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Incidence and Risk Factors of Colorectal Cancer in the Iranian Population: a Systematic Review

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Journal of Gastrointestinal Cancer Aims and scope Submit manuscript

Abstract

Purpose

Colorectal cancer (CRC) is one of the most common cancers in the world. The aim of this study was to investigate its incidence and risk factors in the Iranian population.

Methods

A literature search was conducted in PubMed, Web of Science, Scopus, SID, and Magiran from inception until 2019. Studies that reported the incidence rate and risk factors of colorectal cancer were included in this review.

Results

Twenty-one articles that reported the incidence rate and 13 that reported the risk factors were included. The incidence rate was different according to the population type, gender, age, and study year in different regions. The main risk factors for colorectal cancer were high consumption of red meat and fried food and low intake of fruits and vegetables, diabetes, a positive family history, and obesity.

Conclusion

The incidence of CRC has a marked variation in different parts of Iran, and various risk factors are associated with colorectal cancer. According to incidence rate and various risk factors, precise planning is needed to control colorectal cancer in the future.

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Data Availability

This study is a review study.

Abbreviations

CRC:

Colorectal cancer

ASR:

Age-specific incidence rate

WHO:

World Health Organization

NOS:

Newcastle-Ottawa quality assessment scale

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Author information

Authors and Affiliations

  1. Department of Epidemiology, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Hossein Mozafar Saadati

  2. Tehran West Health Center, Iran University of Medical Sciences, Tehran, Iran

    Batool Okhovat

  3. Department of Community Medicine, School of Medicine, Dezful University of Medical Sciences, Dezful, Iran

    Farzad Khodamoradi

  4. Department of Epidemiology and Biostatistics, Tehran University of Medical Sciences, Tehran, Iran

    Farzad Khodamoradi

  5. Tehran, Iran

    Farzad Khodamoradi

Authors
  1. Hossein Mozafar Saadati
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  2. Batool Okhovat
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  3. Farzad Khodamoradi
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Contributions

Farzad Khodamoradi and Hossein Mozafar Saadati had the idea for the article. Farzad Khodamoradi and Hossein Mozafar Saadati performed the literature search and data analysis. Farzad Khodamoradi and Hossein Mozafar Saadati and Batool Okhovat drafted and/or critically revised the work.

Corresponding author

Correspondence to Farzad Khodamoradi.

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Saadati, H.M., Okhovat, B. & Khodamoradi, F. Incidence and Risk Factors of Colorectal Cancer in the Iranian Population: a Systematic Review. J Gastrointest Canc 52, 414–421 (2021). https://doi.org/10.1007/s12029-020-00574-x

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  • DOI: https://doi.org/10.1007/s12029-020-00574-x

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