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Long-Term Treatment After Preoperative High-Dose Chemotherapy in a Lactating Breast Cancer Patient

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Abstract

Breast cancer during lactation is very rare, accounting for <3 % of all breast cancers. Its diagnosis and treatment is often delayed during pregnancy. We report a case of female lactating breast carcinoma in a 29-year old patient. The disease was stage IIIB (T4N1M0). The patient received preoperative induction chemotherapy and high-dose chemotherapy with peripheral blood stem cell support, followed by adjuvant chemotherapy and endocrine therapy. The metastases were detected 17 months after operation, palliative treatment including different chemotherapy for 60 cycles, locoregional radiotherapy and endocrine therapy. The total number of cycles of chemotherapy was 67, and the survival time was 118 months. We discuss the diagnosis and treatment options for breast cancer during lactation, based on a literature review.

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Authors and Affiliations

  1. Department of Radiotherapy, The Affiliated Jiangsu Cancer Hospital, Nanjing Medical University, Nanjing, 210009, China

    Chengyun Yao

  2. Division of Cellular and Molecular Research, National Cancer Center Singapore, Singapore, 169610, Singapore

    Hongping Xia

  3. Department of Respiratory Medicine, Drum Tower Hospital, Nanjing University Medical School, Nanjing, 210008, China

    Yongsheng Wang

  4. Department of General Surgery, The Affiliated Jiangsu Cancer Hospital, Nanjing Medical University, Nanjing, 210009, China

    Jinhai Tang

  5. Department of Chemotherapy, The Affiliated Jiangsu Cancer Hospital, Nanjing Medical University, Nanjing, 210009, China

    Xiaobo Wang

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  1. Chengyun Yao
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  2. Hongping Xia
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  3. Yongsheng Wang
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  4. Jinhai Tang
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  5. Xiaobo Wang
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Corresponding author

Correspondence to Jinhai Tang.

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Chengyun Yao and Hongping Xia have contributed equally to this work.

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Yao, C., Xia, H., Wang, Y. et al. Long-Term Treatment After Preoperative High-Dose Chemotherapy in a Lactating Breast Cancer Patient. Cell Biochem Biophys 69, 61–64 (2014). https://doi.org/10.1007/s12013-013-9766-6

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  • DOI: https://doi.org/10.1007/s12013-013-9766-6

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