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Squamous cell carcinoma of the renal pelvis associated with kidney stones: a case report

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Abstract

A 70-year-old female with a long-standing history of kidney calculi presented with vague abdominal pain. Work-up included a CT and MRI of the kidneys. A mass was demonstrated in the superior pole of the left kidney. The mass was biopsied percutaneously under CT guidance. Pathology revealed a poorly differentiated carcinoma, but was inconclusive for a definitive cell type. The patient subsequently underwent a nephrectomy that revealed squamous cell carcinoma of the renal collecting system. She had an uneventful postoperative recovery. Chronic renal calculi pose a risk for the development of squamous metaplasia that may lead to squamous cell carcinoma. Although this malignancy is rare in the upper urinary tracts, patients with long-standing nephrolithiasis should be monitored. This diagnosis should be included in one’s differential when evaluating a renal mass that is associated with chronic inflammatory conditions.

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References

  1. Bhandari A, Alassi O, Rogers C, MacLennan GT. Squamous cell carcinoma of the renal pelvis. J Urol. 2010;183:2023–4.

    Article  PubMed  Google Scholar 

  2. Cadeddu JA, Jarrett TW. Hypercalcemia associated with squamous cell carcinoma of the renal pelvis. J Urol. 1998;160:1798.

    Article  PubMed  CAS  Google Scholar 

  3. Corcoran AT, Hayn MH, Zynger DL, Ogagan PD, Navid F, Davies BD. Squamous cell carcinoma of the renal pelvis with inferior vena cava and iliac vein tumor thrombus. Can J Urol. 2009;16(6):4958–61.

    PubMed  Google Scholar 

  4. Holmäng S, Lele SM, Johansson SL. Squamous cell carcinoma of the renal pelvis and ureter: incidence, symptoms, treatment and outcome. J Urol. 2007;178:51.

    Article  PubMed  Google Scholar 

  5. Kayaselcuk F, Bal N, Guvel S, Egilmez T, Kilinc F, Tuncer I. Carcinosarcoma and squamous cell carcinoma of the renal pelvis associated with nephrolithiasis: a case report of each tumor type. Pathol Res Pract. 2003;199(7):489–92.

    Article  PubMed  Google Scholar 

  6. Kibel AS, Downs TM, Bubley GJ, DeWolf WC. Squamous cell carcinoma of the renal pelvis with inferior vena caval extension. J Urol. 1996;156(4):1436.

    Article  PubMed  CAS  Google Scholar 

  7. Lee TY, Ko SF, Wan YL, Cheng YF, Yang BY, Huang DL, et al. Renal squamous cell carcinoma: CT findings and clinical significance. Abdom Imaging. 1998;23(2):203–8.

    Article  PubMed  CAS  Google Scholar 

  8. Nair B, Sukumar S, Poolari GK, Appu T. Azathioprine-induced squamous cell carcinoma of the kidney. Scand J Urol Nephrol. 2007;41(2):173–5.

    Article  PubMed  Google Scholar 

  9. O’Daly BJ, O’Brien MF, Dowling CM, Crotty TB, Watson AJ, Moriarty MJ, et al. Squamous cell carcinoma of the renal pelvis after curative retroperitoneal radiotherapy for seminoma. Urology. 2007;70(4):812.

    PubMed  Google Scholar 

  10. Papadopoulos I, Wirth B, Weichert-Jacobsen K, Loch T, Wacker HH. Primary squamous cell carcinoma of the ureter and squamous adenocarcinoma of the renal pelvis: 2 case reports. J Urol. 1996;155(1):288–9.

    Article  PubMed  CAS  Google Scholar 

  11. Schena S, Bogetti D, Setty S, Kadkol S, Bruno A, Testa G, et al. Squamous cell carcinoma in a chronically rejected renal allograft. Am J Trans. 2004;4(7):1208–11.

    Article  Google Scholar 

  12. Sivaramakrishna B, Aron M, Ansari MS, Seth A, Goel R, Mundada OP, et al. Squamous cell carcinoma of the renal pelvis manifesting after percutaneous nephrolithotomy for long standing calculus. Int Urol Nephrol. 2004;36(2):149–51.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Urology, Texas Tech University Health Science Center/Grace Medical Center, 3601 4th Street, STOP 7260, Lubbock, TX, 79430, USA

    J. Paonessa

  2. Department of Urology, Grace Medical Center, 2412 50th Street, Lubbock, TX, 79413, USA

    H. Beck

  3. Department of Pathology, Avero Diagnostics, 410 North Utica Avenue, Lubbock, TX, 79416, USA

    S. Cook

Authors
  1. J. Paonessa
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  2. H. Beck
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  3. S. Cook
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Correspondence to J. Paonessa.

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Paonessa, J., Beck, H. & Cook, S. Squamous cell carcinoma of the renal pelvis associated with kidney stones: a case report. Med Oncol 28 (Suppl 1), 392–394 (2011). https://doi.org/10.1007/s12032-010-9704-z

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  • DOI: https://doi.org/10.1007/s12032-010-9704-z

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