Abstract
Liu et al. have carried out a meta-analysis of case–control studies to investigate the association between PICALM gene rs3851179 polymorphism and Alzheimer’s disease in an Asian population. However, several important issues should be noted.
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References
Dickersin, K., Scherer, R., & Lefebvre, C. (1994). Identifying relevant studies for systematic reviews. BMJ, 309(6964), 1286–1291.
Higgins, J. P., & Thompson, S. G. (2002). Quantifying heterogeneity in a meta-analysis. Statistics in Medicine, 21(11), 1539–1558. doi:10.1002/sim.1186.
Lemeshow, A. R., Blum, R. E., Berlin, J. A., Stoto, M. A., & Colditz, G. A. (2005). Searching one or two databases was insufficient for meta-analysis of observational studies. Journal of Clinical Epidemiology, 58(9), 867–873. doi:10.1016/j.jclinepi.2005.03.004.
Liu, G., Zhang, S., Cai, Z., Ma, G., Zhang, L., Jiang, Y., et al. (2013). PICALM gene rs3851179 polymorphism contributes to Alzheimer’s disease in an Asian population. NeuroMolecular Medicine, 15(2), 384–388. doi:10.1007/s12017-013-8225-2.
Ziegler, A., Van Steen, K., & Wellek, S. (2011). Investigating Hardy–Weinberg equilibrium in case–control or cohort studies or meta-analysis. Breast Cancer Research and Treatment, 128(1), 197–201. doi:10.1007/s10549-010-1295-z.
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Wang, MJ., Liu, RP. & Kong, ZJ. Re: “PICALM Gene rs3851179 Polymorphism Contributes to Alzheimer’s Disease in an Asian Population”. Neuromol Med 18, 155–156 (2016). https://doi.org/10.1007/s12017-016-8387-9
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DOI: https://doi.org/10.1007/s12017-016-8387-9