Skip to main content

Advertisement

SpringerLink
Log in

Infections Related to Totally Implantable Venous-Access Ports: Long-Term Experience in One Center

  • Original Paper
  • Published:
Cell Biochemistry and Biophysics Aims and scope Submit manuscript

Abstract

The purpose of this study was to investigate the incidence and risk factors of infections associated with totally implantable venous-access ports (TIVAPs) in our hospital. From April 2007 through November 2013, a total of 1,026 patients with TIVAP were included in this study. We retrospectively analyzed the incidence of port-related infection, patient characteristics, and history. Risk factors for IVAP-related infection were determined statistically. Overall, 97 (9.59 %) of 1,026 infectious cases were reported. By reviewing the medical record of the patients, we found that younger age, hematogenous malignancy, and palliative chemotherapy were associated with higher infection incidence rate in patients who had implanted TIVAP (P < 0.05) in the subgroup analysis. In contrast, gender and insertion site were irrelevant factors in predicting the infection risk. Overall, TIVAP were proved to be safe and effective. Younger age, hematogenous malignancy, and palliative chemotherapy were associated with higher infection in patients who had implanted TIVAP.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Pittiruti, M., Hamilton, H., Biffi, R., MacFie, J., & Pertkiewicz, M. (2009). Espen, ESPEN guidelines on parenteral nutrition: Central venous catheters (access, care, diagnosis and therapy of complications). Clinical Nutrition, 28, 365–377.

    Article  PubMed  Google Scholar 

  2. Niederhuber, J. E., Ensminger, W., Gyves, J. W., Liepman, M., Doan, K., & Cozzi, E. (1982). Totally implanted venous and arterial access system to replace external catheters in cancer treatment. Surgery, 92, 706–712.

    CAS  PubMed  Google Scholar 

  3. Vescia, S., Baumgartner, A. K., Jacobs, V. R., Kiechle-Bahat, M., Rody, A., Loibl, S., & Harbeck, N. (2008). Management of venous port systems in oncology: A review of current evidence. Annals of Oncology: Official Journal of The European Society for Medical Oncology/ESMO, 19, 9–15.

    Article  CAS  Google Scholar 

  4. Nocito, A., Wildi, S., Rufibach, K., Clavien, P. A., & Weber, M. (2009). Randomized clinical trial comparing venous cutdown with the Seldinger technique for placement of implantable venous access ports. The British Journal of Surgery, 96, 1129–1134.

    Article  CAS  PubMed  Google Scholar 

  5. Barbetakis, N., Asteriou, C., Kleontas, A., & Tsilikas, C. (2011). Totally implantable central venous access ports. Analysis of 700 cases. Journal of Surgical Oncology, 104, 654–656.

    Article  PubMed  Google Scholar 

  6. Kurul, S., Saip, P., & Aydin, T. (2002). Totally implantable venous-access ports: local problems and extravasation injury. The lancet Oncology, 3, 684–692.

    Article  PubMed  Google Scholar 

  7. Schwarz, R. E., Groeger, J. S., & Coit, D. G. (1997). Subcutaneously implanted central venous access devices in cancer patients: A prospective analysis. Cancer, 79, 1635–1640.

    Article  CAS  PubMed  Google Scholar 

  8. Kock, H. J., Pietsch, M., Krause, U., Wilke, H., & Eigler, F. W. (1998). Implantable vascular access systems: experience in 1500 patients with totally implanted central venous port systems. World Journal of Surgery, 22, 12–16.

    Article  CAS  PubMed  Google Scholar 

  9. Chang, L., Tsai, J. S., Huang, S. J., & Shih, C. C. (2003). Evaluation of infectious complications of the implantable venous access system in a general oncologic population. American Journal of Infection Control, 31, 34–39.

    Article  PubMed  Google Scholar 

  10. Hsieh, C. C., Weng, H. H., Huang, W. S., Wang, W. K., Kao, C. L., Lu, M. S., & Wang, C. S. (2009). Analysis of risk factors for central venous port failure in cancer patients. World Journal of Gastroenterology: WJG, 15, 4709–4714.

    Article  PubMed Central  PubMed  Google Scholar 

  11. Fischer, L., Knebel, P., Schroder, S., Bruckner, T., Diener, M. K., Hennes, R., et al. (2008). Reasons for explantation of totally implantable access ports: a multivariate analysis of 385 consecutive patients. Annals of Surgical Oncology, 15, 1124–1129.

    Article  PubMed  Google Scholar 

  12. Groeger, J. S., Lucas, A. B., Thaler, H. T., Friedlander-Klar, H., Brown, A. E., Kiehn, T. E., & Armstrong, D. (1993). Infectious morbidity associated with long-term use of venous access devices in patients with cancer. Annals of Internal Medicine, 119, 1168–1174.

    Article  CAS  PubMed  Google Scholar 

  13. Bassi, K. K., Giri, A. K., Pattanayak, M., Abraham, S. W., & Pandey, K. K. (2012). Totally implantable venous access ports: retrospective review of long-term complications in 81 patients. Indian Journal of Cancer, 49, 114–118.

    Article  CAS  PubMed  Google Scholar 

  14. Mermel, L.A., Farr, B.M., Sherertz, R.J., Raad, I.I., O’Grady, N., Harris, J.S., Craven, D.E. (2001). A. Infectious Diseases Society of, M. American College of Critical Care, A. Society for Healthcare Epidemiology of, Guidelines for the management of intravascular catheter-related infections. Clinical Infectious Diseases: An Official Publication of The Infectious Diseases Society of America 32, 1249–1272.

  15. Mermel, L. A., Allon, M., Bouza, E., Craven, D. E., Flynn, P., O’Grady, N. P., et al. (2009). Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of America. Clinical Infectious Diseases: An Official Publication of The Infectious Diseases Society of America, 49, 1–45.

    Article  CAS  Google Scholar 

  16. Shim, J., Seo, T. S., Song, M. G., Cha, I. H., Kim, J. S., Choi, C. W., et al. (2014). Incidence and risk factors of infectious complications related to implantable venous-access ports. Korean Journal of Radiology: Official Journal of the Korean Radiological Society, 15, 494–500.

    Article  Google Scholar 

  17. Hickman, R. O., Buckner, C. D., Clift, R. A., Sanders, J. E., Stewart, P., & Thomas, E. D. (1979). A modified right atrial catheter for access to the venous system in marrow transplant recipients. Surgery, Gynecology & Obstetrics, 148, 871–875.

    CAS  Google Scholar 

  18. Broviac, J. W., Cole, J. J., & Scribner, B. H. (1973). A silicone rubber atrial catheter for prolonged parenteral alimentation. Surgery, Gynecology & Obstetrics, 136, 602–606.

    CAS  Google Scholar 

  19. Reed, W. P., Newman, K. A., de Jongh, C., Wade, J. C., Schimpff, S. C., Wiernik, P. H., & McLaughlin, J. S. (1983). Prolonged venous access for chemotherapy by means of the Hickman catheter. Cancer, 52, 185–192.

    Article  CAS  PubMed  Google Scholar 

  20. Carde, P., Cosset-Delaigue, M. F., Laplanche, A., & Chareau, I. (1989). Classical external indwelling central venous catheter versus totally implanted venous access systems for chemotherapy administration: A randomized trial in 100 patients with solid tumors. European Journal of Cancer & Clinical Oncology, 25, 939–944.

    Article  CAS  Google Scholar 

  21. Stanislav, G. V., Fitzgibbons, R. J, Jr, Bailey, R. T, Jr, Mailliard, J. A., Johnson, P. S., & Feole, J. B. (1987). Reliability of implantable central venous access devices in patients with cancer. Archives of Surgery, 122, 1280–1283.

    Article  CAS  PubMed  Google Scholar 

  22. Biffi, R., Corrado, F., de Braud, F., de Lucia, F., Scarpa, D., Testori, A., et al. (1997). Long-term, totally implantable central venous access ports connected to a Groshong catheter for chemotherapy of solid tumours: experience from 178 cases using a single type of device. European Journal of Cancer, 33, 1190–1194.

    Article  CAS  PubMed  Google Scholar 

  23. Silberzweig, J. E., Sacks, D., Khorsandi, A. S., & Bakal, C. W. (2000). Reporting standards for central venous access. Technology Assessment Committee. Journal of Vascular and Interventional Radiology: JVIR, 11, 391–400.

    Article  CAS  PubMed  Google Scholar 

  24. Gebauer, B., El-Sheik, M., Vogt, M., & Wagner, H. J. (2009). Combined ultrasound and fluoroscopy guided port catheter implantation–high success and low complication rate. European Journal of Radiology, 69, 517–522.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. The Jiangyin Affiliated Hospital of Medical College of Southeast University, Jiangyin, China

    Lijun Ji, Jinghua Yang, Jianzhong Miao, Qing Shao, Yuerong Cao & Hao Li

Authors
  1. Lijun Ji
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jinghua Yang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Jianzhong Miao
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Qing Shao
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Yuerong Cao
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Hao Li
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Yuerong Cao or Hao Li.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ji, L., Yang, J., Miao, J. et al. Infections Related to Totally Implantable Venous-Access Ports: Long-Term Experience in One Center. Cell Biochem Biophys 72, 235–240 (2015). https://doi.org/10.1007/s12013-014-0443-1

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12013-014-0443-1

Keywords

Search

Navigation