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Selenium–Chromium(VI) Interaction Regulates the Contents and Correlations of Trace Elements in Chicken Brain and Serum

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Abstract

This study aims to investigate the contents of trace elements in the brain and serum of male chickens and the effect of selenium–chromium(VI) interaction. A chronic experimental model was established by supplementing 22.14 mg/kg K2Cr2O7 with 0.00, 0.31, 0.63, 1.25, 2.50, and 5.00 mg/kg Na2SeO3 mg/kg B.W. to water for chicken daily. After 14, 28, and 42 days of exposure to the solution, the brain and serum of chickens from each group were collected to detect the levels of Ca, Cu, Mn, Fe, Zn, and Mg by inductively coupled plasma mass spectrometer (ICP-MS). Cr(VI) time-dependently accumulated in the brain and serum. The contents of Cr increased both in the brain and serum with prolonged exposure. Cr contents in the brain and serum decreased in all Se groups compared with those in only Cr-treated groups. Ca contents decreased with prolonged exposure and increasing Se dosage. The contents of Cu and Mn increased on the 28th day but decreased on the 42nd day in the brain and serum. Fe and Zn contents decreased in the serum under prolonged exposure and increased on the 28th day but decreased on the 42nd day in the brain. Cr exposure did not significantly affect Mg contents in the brain but slightly decreased those in the serum. Therefore, appropriate doses of Se affected Cr accumulation, leading to adjustments in the contents and correlations of trace elements.

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Acknowledgements

This work was supported by the National Key R&D Program (2016YFD0501208, 2016YFD0501007) and the Shandong Modern Agricultural Technology & Industry System (No. SDAIT-11-04).

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Authors and Affiliations

  1. College of Veterinary Medicine, Research Center for Animal Disease Control Engineering, Shandong Province, Shandong Agricultural University, Tai’an, 271018, China

    Yiran Zhu, Peng Chen, Huiyu Wan, Yang Wang, Pan Hao & Jianzhu Liu

  2. Research Center for Animal Disease Control Engineering, Shandong Agricultural University, Tai’an, Shandong, 271018, China

    Yongxia Liu

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  1. Yiran Zhu
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  2. Peng Chen
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  4. Yang Wang
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  7. Jianzhu Liu
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Correspondence to Yongxia Liu or Jianzhu Liu.

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The animal care and use procedures applied in the study were conducted under the protocols approved by the Institutional Animal Care and Use Committee of Shandong Agricultural University (SDAU 2015-07).

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The authors declare that they have no competing interests.

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Zhu, Y., Chen, P., Wan, H. et al. Selenium–Chromium(VI) Interaction Regulates the Contents and Correlations of Trace Elements in Chicken Brain and Serum. Biol Trace Elem Res 181, 154–163 (2018). https://doi.org/10.1007/s12011-017-1038-7

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  • DOI: https://doi.org/10.1007/s12011-017-1038-7

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