Skip to main content

Advertisement

Log in

Retropubic Versus Transobturator Slings—Are the Outcomes Changing with Time?

  • Lower Urinary Tract Symptoms and Voiding Dysfunction (G Badlani and H Goldman, Section Editors)
  • Published:
Current Urology Reports Aims and scope Submit manuscript

Abstract

The purpose of this review is to review the most current patient reported (subjective) and physician reported (objective) outcomes and adverse events associated with retropubic (RMUS) and transobturator (TMUS) mid-urethral slings. Since the two landmark meta-analyses published in 2010, four new RCT have been published and five have reported long-term outcomes comparing RMUS versus TMUS. Both RMUS and TMUS are safe and have efficacious longer-term outcomes. There is no difference between these slings’ subjective outcomes. There is still debate regarding whether RMUS is slightly superior when assessing objective outcomes. Although three trials showed no difference in objective outcomes, results from the largest trial show that RMUS is superior. Further analysis suggests that women with poor urethral function have less favorable outcomes with TMUS and may do better with RMUS. Adverse events are common, and they differ depending on the surgical approach. These new trials confirm previous reported adverse events.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. Ulmsten U, Petros P. Intravaginal slingplasty (IVS): an ambulatory surgical procedure for treatment of female urinary incontinence. Scand J Urol Nephrol. 1995;29:75–82.

    Article  PubMed  CAS  Google Scholar 

  2. Petros PE, Ulmsten UI. An integral theory of female urinary incontinence. Experimental and clinical considerations. Acta Obstet Gynecol Scand Suppl. 1990;153:7–31.

    Article  PubMed  CAS  Google Scholar 

  3. •• Ogah J, Cody JD, Rogerson L. Minimally invasive synthetic suburethral sling operations for stress urinary incontinence in women. Cochrane Database Syst Rev. 2009;4, CD006375. Cochrane review (meta-analysis) comparing colposuspension, pubovaginal sling and mid-urethral slings subjective and objective outcomes at one year, as well as adverse events in the treatment of stress urinary incontinence. The authors found no difference in patientsreported symptoms when comparing retropubic versus transobturator slings.

    PubMed  Google Scholar 

  4. Delorme E. Transobturator urethral suspension: mini-invasive procedure in the treatment of stress urinary incontinence in women. Prog Urol. 2001;11:1306–13.

    PubMed  CAS  Google Scholar 

  5. de Leval J. Novel surgical technique for the treatment of female stress urinary incontinence: transobturator vaginal tape inside-out. Eur Urol. 2003;44:724–30.

    Article  PubMed  Google Scholar 

  6. Latthe PM, Foon R, Toozs-Hobson P. Transobturator and retropubic tape procedures in stress urinary incontinence: a systematic review and meta-analysis of effectiveness and complications. BJOG. 2007;114:522–31.

    Article  PubMed  CAS  Google Scholar 

  7. •• Novara G, Artibani W, Barber MD, et al. Updated systematic review and meta-analysis of the comparative data on colposuspensions, pubovaginal slings, and midurethral tapes in the surgical treatment of female stress urinary incontinence. Eur Urol. 2010;58:218–38. Comprehensive meta-analysis comparing colposuspension, pubovaginal sling and mid-urethral slings subjective and objective outcomes at one year, as well as adverse events in the treatment of stress urinary incontinence. The authors found no difference in patientsreported symptoms when comparing retropubic versus transobturator slings.

    Article  PubMed  Google Scholar 

  8. Dmochowski RR, Blaivas JM, Gormley EA, et al. Update of AUA guideline on the surgical management of female stress urinary incontinence. J Urol. 2010;183:1906–14.

    Article  PubMed  Google Scholar 

  9. Abdel-Fattah M, Ford JA, Lim CP, et al. Single-incision mini-slings versus standard midurethral slings in surgical management of female stress urinary incontinence: a meta-analysis of effectiveness and complications. Eur Urol. 2011;60:468–80.

    Article  PubMed  Google Scholar 

  10. Appell RA, Dmochowski R, Blaivas J, et al. Guideline for the surgical management of female stress urinary incontinence: Update (2009); 2012.

  11. Lucas M, Bedretdinova D, Bosch J, et al. Guidelines on urinary incontinence; 2012.

  12. • Schierlitz L, Dwyer PL, Rosamilia A, et al. Three-year follow-up of tension-free vaginal tape compared with transobturator tape in women with stress urinary incontinence and intrinsic sphincter deficiency. Obstet Gynecol. 2012;119:321–7. RCT comparing retropubic versus transobturator mid-urethral slings for the treatment of female incontinence with 3-year subjective and objective outcomes. These women had intrinsic sphinteric deficiency. Despite no difference in subjective outcomes, there was a significant difference on objective outcomes favoring the retropubic approach.

    Article  PubMed  Google Scholar 

  13. • Albo ME, Litman HJ, Richter HE, et al. Treatment success of retropubic and transobturator mid urethral slings at 24 months. J Urol. 2012;188:2281–7. Largest multi-institutional RCT comparing retropubic versus transobturator mid-urethral slings for the treatment of female incontinence with 2-year subjective and objective outcomes. Predetermined confidence interval equivalence was not met between the sling groups, favoring the retropubic approach when evaluating both subjective and objective outcomes at 2 years.

    Article  PubMed  Google Scholar 

  14. Cerruto MA, Artibani W. Transobturator versus retropubic synthetic slings: comparative efficacy and safety. Curr Opin Urol. 2011;21:275–80.

    Article  PubMed  Google Scholar 

  15. Jain P, Jirschele K, Botros SM, et al. Effectiveness of midurethral slings in mixed urinary incontinence: a systematic review and meta-analysis. Int Urogynecol J. 2011;22:923–32.

    Article  PubMed  Google Scholar 

  16. Pradhan A, Jain P, Latthe PM. Effectiveness of midurethral slings in recurrent stress urinary incontinence: a systematic review and meta-analysis. Int Urogynecol J. 2012;23:831–41.

    Article  PubMed  Google Scholar 

  17. Bakali E, Buckley BS, Hilton P, et al. Treatment of recurrent stress urinary incontinence after failed minimally invasive synthetic suburethral tape surgery in women. Cochrane Database Syst Rev. 2013;2, CD009407.

    PubMed  Google Scholar 

  18. Madhuvrata P, Riad M, Ammembal MK, et al. Systematic review and meta-analysis of “inside-out” versus “outside-in” transobturator tapes in management of stress urinary incontinence in women. Eur J Obstet Gynecol Reprod Biol. 2012;162:1–10.

    Article  PubMed  Google Scholar 

  19. Zhu YF, Gao GL, He LS, et al. Inside out transobturator vaginal tape versus tention-free vaginal tape for primary female stress urinary incontinence: meta-analysis of randomized controlled trials. Chin Med J (Engl). 2012;125:1316–21.

    PubMed  Google Scholar 

  20. Jha S, Ammenbal M, Metwally M. Impact of incontinence surgery on sexual function: a systematic review and meta-analysis. J Sex Med. 2012;9:34–43.

    Article  PubMed  Google Scholar 

  21. Tanuri AL, Feldner Jr PC, Bella ZI, et al. Retropubic and transobturator sling in treatment of stress urinary incontinence. Rev Assoc Med Bras. 2010;56:348–54.

    Article  PubMed  Google Scholar 

  22. Chen Z, Chen Y, Du GH, et al. Comparison of three kinds of mid-urethral slings for surgical treatment of female stress urinary incontinence. Urologia. 2010;77:37–41. discussion 42.

    PubMed  Google Scholar 

  23. Teo R, Moran P, Mayne C, et al. Randomized trial of tension-free vaginal tape and tension-free vaginal tape-obturator for urodynamic stress incontinence in women. J Urol. 2011;185:1350–5.

    Article  PubMed  Google Scholar 

  24. Deffieux X, Daher N, Mansoor A, et al. Tension-free vaginal tape(TVT) and trans-obturator suburethral tape from inside to outside (TVT-O) for surgical treatment of female stress urinary incontinence: a multicenter randomized controlld trial [abstract]. Int Urogynecol J. 2007;18:S19.

    Article  Google Scholar 

  25. Rinne K, Laurikainen E, Kivela A, et al. A randomized trial comparing TVT with TVT-O: 12-month results. Int Urogynecol J Pelvic Floor Dysfunct. 2008;19:1049–54.

    Article  PubMed  Google Scholar 

  26. Zullo MA, Plotti F, Calcagno M, et al. One-year follow-up of tension-free vaginal tape (TVT) and trans-obturator suburethral tape from inside to outside (TVT-O) for surgical treatment of female stress urinary incontinence: a prospective randomised trial. Eur Urol. 2007;51:1376–82. discussion 1383-4.

    Article  PubMed  Google Scholar 

  27. • Deffieux X, Daher N, Mansoor A, et al. Transobturator TVT-O versus retropubic TVT: results of a multicenter randomized controlled trial at 24 months follow-up. Int Urogynecol J. 2010;21:1337–45. Multi-institutional RCT comparing retropubic versus transobturator mid-urethral slings for the treatment of female incontinence with 2-year subjective and objective outcomes. Authors found no difference in objective and subjective outcomes.

    Article  PubMed  Google Scholar 

  28. • Angioli R, Plotti F, Muzii L, et al. Tension-free vaginal tape versus transobturator suburethral tape: five-year follow-up results of a prospective, randomised trial. Eur Urol. 2010;58:671–7. Small sample RCT comparing retropubic versus transobturator mid-urethral slings for the treatment of female incontinence with 5-year subjective and objective outcomes. Authors found no difference in objective and subjective outcomes.

    Article  PubMed  Google Scholar 

  29. Palva K, Rinne K, Aukee P, et al. A randomized trial comparing tension-free vaginal tape with tension-free vaginal tape-obturator: 36-month results. Int Urogynecol J. 2010;21:1049–55.

    Article  PubMed  Google Scholar 

  30. Richter HE, Albo ME, Zyczynski HM, et al. Retropubic versus transobturator midurethral slings for stress incontinence. N Engl J Med. 2010;362:2066–76.

    Article  PubMed  CAS  Google Scholar 

  31. Nager CW, Sirls L, Litman HJ, et al. Baseline urodynamic predictors of treatment failure 1 year after mid urethral sling surgery. J Urol. 2011;186:597–603.

    Article  PubMed  Google Scholar 

  32. • Brubaker L, Norton PA, Albo ME, et al. Adverse events over two years after retropubic or transobturator midurethral sling surgery: findings from the Trial of Midurethral Slings (TOMUS) study. Am J Obstet Gynecol. 2011;205:498.e1–6. This is comprehensive adverse events data after a 2-year follow-up of the same patients in Albos paper, reference 13. The authors reported that adverse events are common and they differ depending on the surgical approach.

    Article  Google Scholar 

  33. Haliloglu B, Karateke A, Coksuer H, et al. The role of urethral hypermobility and intrinsic sphincteric deficiency on the outcome of transobturator tape procedure: a prospective study with 2-year follow-up. Int Urogynecol J. 2010;21:173–8.

    Article  PubMed  Google Scholar 

  34. Rechberger T, Futyma K, Jankiewicz K, et al. The clinical effectiveness of retropubic (IVS-02) and transobturator (IVS-04) midurethral slings: randomized trial. Eur Urol. 2009;56:24–30.

    Article  PubMed  CAS  Google Scholar 

  35. Schierlitz L, Dwyer PL, Rosamilia A, et al. Effectiveness of tension-free vaginal tape compared with transobturator tape in women with stress urinary incontinence and intrinsic sphincter deficiency: a randomized controlled trial. Obstet Gynecol. 2008;112:1253–61.

    Article  PubMed  Google Scholar 

  36. Abdel-Fattah M, Ramsay I, Pringle S, et al. Evaluation of transobturator tension-free vaginal tapes in management of women with recurrent stress urinary incontinence. Urology. 2011;77:1070–5.

    Article  PubMed  Google Scholar 

  37. Stav K, Dwyer PL, Rosamilia A, et al. Repeat synthetic mid urethral sling procedure for women with recurrent stress urinary incontinence. J Urol. 2010;183:241–6.

    Article  PubMed  Google Scholar 

Download references

Compliance with Ethics Guidelines

Conflict of Interest

Dr. Paholo Barboglio Romo reported no potential conflicts of interest relevant to this article.

Dr. Elizabeth Ann Gormley is Chair of the Urinary Incontinence Treatment Network for NIH-NIDDH and reported receiving payment for manuscript preparation from Astellas.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to E. Ann Gormley.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Barboglio, P.G., Gormley, E.A. Retropubic Versus Transobturator Slings—Are the Outcomes Changing with Time?. Curr Urol Rep 14, 386–394 (2013). https://doi.org/10.1007/s11934-013-0337-6

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11934-013-0337-6

Keywords

Navigation