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Carbapenem-Resistant Enterobacteriaceae: Laboratory Detection and Infection Control Practices

  • Healthcare Associated Infections (G Bearman and M Stevens, Section Editors)
  • Published:
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Abstract

Over the past decade, carbapenem-resistant Enterobacteriaceae (CRE) have become one of the most challenging problems in infectious diseases. Fast and accurate detection of carbapenem resistance is crucial for guiding the treatment of the individual patient as well as for instituting proper infection control measures to limit the spread of the organism. Currently there are no consensus recommendations for screening, detection and confirmation of CRE either on the clinical or the laboratory side. In infection control, data from controlled intervention studies is largely missing and most recommendations have been deduced from outbreak situations. From the available limited evidence, infection control guidelines have been developed in most countries at national, regional and hospital levels. The aim of this review is to summarize the currently available laboratory methods and infection control options.

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Conflict of Interest

Eva-Brigitta Kruse and Ute Aurbach declare no conflict of interest.

Hilmar Wisplinghoff has received payment for development of educational presentations and travel and accommodation reimbursement from Siemens and Bruker Daltonics.

Human and Animal Rights and Informed Consent

This article does not report any studies with human or animal subjects performed by any of the authors.

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Authors and Affiliations

  1. Laboratoriumsmedizin Köln, Dres. med. Wisplinghoff und Kollegen, Cologne, Germany

    Eva-Brigitta Kruse, Ute Aurbach & Hilmar Wisplinghoff

  2. Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Goldenfels Str. 19-21, 50935, Cologne, Germany

    Hilmar Wisplinghoff

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  1. Eva-Brigitta Kruse
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  2. Ute Aurbach
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  3. Hilmar Wisplinghoff
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Correspondence to Hilmar Wisplinghoff.

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Kruse, EB., Aurbach, U. & Wisplinghoff, H. Carbapenem-Resistant Enterobacteriaceae: Laboratory Detection and Infection Control Practices. Curr Infect Dis Rep 15, 549–558 (2013). https://doi.org/10.1007/s11908-013-0373-x

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