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A Comparative Analysis of Heavy Metal Effects on Medicinal Plants

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Abstract

Popularity of herbal drugs has always been in high demand, but recently it has been increasing all over the world, especially in India, because of the lower range of adverse health effects as compared to synthetic or man-made drugs. Not only this but their cost-effectiveness and easy availability to the poor people and the masses, particularly in developing countries, are major causes for their demand. But there lies a huge problem during the process of plant collection that affects their medicinal properties to certain degrees. This is caused by heavy metal toxicity in soil in different locations of the Indian subcontinent. This was correlated with their potential to cause health damage. Exposure of humans to heavy metals includes diverse pathways from food to water to consumption and inhalation of polluted air to permanent damage to exposed skin and even by occupational exposure at workplaces. As we can understand, the main mechanisms of heavy metal toxicity include the production of free radicals to affect the host by oxidative stress, damaging biological molecules such as enzymes, proteins, lipids, and even nucleic acids and finally damaging DNA which is the fastest way to carcinogenesis and in addition, neurotoxicity. Therefore, in this paper, we have researched how the plants/herbs are affected due to heavy metal deposition in their habitat and how it can lead to serious clinical complications.

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Acknowledgements

The authors gratefully acknowledge the University of Engineering and Management, Kolkata, and all the members of the Department of Biotechnology for their kind cooperation in completion of this work.

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  1. Department of Biotechnology, University of Engineering and Management, Kolkata, India

    Susmita Mukherjee, Nivedita Chatterjee, Asmeeta Sircar, Shimantika Maikap, Abhilasha Singh, Sudeshna Acharyya & Sonali Paul

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Contributions

Susmita Mukherjee: Conceptualization and supervision. Nivedita Chatterjee: Investigation and data analyses. Asmeeta Sircar: Writing original draft. Shimantika Maikap: Resources. Abhilasha Singh: Writing original draft. Sudeshna Acharyya: Writing original draft. Sonali Paul: Supervision and writing—reviewing and editing.

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Correspondence to Sonali Paul.

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Mukherjee, S., Chatterjee, N., Sircar, A. et al. A Comparative Analysis of Heavy Metal Effects on Medicinal Plants. Appl Biochem Biotechnol 195, 2483–2518 (2023). https://doi.org/10.1007/s12010-022-03938-0

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