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Management of Aortic Dissection: Medical Therapy and Intervention. Is There a Growing Role for Endovascular Techniques?

  • Vascular Disease (I Weinberg, Section Editor)
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Opinion statement

Historically, type B aortic dissection was managed as a medical condition with limited surgical intervention unless aortic rupture occurred. Today, however, evidence is building that highlights the importance of strict medical management, timely surveillance, and windows of opportunity for surgical intervention to address both early and late aortic-based morbidities.

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  1. Clouse WD, Hallett Jr JW, Schaff HV, Spittell PC, Rowland CM, Ilstrup DM, et al. Acute aortic dissection: population-based incidence compared with degenerative aortic aneurysm rupture. Mayo Clin Proc. 2004;79(2):176–80.

    Article  PubMed  Google Scholar 

  2. Landenhed M, Engstrom G, Gottsater A, Caulfield MP, Hedblad B, Newton-Cheh C, et al. Risk profiles for aortic dissection and ruptured or surgically treated aneurysms: a prospective cohort study. J Am Heart Assoc. 2015;21:4(1).

    Google Scholar 

  3. Hirst Jr AE, Johns Jr VJ, Kime Jr SW. Dissecting aneurysm of the aorta: a review of 505 cases. Medicine. 1958;37:217–79.

    Article  PubMed  Google Scholar 

  4. Tolenaar JL, Froehlich W, Jonker FH, Upchurch Jr GR, Rampoli V, Tsai TT, et al. Predicting in-hospital mortality in acute type B aortic dissection: evidence from International Registry of Acute Aortic Dissection. Circulation. 2014;120(11 Suppl 1):S45–50.

    Article  Google Scholar 

  5. Crawford ES. The diagnosis and management of aortic dissection. JAMA. 1990;264(19):2537–41.

    Article  CAS  PubMed  Google Scholar 

  6. Hagan PG, Nienaber CA, Isselbacher EM, Bruckman D, Karavite DJ, Russman PL, et al. The International Registry of Acute Aortic Dissection (IRAD): new insights into an old disease. JAMA. 2000;283(7):897–903. IRAD is a consortium comprised of 11 countries and 30 large referral centers participating in a registry to assess multiple factors and outcomes of acute aortic dissection. This is the first publication of many; this evaluates risk factors and short term outcomes.

    Article  CAS  PubMed  Google Scholar 

  7. Williams DM, LePage MA, Lee DY. The dissected aorta: part I. Early anatomic changes in an in vitro model. Radiology. 1997;203:23–31.

    Article  CAS  PubMed  Google Scholar 

  8. Oderich GS, Panneton JM, Bower TC, Ricotta 2nd JJ, Sundt 3rd TM, Cha S, et al. Aortic dissection with aortic side branch compromise: impact of malperfusion on patient outcome. Perspect Vasc Surg Endovasc Ther. 2008;20(2):190–200.

    Article  PubMed  Google Scholar 

  9. Williams DM, Lee DY, Hamilton BH, Marx MV, Narasimham DL, Kazamjian SN, et al. The dissected aorta: part III. Anatomy and radiologic diagnosis of branch-vessel compromise. Radiology. 1997;203(1):37–44.

    Article  CAS  PubMed  Google Scholar 

  10. Tsai TT, Trimarchi S, Nienaber CA. Acute aortic dissection: perspectives from the International Registry of Acute Aortic Dissection (IRAD). Eur J Vasc Endovasc Surg. 2009;37(2):149–59.

    Article  CAS  PubMed  Google Scholar 

  11. Hsue PY, Salinas CL, Bolger AF, Benowitz NL, Waters DD. Acute aortic dissection related to crack cocaine. Circulation. 2002;105(1):1592–5.

    Article  PubMed  Google Scholar 

  12. Kolodgie FD, Virmani R, Cornhil JF, Herderick EE, Smialek J. Increase in atherosclerosis and adventitial mast cells in cocaine abusers: an alternative mechanism of cocaine-associated coronary vasospasm and thrombosis. J Am Coll Cardiol. 1991;17(7):1553–60.

    Article  CAS  PubMed  Google Scholar 

  13. Williams GM, Gott VL, Brawley RK, Schauble JF, Labs JD. Aortic disease associated with pregnancy. J Vasc Surg. 1988;8(4):470–5.

    Article  CAS  PubMed  Google Scholar 

  14. Isselbacher EM. Diseases of the aorta. Braunwald E heart disease. Philadelphia: WB Saunders; 2002. p. 1422–55.

    Google Scholar 

  15. Mackenzie KS, LeGuillan MP, Steinmetz OK, Montreuil B. Management trends and early mortality rates for acute type B aortic dissection: a 10-year single-institution experience. Ann Vasc Surg. 2004;18:158–66.

    Article  PubMed  Google Scholar 

  16. Hiratzka LF, Bakris GL, Beckman JA, Bersin RM, Carr VF, Casey Jr DE, et al. American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines; American Association for Thoracic Surgery; American College of Radiology; American Stroke Association; Society of Cardiovascular Anesthesiologists; Society for Cardiovascular Angiography and Interventions; Society of Interventional Radiology; Society of Thoracic Surgeons; Society for Vascular Medicine. 2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM guidelines for the diagnosis and management of patients with Thoracic Aortic Disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, American Association for Thoracic Surgery, American College of Radiology, American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of Thoracic Surgeons, and Society for Vascular Medicine. Circulation. 2010;121:e266–369.

    Article  PubMed  Google Scholar 

  17. Suzuki T, Mehta RH, Ince H, Nagai R, Sakomura Y, Weber F, et al. IRAD. Clinical profiles and outcomes of acute type B aortic dissection in the current era: lessons from the International Registry of Aortic Dissection (IRAD). Circulation. 2003;108 Suppl 1:II312–7.

    PubMed  Google Scholar 

  18. Estrera AL, Miller CC, Goodrick J, Porat EE, Achouh PE, Dhareshwar J, et al. Update on outcomes of acute type B aortic dissection. Ann Thorac Surg. 2007;83:S842–5.

    Article  PubMed  Google Scholar 

  19. Trimarchi S, Eagle KA, Nienaber CA, Pyeritz RE, Jonker FH, Suzuki T, et al. IRAD. Importance of refractory pain and hypertension in acute type B aortic dissection: insights from the International Registry of Acute Aortic Dissection (IRAD). Circulation. 2010;122:1283–9.

    Article  PubMed  Google Scholar 

  20. Trimarchi S, Tolenaar JL, Tsai TT, Froehlich J, Pegorer M, Upchurch GR, et al. Influence of clinical presentation on the outcome of acute B aortic dissection: evidences from IRAD. J Cardiovasc Surg (Torino). 2012;53:161–8.

    CAS  Google Scholar 

  21. Suzuki T, Isselbacher EM, Nienaber CA, Pyeritz RE, Eagle KA, Tsai TT, et al. IRAD. Type-selective benefits of medications in treatment of acute aortic dissection (from the International Registry of Acute Aortic Dissection [IRAD]). Am J Cardiol. 2012;109:122–7.

    Article  CAS  PubMed  Google Scholar 

  22. Mochizuki S, Dahlof B, Shimizu M, Ikewaki K, Yoshikawa M, Taniguchi I, et al. Valsartan in a Japanese population with hypertension and other cardiovascular disease (Jikei Heart Study): a randomised, open-label, blinded endpoint morbidity-mortality study. Lancet. 2007;369:1431–9.

    Article  CAS  PubMed  Google Scholar 

  23. Neal B, MacMahon S, Chapman N. Effects of ACE inhibitors, calcium antagonists, and other blood-pressure-lowering drugs: results of prospectively designed overviews of randomised trials. Blood Pressure Lowering Treatment Trialists' Collaboration. Lancet. 2000;356:1955–64.

    Article  CAS  PubMed  Google Scholar 

  24. Chiu HH, Wu MH, Wang JK, Lu CW, Chiu SN, Chen CA, et al. Losartan added to beta-blockade therapy for aortic root dilation in Marfan syndrome: a randomized, open-label pilot study. Mayo Clin Proc. 2013;88(3):271–6.

    Article  CAS  PubMed  Google Scholar 

  25. Pees C, Laccone F, Hagl M, Debrauwer V, Moser E, Michel-Behnke I. Usefulness of losartan on the size of the ascending aorta in an unselected cohort of children, adolescents, and young adults with Marfan syndrome. Am J Cardiol. 2013;112(9):1477–83.

    Article  CAS  PubMed  Google Scholar 

  26. Groenink M, den Hartog AW, Franken R, Radonic T, de Waard V, Timmermans J, et al. Losartan reduces aortic dilatation rate in adults with Marfan syndrome: a randomized controlled trial. Eur Heart J. 2013;34(45):3491–500.

    Article  CAS  PubMed  Google Scholar 

  27. Coselli JS. Thoracoabdominal aortic aneurysms: experience with 372 patients. J Card Surg. 1994;9(6):638–47.

    Article  CAS  PubMed  Google Scholar 

  28. Svensson LG, Crawford ES, Hess KR, Coselli JS, Safi HJ. Dissection of the aorta and dissecting aortic aneurysms. Improving early and long-term surgical results. Circulation. 1990;82(5 Suppl):IV24–38.

    CAS  PubMed  Google Scholar 

  29. Verdant A, Cossette R, Page A, Baillot R, Dontigny L, Page P. Aneurysms of the descending thoracic aorta: three hundred sixty six consecutive cases resected without paraplegia. J Vasc Surg. 1995;21(3):385–90. discussion 390-1.

    Article  CAS  PubMed  Google Scholar 

  30. Trimarchi S, Nienaber CA, Rampoldi V, Myrmel T, Suzuki T, Bossone E, et al. IRAD. Role and results of surgery in acute type B aortic dissection: insights from the International Registry of Acute Aortic Dissection (IRAD). Circulation. 2006;114(1 Suppl):I357–64.

    PubMed  Google Scholar 

  31. Sasaki S, Yasuda K, Kunihara T, Shiiya N, Murashita T, Matsui Y, et al. Surgical results of Stanford type B aortic dissection. Comparisons between partial and subtotal replacement of the dissected aorta. J Cardiovasc Surg (Torino). 2000;41(2):227–32.

    CAS  Google Scholar 

  32. Lansman SL, Hagl C, Fink D, Galla JD, Spielvogel D, Ergin MA, et al. Acute type B aortic dissection: surgical therapy. Ann Thorac Surg. 2002;74(5):S1833–5. discussion.

    Article  PubMed  Google Scholar 

  33. Nienaber CA, Fattori R, Lund G, Dieckmann C, Wolf W, von Kodolitsch Y, et al. Nonsurgical reconstruction of thoracic aortic dissection by stent-graft placement. N Engl J Med. 1999;340(20):1539–45. One of the two sentinel papers describing stent-graft placement for acute aortic dissection.

    Article  CAS  PubMed  Google Scholar 

  34. Dake MD, Kato N, Mitchell RS, Semba CP, Razavi MK, Shimono T, et al. Endovascular stent-graft placement for the treatment of acute aortic dissection. N Engl J Med. 1999;340(20):1546–52. One of the two sentinel papers describing stent-graft placement for acute aortic dissection.

    Article  CAS  PubMed  Google Scholar 

  35. Neinaber CA, Rousseau H, Eggebrecht H, Kische S, Fattori R, Rehders TC, et al. Randomized comparison of strategies for type B aortic dissection: the Investigation of STEnt Grafts in Aortic Dissection (INSTEAD) trial. Circulation. 2009;120(25):2519–28. First randomized comparison of endovascular repair vs maximal medical therapy.

    Article  Google Scholar 

  36. Nienaber CA, Kische S, Rousseau H, Eggebrecht H, Rehders TC, Kundt G, et al. Endovascular repair of type B aortic dissection: long term results of the randomized investigation of stent grafts in aortic dissection trial (INSTEAD-XL). Circ Cardiovasc Interv. 2013;6:407–16. Two-year follow up of INSTEAD trial showing excellent aortic remodeling in the TEVAR group but no improvement in 2-year survival.

    Article  CAS  PubMed  Google Scholar 

  37. Fattori R, Montgomery D, Lovato L, Kische S, Di Eusanio M, Ince H, et al. Survival after endovascular therapy in patients with type B aortic dissection: a report from the International Registry of Acute Aortic Dissection (IRAD). JACC Cardiovasc Interv. 2013;6(8):876–82.

    Article  PubMed  Google Scholar 

  38. Deeb GM, Patel HJ, Williams DM. Treatment for malperfusion syndrome in acute type A and B aortic dissection: a long-term analysis. J Thorac Cardiovasc Surg. 2010;140(6 Suppl):S98–100. discussion S142-S146.

    Article  PubMed  Google Scholar 

  39. Midulla M, Renaud A, Martinelli T, Koussa M, Mounier-Vehier C, Prat A, et al. Endovascular fenestration in aortic dissection with acute malperfusion syndrome: immediate and late follow-up. J Thorac Cardiovasc Surg. 2011;142(1):66–72.

    Article  PubMed  Google Scholar 

  40. Clair DG. Aortic dissection with branch vessel occlusion: percutaneous treatment with fenestration and stenting. Semin Vasc Surg. 2002;15(2):116–21.

    Article  PubMed  Google Scholar 

  41. Beregi JP, Prat A, Gaxotte V, Delomez M, McFadden EP. Endovascular treatment for dissection of the descending aorta. Lancet. 2000;356(9228):482–3.

    Article  CAS  PubMed  Google Scholar 

  42. Slonim SM, Miller DC, Mitchell RS, Semba CP, Razavi MK, Dake MD. Percutaneous balloon fenestration and stenting for life-threatening ischemic complications in patients with acute aortic dissection. J Thorac Cardiovasc Surg. 1999;117(6):1118–26.

    Article  CAS  PubMed  Google Scholar 

  43. Heijmen R, Fattori R, Thompson M, Eggebrecht H, Degriecke I, Nienaber C, et al. Virtue Registry Investigators. The VIRTUE Registry of type B thoracic dissections—study design and early results. Eur J Vasc Endovasc Surg. 2011;41:159–66.

    Article  Google Scholar 

  44. Eggebrecht H, Nienaber CA, Neuhauser M, Baumgart D, Kische S, Schmermund A, et al. Endovascular stent-graft placement in aortic dissection: a meta-analysis. Eur Heart J. 2006;27:489–98.

    Article  PubMed  Google Scholar 

  45. Parker JD, Golledge J. Outcome of endovascular treatment of acute type B aortic dissection. Ann Thorac Surg. 2008;86:1707–12.

    Article  PubMed  Google Scholar 

  46. Xiong J, Jiang B, Guo W, Wang SM, Tong XY. Endovascular stent graft placement in patients with type B aortic dissection: a meta-analysis in China. J Thorac Cardiovasc Surg. 2009;138:865–72.

    Article  PubMed  Google Scholar 

  47. Lombardi JV, Cambria RP, Nienaber CA, Chiesa R, Teebken O, Lee A, et al. STABLE. Prospective multicenter clinical trial (STABLE) on the endovascular treatment of complicated type B aortic dissection using a composite device design. J Vasc Surg. 2012;55:629–40.

    Article  PubMed  Google Scholar 

  48. Tsai TT, Fattori R, Trimarchi S, Isselbacher E, Myrmel T, Evangelista A, et al. Long-term survival in patients presenting with type B acute aortic dissection: insights from the International Registry of Acute Aortic Dissection. Circulation. 2006;114:2226–31.

    Article  PubMed  Google Scholar 

  49. Cambria RP, Crawford RS, Cho JS, Bavaria J, Farber M, Lee WA, et al. A multicenter clinical trial of endovascular stent graft repair of acute catastrophes of the descending thoracic aorta. J Vasc Surg. 2009;50:1255–64.

    Article  PubMed  Google Scholar 

  50. Zeeshan A, Woo EY, Bavaria JE, Fairman RM, Desai ND, Pochettino A, et al. Thoracic endovascular aortic repair for acute complicated type B aortic dissection: superiority relative to conventional open surgical and medical therapy. J Thorac Cardiovasc Surg. 2010;140(Suppl):S109–15.

    Article  PubMed  Google Scholar 

  51. Svensson LG, Kouchoukos NT, Miller DC, Bavaria JE, Coselli JS, Curi MA, et al. Expert consensus document on the treatment of descending thoracic aortic disease using endovascular stent-grafts. Ann Thorac Surg. 2008;85:S1–41.

    Article  PubMed  Google Scholar 

  52. Verhoye JP, Miller DC, Sze D, Dake MD, Mitchell RS. Complicated acute type B aortic dissection: midterm results of emergency endovascular stentgrafting. J Thorac Cardiovasc Surg. 2008;136:424–30.

    Article  PubMed  Google Scholar 

  53. Steuer J, Eriksson MO, Nyman R, Bjorck M, Wanhainen A. Early and long term outcome after thoracic endovascular aortic repair (TEVAR) for acute complicated type B aortic dissection. Eur J Vasc Endovasc Surg. 2011;41:318–23.

    Article  CAS  PubMed  Google Scholar 

  54. Fattori R, Tsai TT, Myrmel T, Evangelista A, Cooper JV, Trimarchi S, et al. Complicated acute type B dissection: is surgery still the best option? A report from the International Registry of Acute Aortic Dissection. JACC Cardiovasc Interv. 2008;1:395–402.

    Article  PubMed  Google Scholar 

  55. Khoynezhad A, Donayre CE, Omari BO, Kopchok GE, Walot I, White RA. Midterm results of endovascular treatment of complicated acute type B aortic dissection. J Thorac Cardiovasc Surg. 2009;138:625–31.

    Article  PubMed  Google Scholar 

  56. Kasirajan K, Dake MD, Lumsden A, Bavaria J, Makaroun MS. Incidence and outcomes after infolding or collapse of thoracic stent grafts. J Vasc Surg. 2012;55:652–8.

    Article  PubMed  Google Scholar 

  57. Eggebrecht H, Thompson M, Rousseau H, Czerny M, Lonn L, Mehta RH, et al. Retrograde ascending aortic dissection during or after thoracic aortic stent graft placement: insight from the European registry on endovascular aortic repair complications. Circulation. 2009;120(Suppl):S276–81.

    Article  PubMed  Google Scholar 

  58. Buth J, Harris PL, Hobo R, van Eps R, Cuypers P, Duijm L, et al. Neurologic complications associated with endovascular repair of thoracic aortic pathology: incidence and risk factors. A study from the European Collaborators on Stent/Graft Techniques for Aortic Aneurysm Repair (EUROSTAR) registry. J Vasc Surg. 2007;46:1103–10.

    Article  PubMed  Google Scholar 

  59. Coselli JS, LeMaire SA, Koksoy C, Schmittling ZC, Curling PE. Cerebrospinal fluid drainage reduces paraplegia after thoracoabdominal aortic aneurysm repair: results of a randomized clinical trial. J Vasc Surg. 2002;35:631–9.

    Article  PubMed  Google Scholar 

  60. Svensson LG, Crawford ES, Hess KR, Coselli JS, Safi HJ. Experience with 1509 patients undergoing thoracoabdominal aortic operations. J Vasc Surg. 1993;17:357–68.

    Article  CAS  PubMed  Google Scholar 

  61. Jacobs MJ, Mess W, Mochtar B, Nijenhuis RJ, Statius van Eps RG, Schurink GW. The value of motor evoked potentials in reducing paraplegia during thoracoabdominal aneurysm repair. J Vasc Surg. 2006;43:239–46.

    Article  PubMed  Google Scholar 

  62. Nijenhuis RJ, Jacobs MJ, Schurink GW, Kessels AGH, Van Engelshoven JMA, Backes WH. Comparison of magnetic resonance with computed tomography angiography for preoperative localization of the Adamkiewicz artery in thoracoabdominal aortic aneurysm patients. J Vasc Surg. 2007;45:677–85.

    Article  PubMed  Google Scholar 

  63. Coselli JS. The use of left heart bypass in the repair of thoracoabdominal aortic aneurysms: current techniques and results. Semin Thorac Cardiovasc Surg. 2003;15:326–32.

    Article  PubMed  Google Scholar 

  64. Kulik A, Castner CF, Kouchoukos NT. Outcomes after thoracoabdominal aortic aneurysm repair with hypothermic circulatory arrest. J Thorac Cardiovasc Surg. 2011;141:953–60.

    Article  PubMed  Google Scholar 

  65. Svensson LG, Khitin L, Nadolny EM, Kimmel WA. Systemic temperature and paralysis after thoracoabdominal and descending aortic operations. Arch Surg. 2003;138:175–9.

    Article  PubMed  Google Scholar 

  66. Schlösser FJ, Verhagen HJ, Lin PH, Verhoeven EL, van Herwaarden JA, Moll FL, et al. TEVAR following prior abdominal aortic aneurysm surgery: increased risk of neurological deficit. J Vasc Surg. 2009;49:308–14.

    Article  PubMed  Google Scholar 

  67. Khoynezhad A, Donayre CE, Bui H, Kopchok GE, Walot I, White RA. Risk factors of neurologic deficit after thoracic aortic endografting. Ann Thorac Surg. 2007;83:S882–9.

    Article  PubMed  Google Scholar 

  68. Amabile P, Grisoli D, Giorgi R, Bartoli JM, Piquet P. Incidence and determinants of spinal cord ischemia in stent-graft repair of the thoracic aorta. Eur J Vasc Endovasc Surg. 2008;35:455–61.

    Article  CAS  PubMed  Google Scholar 

  69. Khan SN, Stansby GP. Cerebrospinal fluid drainage for thoracic and thoracoabdominal aortic aneurysm surgery. Cochrane Database Syst Rev. 2012. doi:10.1002/14651858.CD003635.pub3.

    Google Scholar 

  70. Lima B, Nowicki ER, Blackstone EH, Williams SJ, Roselli EE, Sabik 3rd JF, et al. Spinal cord protective strategies during descending and thoracoabdominal aortic aneurysm repair in the modern era: the role of intrathecal papaverine. J Thorac Cardiovasc Surg. 2012;143:945–52.

    Article  CAS  PubMed  Google Scholar 

  71. Wynn MM, Mell MW, Tefera G, Hoch JR, Acher CW. Complications of spinal fluid drainage in thoracoabdominal aortic aneurysm repair: a report of 486 patients treated from 1987 to 2008. J Vasc Surg. 2009;49:29–34.

    Article  PubMed  Google Scholar 

  72. Jonker FH, Trimarchi S, Muhs BE, Rampoldi V, Montgomery DG, Froehlich JB, et al. The role of age in complicated acute type B aortic dissection. Ann Thorac Surg. 2013;96(6):2129–34.

    Article  PubMed  Google Scholar 

  73. Elkayam U, Ostrzega E, Shotan A, Mehra A. Cardiovascular problems in pregnant women with the Marfan syndrome. Ann Intern Med. 1995;123(2):117–22.

    Article  CAS  PubMed  Google Scholar 

  74. Zeebregts CJ, Schepens MA, Hameeteman TM, Morshuis WJ, de la Riviere AB. Acute aortic dissection complicating pregnancy. Ann Thorac Surg. 1997;64(5):1345–8.

    Article  CAS  PubMed  Google Scholar 

  75. Task Force on the Management of Cardiovascular Diseases During Pregnancy of the European Society of Cardiology. Expert consensus document on management of cardiovascular diseases during pregnancy. Eur Heart J. 2003;24(8):761–81.

    Article  Google Scholar 

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Kristine C. Orion and James H. Black III each declare no potential conflicts of interest.

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  1. Department of Surgery, The Johns Hopkins Hospital, 600 N. Wolfe Street, Halsted 668, Baltimore, MD, 21287, USA

    Kristine C. Orion MD & James H. Black III MD

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Orion, K.C., Black, J.H. Management of Aortic Dissection: Medical Therapy and Intervention. Is There a Growing Role for Endovascular Techniques?. Curr Treat Options Cardio Med 17, 24 (2015). https://doi.org/10.1007/s11936-015-0386-x

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