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Emerging role of botulinum toxin in the treatment of neurogenic and non-neurogenic voiding dysfunction

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Abstract

Botulinum toxin (BTX) is the most lethal naturally occurring toxin known to mankind. Why, then, would an urologist want to use this agent to poison the bladder or urethral sphincter? This article reviews the mechanisms underlying the effects of BTX treatment, summarizes the current usage of this agent within the urologic community, and provides perspectives on future targets of this therapy.

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Authors and Affiliations

  1. Department of Urology, Obstetrics, and Gynecology, University of Pittsburgh School of Medicine, 700 LS Kaufmann Building, 3471 Fifth Avenue, 15213, Pittsburgh, PA, USA

    Michael B. Chancellor hMD

Authors
  1. Christopher P. Smith MD
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  2. George T Somogyi MD
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  3. Michael B. Chancellor hMD
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Smith, C.P., Somogyi, G.T. & Chancellor, M.B. Emerging role of botulinum toxin in the treatment of neurogenic and non-neurogenic voiding dysfunction. Curr Urol Rep 3, 382–387 (2002). https://doi.org/10.1007/s11934-002-0081-9

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  • DOI: https://doi.org/10.1007/s11934-002-0081-9

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