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Squamous cell carcinoma of the renal pelvis associated with kidney stones: a case report

Medical Oncology volume 28, pages 392–394 (2011)Cite this article

Abstract

A 70-year-old female with a long-standing history of kidney calculi presented with vague abdominal pain. Work-up included a CT and MRI of the kidneys. A mass was demonstrated in the superior pole of the left kidney. The mass was biopsied percutaneously under CT guidance. Pathology revealed a poorly differentiated carcinoma, but was inconclusive for a definitive cell type. The patient subsequently underwent a nephrectomy that revealed squamous cell carcinoma of the renal collecting system. She had an uneventful postoperative recovery. Chronic renal calculi pose a risk for the development of squamous metaplasia that may lead to squamous cell carcinoma. Although this malignancy is rare in the upper urinary tracts, patients with long-standing nephrolithiasis should be monitored. This diagnosis should be included in one’s differential when evaluating a renal mass that is associated with chronic inflammatory conditions.

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Authors and Affiliations

  1. Department of Urology, Texas Tech University Health Science Center/Grace Medical Center, 3601 4th Street, STOP 7260, Lubbock, TX, 79430, USA

    J. Paonessa

  2. Department of Urology, Grace Medical Center, 2412 50th Street, Lubbock, TX, 79413, USA

    H. Beck

  3. Department of Pathology, Avero Diagnostics, 410 North Utica Avenue, Lubbock, TX, 79416, USA

    S. Cook

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  1. J. Paonessa
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  2. H. Beck
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  3. S. Cook
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Correspondence to J. Paonessa.

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Paonessa, J., Beck, H. & Cook, S. Squamous cell carcinoma of the renal pelvis associated with kidney stones: a case report. Med Oncol 28 (Suppl 1), 392–394 (2011). https://doi.org/10.1007/s12032-010-9704-z

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  • DOI: https://doi.org/10.1007/s12032-010-9704-z

Keywords

  • Squamous cell carcinoma
  • Kidney
  • Urothelium
  • Neoplasms
  • Kidney calculi
  • Prognosis