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Ectopic Prolactin-Producing Pituitary Adenoma in a Benign Ovarian Cystic Teratoma

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Abstract

We report the presence of pituitary tissue in a benign ovarian cystic teratoma removed surgically from a 43-year-old woman. The pituitary consisted of non-tumorous neurohypophysis and adenohypophysis containing mainly prolactin (PRL)-immunopositive cells (80 % of cells) and a small PRL-producing adenoma. The ultrastructure of the tumor cells differed significantly from PRL cells in the non-tumorous and adenomatous intrasellar pituitary. It appears that cells differing in ultrastructure from intrasellar pituitary PRL cells can also produce PRL.

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Acknowledgments

Authors are grateful to the Jarislowsky and Lloyd Carr-Harris Foundations for their generous support.

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Authors and Affiliations

  1. Department of Laboratory Medicine, Division of Pathology, St. Michael’s Hospital, 30 Bond Street, Toronto, ON, Canada, M5B 1W8

    Saba Al-Bazzaz, Jason Karamchandani, Eva Horvath, Fabio Rotondo & Kalman Kovacs

  2. Department of Obstetrics and Gynecology, St. Michael’s Hospital, Toronto, ON, Canada

    Eva Mocarski

Authors
  1. Saba Al-Bazzaz
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  2. Jason Karamchandani
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  3. Eva Mocarski
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  4. Eva Horvath
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  5. Fabio Rotondo
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  6. Kalman Kovacs
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Correspondence to Saba Al-Bazzaz.

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Al-Bazzaz, S., Karamchandani, J., Mocarski, E. et al. Ectopic Prolactin-Producing Pituitary Adenoma in a Benign Ovarian Cystic Teratoma. Endocr Pathol 25, 321–323 (2014). https://doi.org/10.1007/s12022-014-9299-6

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  • DOI: https://doi.org/10.1007/s12022-014-9299-6

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