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From Fracture Risk Prediction to Evaluating Fracture Patterns: Recent Advances in the Epidemiology of Osteoporosis

  • OSTEOPOROSIS AND METABOLIC BONE DISEASE (KG SAAG, SECTION EDITOR)
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Abstract

Understanding the factors associated with fracture is one of the main research objective of the osteoporosis epidemiology field. Tools such as FRAX have overall improved the ability of clinicians and researchers to identify individuals at high risk of fragility fractures. However, the performance of these tools in specific subpopulations needs further examination. We highlight recent studies that have shown under- or overestimation of fractures using FRAX in subpopulations, as well as recently proposed modifications to this important algorithm. We also discuss recent evaluations of secular trends in fracture incidence.

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Disclosure

Dr. Wright has received grant support from Amgen.

Dr. Saag has served on a board for the National Osteoporosis Foundation; has served as a consultant for, received honoraria from, and had travel/accommodations expenses covered/reimbursed by Amgen, Eli Lilly and Company, Merck & Co., and Novartis; and has received grant support from Amgen, Merck & Co., Novartis, Eli Lilly and Company, AHRQ, NIAMS, the National Institutes of Health, and the American College of Rheumatology.

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  1. Department of Epidemiology, University of Alabama at Birmingham, 1665 University Blvd, RPHB 523C, Birmingham, AL, 35294, USA

    Nicole C. Wright

  2. Division of Rheumatology and Immunology, University of Alabama at Birmingham, 210 20th St. S, FOT 820, Birmingham, AL, 35294, USA

    Kenneth G. Saag

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Correspondence to Nicole C. Wright.

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Wright, N.C., Saag, K.G. From Fracture Risk Prediction to Evaluating Fracture Patterns: Recent Advances in the Epidemiology of Osteoporosis. Curr Rheumatol Rep 14, 205–211 (2012). https://doi.org/10.1007/s11926-012-0251-9

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