysis, writing, reviewing, & editing of the manuscript, funding acquisition, and project administration.

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Xiaogang, H., Sharma, M., saif, I. et al. The role of nutrition in harnessing the immune system: a potential approach to prevent cancer. Med Oncol 39, 245 (2022). https://doi.org/10.1007/s12032-022-01850-5

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