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Musculoskeletal Metastasis from Primary Rectal Cancer: Series of Two Cases of a Very Rare Occurrence with a Short Literature Review

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References

  1. Lee WS, Yun SH, Chun HK, Lee WY, Yun HR, Kim J, et al. Pulmonary resection for metastases from colorectal cancer: prognostic factors and survival. Int J Color Dis. 2007;22:699–704.

    Article  Google Scholar 

  2. Van Cutsem E, Nordlinger B, Adam R, Köhne CH, Pozzo C, Poston G, et al. Towards a pan-European consensus on the treatment of patients with colorectal liver metastases. Eur J Cancer. 2006;42(14):2212–21.

    Article  Google Scholar 

  3. Tunio MA, AlAsiri M, Riaz K, AlShakwer W, AlArifi M. Skeletal muscle metastasis secondary to adenocarcinoma of colon: a case report and review of literature. J Gastroint Dig Syst. 2013;S12:002.

    Article  Google Scholar 

  4. Ünsal D, Üner A, Simsek A, Üzüm N, Akmansu M. Metastatic rectal adenocarcinoma to forearm muscle: an unusual site of metastasis. Turk J Cancer. 2005;35:181–5.

    Google Scholar 

  5. Jemal A, Center MM, DeSantis C, Ward EM. Global patterns of cancer incidence and mortality rates and trends. Cancer Epidemiol Biomark Prev. 2010;19:1893–907.

    Article  Google Scholar 

  6. de Gramont A, Bosset JF, Milan C, Rougier P, Bouché O, Etienne PL, et al. Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leucovorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer: a French intergroup study. J Clin Oncol. 1997;15:808–15.

    Article  Google Scholar 

  7. Van Cutsem E, Hoff PM, Harper P, Bukowski RM, Cunningham D, Dufour P, et al. Oral capecitabine vs intravenous 5-fluorouracil and leucovorin: integrated efficacy data and novel analyses from two large, randomised, phase III trials. Br J Cancer. 2004;90:1190–7.

    Article  Google Scholar 

  8. Grothey A, Sargent D, Goldberg RM, Schmoll HJ. Survival of patients with advanced colorectal cancer improves with the availability of fluorouracil-leucovorin, irinotecan, and oxaliplatin in the course of treatment. J Clin Oncol. 2004;22:1209–14.

    Article  CAS  Google Scholar 

  9. Tournigand C, André T, Achille E, Lledo G, Flesh M, Mery-Mignard D, et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol. 2004;22:229–37.

    Article  CAS  Google Scholar 

  10. Hurwitz H, Fehrenbacher L, Novotny W, Cartwright T, Hainsworth J, Heim W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med. 2004;350:2335–42.

    Article  CAS  Google Scholar 

  11. Van Cutsem E, Köhne CH, Láng I, Folprecht G, Nowacki MP, Cascinu S, et al. Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor KRAS and BRAF mutation status. J Clin Oncol. 2011;29:2011–9.

    Article  Google Scholar 

  12. Patel NN, Shah PR, Wilson E, Haray PN. An unexpected supraclavicular swelling. World J Surg Oncol. 2007;5:90.

    Article  Google Scholar 

  13. Hoehn JL, Ousley JL, Avecilla CS. Occult carcinoma of the colon and rectum manifesting as osseous metastasis. Dis Colon Rectum. 1979;22:129–32.

    Article  CAS  Google Scholar 

  14. Ihle PM, McBeath AA. Bone metastasis from colonic carcinoma. A case report. J Bone Joint Surg Am. 1973;55:398–400.

    Article  CAS  Google Scholar 

  15. Tsai MS, Su YH, Ho MC, Liang JT, Chen TP, Lai HS, et al. Clinicopathological features and prognosis in resectable synchronous and metachronous colorectal liver metastasis. Ann Surg Oncol. 2007;14:786–94.

    Article  Google Scholar 

  16. Hellman S, Weichselbaum RR. Oligometastases. J Clin Oncol. 1995;13:8–10.

    Article  CAS  Google Scholar 

  17. Khattak MA, Martin HL, Beeke C, Price T, Carruthers S, Kim S, et al. Survival differences in patients with metastatic colorectal cancer and with single site metastatic disease at initial presentation: results from South Australian clinical registry for advanced colorectal cancer. Clin Colorectal Cancer. 2012;11:247–54.

    Article  Google Scholar 

  18. Nakajima M, Morikawa K, Fabra A, Bucana CD, Fidler IJ. Influence of organ environment on extracellular matrix degradative activity and metastasis of human colon carcinoma cells. J Natl Cancer Inst. 1990;82:1890–8.

    Article  CAS  Google Scholar 

  19. Fidler IJ, Wilmanns C, Staroselsky A, Radinsky R, Dong Z, Fan D. Modulation of tumor cell response to chemotherapy by the organ environment. Cancer Metastasis Rev. 1994;13:209–22.

    Article  CAS  Google Scholar 

  20. Dalton WS. The tumor microenvironment as a determinant of drug response and resistance. Drug Resist Updat. 1999;2:285–8.

    Article  CAS  Google Scholar 

  21. Tarin D. Clinical and biological implications of the tumor microenvironment. Cancer Microenviron. 2012;5:95–112.

    Article  CAS  Google Scholar 

  22. Takada J, Watanabe K, Kuraya D, Kina M, Hayashi S, Hamada H, et al. An example of metastasis to the iliopsoas muscle from sigmoid colon cancer. Gan To Kagaku Ryoho. 2011;38(12):2294–7.

    PubMed  Google Scholar 

  23. Naik VR, Jaafar H, Mutum SS. Heterotopic ossification in skeletal muscle metastasis from colonic adenocarcinoma - a case report. Malays J Pathol. 2005;27:119–21.

    PubMed  Google Scholar 

  24. Burgueño Montañés C, López Roger R. Exophthalmos secondary to a lateral rectus muscle metastasis. Arch Soc Esp Oftalmol. 2002;77:507–10.

    PubMed  Google Scholar 

  25. Hasegawa S, Sakurai Y, Imazu H, Matsubara T, Ochiai M, Funabiki T, et al. Metastasis to the forearm skeletal muscle from an adenocarcinoma of the colon: report of a case. Surg Today. 2000;30:1118–23.

    Article  CAS  Google Scholar 

  26. Homan HH, Mühlberger T, Kuhnen C, Steinau HU. Intramuscular extremity metastasis of adenocarcinoma of the colon. Chirurg. 2000;71:1392–4.

    Article  CAS  Google Scholar 

  27. Bonjer HJ, Lange JF, Jansen A, Schouten WR, Jakimowicz J, Cuesta Valentin MA, et al. Abdominal wall metastasis following surgical removal of colorectal carcinomas. Ned Tijdschr Geneeskd. 1997;141:1868–70.

    CAS  PubMed  Google Scholar 

  28. Jacquet P, Averbach AM, Jacquet N. Abdominal wall metastasis and peritoneal carcinomatosis after laparoscopic-assisted colectomy for colon cancer. Eur J Surg Oncol. 1995;21:568–70.

    Article  CAS  Google Scholar 

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Acknowledgements

We would like to acknowledge the Departments of Pathology, Radiology, and Nuclear Medicine at Command Hospital (SC), Pune, for their support.

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  1. Malignant Disease Treatment Centre, Command Hospital (SC), Pune, 411040, India

    Sankalp Singh, Niharika Bisht, Richa Joshi, Prabha Shankar Mishra, Deepak Mulajker & Samir Gupta

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  1. Sankalp Singh
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  2. Niharika Bisht
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  3. Richa Joshi
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Correspondence to Sankalp Singh.

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Singh, S., Bisht, N., Joshi, R. et al. Musculoskeletal Metastasis from Primary Rectal Cancer: Series of Two Cases of a Very Rare Occurrence with a Short Literature Review. J Gastrointest Canc 50, 991–996 (2019). https://doi.org/10.1007/s12029-018-0165-5

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  • DOI: https://doi.org/10.1007/s12029-018-0165-5

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