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Efficacy of oral methotrexate pulsed therapy in eales disease

  • Original Article
  • Published:
Annals of Ophthalmology

Abstract

A prospective study was undertaken to evaluate oral methotrexate pulsed therapy in 6 cases of Eales disease presenting with perivasculitis. Methotrexate was administered (7.5 mg weekly) for 3 months. The therapy was tolerated well, and retinal perivasculitis subsided in all cases. Five patients achieved excellent visual acuity—6/6 (20/20) or better. Elevated titers of C-reactive protein returned to normal after therapy. Six-month follow-up revealed no recurrence of the disease.

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Authors and Affiliations

  1. Retina Service Department of Ophthalmology, King George's Medical College, University of Lucknow, G-19 River Bank Colony, 226018, Lucknow, Uttar Pradesh, India

    Sandeep Saxena MS & Dipak Kumar MS

  2. Department of Microbiology, King George's Medical College, University of Lucknow, Lucknow, India

    Sangeeta Kapoor MBBS

Authors
  1. Sandeep Saxena MS
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  2. Dipak Kumar MS
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  3. Sangeeta Kapoor MBBS
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Saxena, S., Kumar, D. & Kapoor, S. Efficacy of oral methotrexate pulsed therapy in eales disease. Ann Ophthalmol 32, 60–62 (2000). https://doi.org/10.1007/s12009-000-0014-5

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  • DOI: https://doi.org/10.1007/s12009-000-0014-5

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