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Selenium Mitigates Cadmium-Induced Adverse Effects on Trace Elements and Amino Acids Profiles in Chicken Pectoral Muscles

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Abstract

Cadmium (Cd), as one of the most toxic heavy metals, has become a widespread environmental contaminant and threats the food quality and safety. The protective effect of selenium (Se) on Cd-induced tissue lesion and cytotoxicity in chicken has been extensively reported. The objective of this study was to investigate the antagonistic effect of Se on Cd-induced damage of chicken pectoral muscles via analyzing the trace elements and amino acids profiles. Firstly, 19 trace elements contents were analyzed by inductively coupled plasma mass spectrometry (ICP-MS). The results showed that under Cd exposure, the contents of Cd, lead (Pb), mercury (Hg), aluminum (Al), and lithium (Li) were significantly elevated, and the contents of Se, iron (Fe), and chromium (Cr) were significantly reduced. However, supplementing Se significantly reversed the effects induced by Cd. Secondly, the amino acids contents were detected by L-8900 automatic amino acid analyzer. The results showed that supplementing Se increased significantly Cd-induced decrease of valine (Val), leucine (Leu), arginine (Arg), and proline (Pro). Thirdly, the results of principal component analysis (PCA) showed that cobalt (Co), manganese (Mn), silicium (Si), and Pro may play special roles in response to the process of Se antagonizes Cd-induced damage of pectoral muscles in chickens. In summary, these results indicated that different trace elements and amino acids possessed and exhibited distinct responses to suffer from Se and/or Cd in chicken pectoral muscles. Notably, Se alleviated Cd-induced adverse effects by regulating trace elements and amino acids profiles in chicken pectoral muscles.

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Abbreviations

Se:

Selenium

Fe:

Iron

Zn:

Zinc

Cu:

Copper

Cr:

Chromium

Co:

Cobalt

Mn:

Manganese

Mo:

Molybdenum

Si:

Silicium

Ni:

Nickel

B:

Boron

V:

Vanadium

Cd:

Cadmium

Pb:

Lead

Hg:

Mercury

As:

Arsenic

Al:

Aluminum

Sn:

Tin

Li:

Lithium

Sb:

Stibium

Tl:

Thallium

ICP-MS:

Inductively coupled plasma mass spectrometry

Thr:

Threonine

Val:

Valine

Met:

Methionine

Ile:

Isoleucine

Leu:

Leucine

Phe:

Phenylalanine

Lys:

Lysine

Asp:

Aspartic acid

Ser:

Serine

Glu:

Glutamic acid

Gly:

Glycine

Ala:

Alanine

Cys:

Cysteine

Tyr:

Tyrosine

His:

Histidine

Arg:

Arginine

Pro:

Proline

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Funding

This work was supported by the Doctoral Foundation of Shandong Province (ZR2018BC048) and Funds of Shandong “Double Tops” Program.

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Author notes

  1. Kui-Chao Qu and Hui-Qin Li contributed equally to this work.

Authors and Affiliations

  1. College of Animal Science and Veterinary Medicine, Shandong Agricultural University, 61 Daizong Street, Tai’an City, 271018, Shandong Province, China

    Kui-Chao Qu, Kou-Kou Tang, Zhen-Yong Wang & Rui-Feng Fan

  2. Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, 61 Daizong Street, Tai’an City, 271018, Shandong Province, China

    Kui-Chao Qu, Kou-Kou Tang, Zhen-Yong Wang & Rui-Feng Fan

  3. Shandong Provincial Engineering Technology Research Center of Animal Disease Control and Prevention, Shandong Agricultural University, 61 Daizong Street, Tai’an City, 271018, Shandong Province, China

    Kui-Chao Qu, Kou-Kou Tang, Zhen-Yong Wang & Rui-Feng Fan

  4. College of Veterinary Medicine, Northeast Agricultural University, Harbin, 150030, People’s Republic of China

    Hui-Qin Li

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  1. Kui-Chao Qu
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Correspondence to Rui-Feng Fan.

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Qu, KC., Li, HQ., Tang, KK. et al. Selenium Mitigates Cadmium-Induced Adverse Effects on Trace Elements and Amino Acids Profiles in Chicken Pectoral Muscles. Biol Trace Elem Res 193, 234–240 (2020). https://doi.org/10.1007/s12011-019-01682-x

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