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Comparison of Vanadium-Rich Activity of Three Species Fungi of Basidiomycetes

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Abstract

A comparison of vanadium-rich activity of three species fungi of Basidiomycetes, Ganoderma lucidum, Coprinus comatus, and Grifola frondosa, was studied. By fermentation and atomic absorption spectroscopy analysis, the biomass of G. lucidum and G. frondosa declined rapidly when the concentration of vanadium exceeded 0.3% but the biomass of C. comatus did not decline rapidly until the concentration of vanadium exceeded 0.4% and the content of vanadium accumulated in the mycelia was 3529.3 μg/g. After the mice were administered (intragastrically) with vanadium-rich C. comatus, the blood glucose of alloxan-induced hyperglycemic mice was decreased (p < 0.05) and the body weight of the alloxan-induced hyperglycemic mice was increased gradually. Thus, we selected C. comatus to absorb vanadium and chose 0.4% as the optimal concentration of vanadium for the pharmacological works.

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Acknowledgment

This project is supported by Natural Science Fund of Shandong (Y2006B23).

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Authors and Affiliations

  1. School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, People’s Republic of China

    Chunchao Han

  2. College of Food and Bioengineering, Shandong Institute of Light Industry, Jinan, 250353, People’s Republic of China

    Bo Cui & Jingran Qu

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  1. Chunchao Han
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  2. Bo Cui
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  3. Jingran Qu
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Correspondence to Chunchao Han.

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Han, C., Cui, B. & Qu, J. Comparison of Vanadium-Rich Activity of Three Species Fungi of Basidiomycetes. Biol Trace Elem Res 127, 278–283 (2009). https://doi.org/10.1007/s12011-008-8246-0

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  • DOI: https://doi.org/10.1007/s12011-008-8246-0

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