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Trace Elements Analysis of Urine and Hair in Tuberculous Pleurisy

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Abstract

In this study, copper, zinc, magnesium, manganese, selenium, and iron of urine and hair were measured in the patients with tuberculous (TB) pleurisy (n = 24) and in the control group (n = 20). Selenium, magnesium, and zinc of hair were found to be significantly lower in TB pleurisy cases than those in the control group (p < 0.05, p < 0.001, and p < 0.01, respectively). On the contrary, selenium and magnesium of urine were found to be significantly elevated in TB pleurisy cases than those in the control group (p < 0.05 and p < 0.001, respectively). There was no significant difference in the value of manganese and iron between TB pleurisy and the control group (p > 0.05). Copper level were significantly increased in hair and decreased in urine of the patients (p < 0.01). The occurrence of these abnormalities constitutes new information regarding trace elements in TB pleurisy patients. These results may provide an additional disease correlate for assessing TB pleurisy risk.

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References

  1. Parr RM, Taylor DM (1964) The concentrations of cobalt, copper, iron and zinc in some normal human tissues as determined by neutron-activation analysis. Biochem J 91:424

    PubMed  CAS  Google Scholar 

  2. Clayman CB (1989) American Medical Association. Am Med Assoc Encycl Med 396:605–752

    Google Scholar 

  3. Muralidhar LH (2004) Serum trace element levels and the complexity of inter element relations in patients with Parkinson's disease. J Trace Elem Med Biol 18:163–171

    Article  Google Scholar 

  4. Sakuraba M, Masuda K, Hebisawa A, Sagara Y, Komatsu H (2009) Pleural effusion adenosine deaminase (ADA) level and occult tuberculous pleurisy. Ann Thorac Cardiovasc Surg 15(5):294–296

    PubMed  Google Scholar 

  5. Gopi A, Madhavan SM, Sharma SK, Sahn SA (2007) Diagnosis and treatment of tuberculous pleural effusion in 2006. Chest 1:880–889

    Article  Google Scholar 

  6. Trajman A, Pai M, Dheda K, van Zyl SR, Zwerling AA et al (2008) Novel tests for diagnosing tuberculous pleural effusion: what works and what does not? Eur Respir J 31:1098–1106

    Article  PubMed  CAS  Google Scholar 

  7. Pai M, Flores LL, Hubbard A, Riley LW, Colford JM Jr (2004) Nucleic acid amplification tests in the diagnosis of tuberculous pleuritis: a systematic review and meta-analysis. BMC Infect Dis 4:6

    Article  PubMed  Google Scholar 

  8. Chen ML, Yu WC, Lam CW, Au KM, Kong FY et al (2004) Diagnostic value of pleural fluid adenosine deaminase activity in tuberculous pleurisy. Clin Chim Acta 341:101–107

    Article  PubMed  CAS  Google Scholar 

  9. Titarenko OT, D’iakova ME, Perova TL, D’iakova AI, Popov MIu (2002) Informative value of adenosine deaminase and 2-deoxyadenosine deaminase in the diagnosis of tuberculous pleurisy. Klin Lab Diagn 5:11–14 (in Russian)

    PubMed  Google Scholar 

  10. Sharma SK, Suresh V, Mohan A, Kaur P, Saha P et al (2001) A prospective study of sensitivity and specificity of adenosine deaminase estimation in the diagnosis of tuberculosis pleural effusion. Indian J Chest Dis Allied Sci 43:149–155

    PubMed  CAS  Google Scholar 

  11. Bueso FJ, Hernando VH, Garcia-Buela JP, Juncal DL, Egana MMT et al (1988) Diagnostic value of simultaneous determination of pleural adenosine deaminase and pleural lysozyme/serum lysozyme ratio in pleural effusions. Chest 93:303–307

    Article  Google Scholar 

  12. Ocana I, Martinez-Vazquez JM, Segura RM, Fernandez-De-Sevilla T, Capdevila JA (1983) Adenosine deaminase in pleural fluids. Test for diagnosis of tuberculous pleural effusion. Chest 84:51–53

    Article  PubMed  CAS  Google Scholar 

  13. Wang GQ, Lin MY (2010) Serum trace element levels in tuberculous pleurisy. Biol Trace Elem Res (in press)

  14. Han C, Li J, Hui Q (2008) Determination of trace elements in Jinqi, a traditional Chinese medicine. Biol Trace Elem Res 122(2):122–126

    Article  PubMed  CAS  Google Scholar 

  15. Vallee B, Coleman J, Auld D (1991) Zinc fingers, zinc clusters, and zinc twists in DNA-binding protein domains. Proc Natl Acad Sci USA 88:999–1003

    Article  PubMed  CAS  Google Scholar 

  16. Vallee B, Falchuk K (1993) The biochemical basis of zinc physiology. Physiol Rev 73:79–118

    Article  PubMed  CAS  Google Scholar 

  17. Blanchard R, Cousins R (1996) Differential display of intestinal mRNAs regulated by dietary zinc. Proc Natl Acad Sci USA 93:6863–6868

    Article  PubMed  CAS  Google Scholar 

  18. Chesters J, Petrie L, Travis A (1990) A requirement for Zn2+ for the induction of thymidine kinase but not ornithine decarboxylase in 3T3 cells stimulated from quiescence. Biochem J 272:525–527

    PubMed  CAS  Google Scholar 

  19. Pekarek RS, Wannemacher RW Jr, Beisel WR (1972) Effect of leukocytic endogenous mediator (LEM) on the tissue distribution of zinc and iron. Proc Soc Exp Biol Med 140:685–688

    PubMed  CAS  Google Scholar 

  20. Beyenbach KW (1990) Transport of magnesium across biological membranes. Magnes Trace Elem 9:233–254

    PubMed  CAS  Google Scholar 

  21. Williams RJP (1970) The biochemistry of sodium, potassium, magnesium and calcium. Q Rev Chem Soc 24:331–365

    Article  CAS  Google Scholar 

  22. Schrauzer GN, Rhead WJ, Evans GA (1973) Selenium and cancer. Chemical interpretation of a plasma cancer test. Bioinorgan Chem 2:329–340

    Article  CAS  Google Scholar 

  23. Shamberger RJ, Rukovena E, Longfield AK, Tytko SA, Deodher S, Willis CE (1973) Antioxidants and cancer. I. Selenium in the blood of normals and cancer patients. J Natl Cancer Inst 50:863–870

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Respiratory, Qilu Hospital of Shandong University, Jinan, 250012, People’s Republic of China

    Bao-Yi Liu

  2. Department of Respiratory, Shandong Chest Hospital, Jinan, 250013, People’s Republic of China

    Xue-Mei Bu

  3. Department of Respiratory, The Affiliated Hospital of Medical College Qingdao University, Qingdao, 266003, People’s Republic of China

    Guang-Qiang Wang

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  1. Bao-Yi Liu
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  2. Xue-Mei Bu
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Correspondence to Guang-Qiang Wang.

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Liu, BY., Bu, XM. & Wang, GQ. Trace Elements Analysis of Urine and Hair in Tuberculous Pleurisy. Biol Trace Elem Res 143, 1319–1324 (2011). https://doi.org/10.1007/s12011-011-8975-3

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  • DOI: https://doi.org/10.1007/s12011-011-8975-3

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