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IgG4-Associated Adrenalitis—a Case Report

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Abstract

A 67-year-old man was adrenalectomized due to a tumor measuring 100 mm. Specimens revealed an inflammation with slight fibrosis and moderate infiltrates of lymphocytes and plasmacytes with immunoreactivity for IgG and IgG4 resulting in the diagnosis of an active IgG4-associated adrenalitis. To our knowledge, this is the first reported active adrenalitis of this type. It should be the precursor lesion of the adrenal calcifying fibrous tumor that was reported once before.

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Authors and Affiliations

  1. Institute of Pathology of the University of Hamburg, Martinistraße 52, UKE, 20246, Hamburg, Germany

    Wolfgang Saeger

  2. Institute of Pathology, Städtisches Klinikum Karlsruhe, 76042, Karlsruhe, Germany

    Bernd Lohe & Christina Luise Engels

  3. Clinic of Urology, Städtisches Klinikum Karlsruhe, 76042, Karlsruhe, Germany

    Ulrike Werner

Authors
  1. Wolfgang Saeger
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  2. Bernd Lohe
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  3. Christina Luise Engels
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  4. Ulrike Werner
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Contributions

W. Saeger: histopathology, immunocytochemistry, conception

B. Lohe, Ch. L. Engels: histopathology

U. Werner: clinics, surgery.

Corresponding author

Correspondence to Wolfgang Saeger.

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This article does not contain any studies with human participants performed by any of the authors.

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The authors declare that they have no conflict of interests.

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Saeger, W., Lohe, B., Engels, C.L. et al. IgG4-Associated Adrenalitis—a Case Report. Endocr Pathol 29, 294–298 (2018). https://doi.org/10.1007/s12022-018-9531-x

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  • DOI: https://doi.org/10.1007/s12022-018-9531-x

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